Gene name: UBA4
Reference locus (S288C): YHR111W
Gene biotype: protein_coding
Description: Adenylyltransferase and sulfurtransferase UBA4; E1-like protein that activates Urm1p before urmylation; also acts in thiolation of the wobble base of cytoplasmic tRNAs by adenylating and then thiolating Urm1p; receives sulfur from Tum1p; In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily
Top 10 interactors (score): NFS1 (0.999); URM1 (0.999); NCS2 (0.998); NCS6 (0.997); TUM1 (0.997); IKI3 (0.978); ELP2 (0.97); MCM5 (0.959); ELP3 (0.958); ELP6 (0.948); SMT3 (0.943); TRM9 (0.942); KTI12 (0.933); ELP4 (0.931); AHP1 (0.911); TRM112 (0.898); CWC25 (0.896); KTI11 (0.843); ATS1 (0.838); ATG12 (0.808)
Homologues (species, bitscore): MOCS3 (Homo sapiens, 292.4); Mocs3 (Mus musculus, 297.0); mocs3 (Danio rerio, 290.0); UBA4 (Xenopus tropicalis, 285.4); CG13090 (Drosophila melanogaster, 321.2); moc-3 (Caenorhabditis elegans, 305.4); CNX5 (Arabidopsis thaliana, 298.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:319992-321314:+ | gene-YHR111W_AKU4011 | rna-NM_001179241.1_AKU4011 | cds-NP_011979.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:196595-197917:- | gene-YHR111W_BG1 | rna-NM_001179241.1_BG1 | cds-NP_011979.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:327286-328608:+ | gene-YHR111W_Bruggeman | rna-NM_001179241.1_Bruggeman | cds-NP_011979.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:322427-323749:+ | gene-YHR111W_CAT1 | rna-NM_001179241.1_CAT1 | cds-NP_011979.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:319015-320337:+ | gene-YHR111W_CBS1585 | rna-NM_001179241.1_CBS1585 | cds-NP_011979.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:316370-317692:+ | gene-YHR111W_CBS436 | rna-NM_001179241.1_CBS436 | cds-NP_011979.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:320825-322147:+ | gene-YHR111W_CBS6412 | rna-NM_001179241.1_CBS6412 | cds-NP_011979.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:320043-321365:+ | gene-YHR111W_CBS6413 | rna-NM_001179241.1_CBS6413 | cds-NP_011979.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:326243-327565:+ | gene-YHR111W_CENPK1137D | rna-NM_001179241.1_CENPK1137D | cds-NP_011979.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:378900-380222:+ | gene-YHR111W_EthanolRed | rna-NM_001179241.1_EthanolRed | cds-NP_011979.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:320388-321710:+ | gene-YHR111W_FaliES1 | rna-NM_001179241.1_FaliES1 | cds-NP_011979.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000045.1:40967-42289:+ | gene-YHR111W_JAY291 | rna-NM_001179241.1_JAY291 | cds-NP_011979.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:327010-328332:+ | gene-YHR111W_MUCL30387 | rna-NM_001179241.1_MUCL30387 | cds-NP_011979.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:326664-327986:+ | gene-YHR111W_MUCL30388 | rna-NM_001179241.1_MUCL30388 | cds-NP_011979.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:319356-320678:+ | gene-YHR111W_MUCL39482 | rna-NM_001179241.1_MUCL39482 | cds-NP_011979.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:325602-326924:+ | gene-YHR111W_MUCL42920 | rna-NM_001179241.1_MUCL42920 | cds-NP_011979.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:332954-334276:+ | gene-YHR111W_NCIM3186 | rna-NM_001179241.1_NCIM3186 | cds-NP_011979.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:321565-322887:+ | gene-YHR111W_NCYC1407 | rna-NM_001179241.1_NCYC1407 | cds-NP_011979.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:321003-322325:+ | gene-YHR111W_PE2H3 | rna-NM_001179241.1_PE2H3 | cds-NP_011979.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:328430-329752:+ | gene-YHR111W_PE2H4 | rna-NM_001179241.1_PE2H4 | cds-NP_011979.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:333072-334394:+ | gene-YHR111W_S288C | rna-NM_001179241.1_S288C | cds-NP_011979.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:24582-25904:- | gene-YHR111W_SA1 | rna-NM_001179241.1_SA1 | cds-NP_011979.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:321471-322793:+ | gene-YHR111W_ThermosaccDry | rna-NM_001179241.1_ThermosaccDry | cds-NP_011979.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:329091-330413:+ | gene-YHR111W_VR1 | rna-NM_001179241.1_VR1 | cds-NP_011979.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:312507-313829:+ | gene-YHR111W_ZTW1 | rna-NM_001179241.1_ZTW1 | cds-NP_011979.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:318166-319488:+ | gene-YHR111W_Sparadoxus | rna-NM_001179241.1_Sparadoxus | cds-NP_011979.1_Sparadoxus | 87.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |