Gene name: UBA3
Reference locus (S288C): YPR066W
Gene biotype: protein_coding
Description: NEDD8-activating enzyme E1 catalytic subunit; Protein that activates Rub1p (NEDD8) before neddylation; acts together with Ula1p; may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
Top 10 interactors (score): UBC12 (0.999); ULA1 (0.999); RUB1 (0.992); DCN1 (0.991); HRT1 (0.988); CUL3 (0.987); CDC53 (0.982); RRI1 (0.973); CTF18 (0.961); URM1 (0.922); CDC34 (0.918); SKP1 (0.914); RTT101 (0.907); YUH1 (0.906); SMT3 (0.902); UBC9 (0.896); UFD4 (0.836); ELC1 (0.835); AOS1 (0.831); YOR314W (0.818)
Homologues (species, bitscore): UBA3 (Homo sapiens, 262.7); Uba3 (Mus musculus, 261.9); uba3 (Danio rerio, 256.5); uba3 (Xenopus tropicalis, 256.1); Uba3 (Drosophila melanogaster, 240.7); rfl-1 (Caenorhabditis elegans, 220.3); ECR1 (Arabidopsis thaliana, 221.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:652891-653790:+ | gene-YPR066W_AKU4011 | rna-NM_001184163.1_AKU4011 | cds-NP_015391.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:243901-244800:- | gene-YPR066W_BG1 | rna-NM_001184163.1_BG1 | cds-NP_015391.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:730558-731457:+ | gene-YPR066W_Bruggeman | rna-NM_001184163.1_Bruggeman | cds-NP_015391.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:774002-774901:+ | gene-YPR066W_CAT1 | rna-NM_001184163.1_CAT1 | cds-NP_015391.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:656579-657478:+ | gene-YPR066W_CBS1585 | rna-NM_001184163.1_CBS1585 | cds-NP_015391.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:670944-671843:+ | gene-YPR066W_CBS436 | rna-NM_001184163.1_CBS436 | cds-NP_015391.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:660326-661225:+ | gene-YPR066W_CBS6412 | rna-NM_001184163.1_CBS6412 | cds-NP_015391.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:653525-654424:+ | gene-YPR066W_CBS6413 | rna-NM_001184163.1_CBS6413 | cds-NP_015391.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:681176-682075:+ | gene-YPR066W_CENPK1137D | rna-NM_001184163.1_CENPK1137D | cds-NP_015391.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:980085-980984:+ | gene-YPR066W_EthanolRed | rna-NM_001184163.1_EthanolRed | cds-NP_015391.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:658722-659621:+ | gene-YPR066W_FaliES1 | rna-NM_001184163.1_FaliES1 | cds-NP_015391.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:30664-31563:+ | gene-YPR066W_JAY291 | rna-NM_001184163.1_JAY291 | cds-NP_015391.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:671818-672717:+ | gene-YPR066W_MUCL30387 | rna-NM_001184163.1_MUCL30387 | cds-NP_015391.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:670523-671422:+ | gene-YPR066W_MUCL30388 | rna-NM_001184163.1_MUCL30388 | cds-NP_015391.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:649836-650735:+ | gene-YPR066W_MUCL39482 | rna-NM_001184163.1_MUCL39482 | cds-NP_015391.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:712659-713558:+ | gene-YPR066W_MUCL42920 | rna-NM_001184163.1_MUCL42920 | cds-NP_015391.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:681196-682095:+ | gene-YPR066W_NCIM3186 | rna-NM_001184163.1_NCIM3186 | cds-NP_015391.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:657764-658663:+ | gene-YPR066W_NCYC1407 | rna-NM_001184163.1_NCYC1407 | cds-NP_015391.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:663967-664866:+ | gene-YPR066W_PE2H3 | rna-NM_001184163.1_PE2H3 | cds-NP_015391.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:663615-664514:+ | gene-YPR066W_PE2H4 | rna-NM_001184163.1_PE2H4 | cds-NP_015391.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:681213-682112:+ | gene-YPR066W_S288C | rna-NM_001184163.1_S288C | cds-NP_015391.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:18578-19477:- | gene-YPR066W_SA1 | rna-NM_001184163.1_SA1 | cds-NP_015391.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:658497-659396:+ | gene-YPR066W_ThermosaccDry | rna-NM_001184163.1_ThermosaccDry | cds-NP_015391.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:674641-675540:+ | gene-YPR066W_VR1 | rna-NM_001184163.1_VR1 | cds-NP_015391.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:657720-658619:+ | gene-YPR066W_ZTW1 | rna-NM_001184163.1_ZTW1 | cds-NP_015391.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:658490-659389:+ | gene-YPR066W_Sparadoxus | rna-NM_001184163.1_Sparadoxus | cds-NP_015391.1_Sparadoxus | 87.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |