Gene name: UBA2
Reference locus (S288C): YDR390C
Gene biotype: protein_coding
Description: Ubiquitin-activating enzyme E1-like; Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
Top 10 interactors (score): UBC9 (0.999); AOS1 (0.999); SMT3 (0.999); ULP1 (0.992); MMS21 (0.989); ULP2 (0.981); SIZ1 (0.981); NFI1 (0.98); TOP2 (0.949); UBC12 (0.938); RAD23 (0.938); ULA1 (0.918); CST9 (0.899); DSK2 (0.899); SUB2 (0.898); CSE1 (0.879); YRB1 (0.872); NAN1 (0.868); MOT1 (0.864); URM1 (0.862)
Homologues (species, bitscore): UBA2 (Homo sapiens, 318.9); Uba2 (Mus musculus, 315.8); uba2 (Danio rerio, 311.2); uba2 (Xenopus tropicalis, 265.8); Uba2 (Drosophila melanogaster, 308.9); uba-2 (Caenorhabditis elegans, 307.8); SAE2 (Arabidopsis thaliana, 280.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1195079-1196989:- | gene-YDR390C_AKU4011 | rna-NM_001180698.3_AKU4011 | cds-NP_010678.3_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:73563-75473:- | gene-YDR390C_BG1 | rna-NM_001180698.3_BG1 | cds-NP_010678.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1225963-1227873:- | gene-YDR390C_Bruggeman | rna-NM_001180698.3_Bruggeman | cds-NP_010678.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1204519-1206429:- | gene-YDR390C_CAT1 | rna-NM_001180698.3_CAT1 | cds-NP_010678.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1190000-1191910:- | gene-YDR390C_CBS1585 | rna-NM_001180698.3_CBS1585 | cds-NP_010678.3_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1208866-1210776:- | gene-YDR390C_CBS436 | rna-NM_001180698.3_CBS436 | cds-NP_010678.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1186053-1187963:- | gene-YDR390C_CBS6412 | rna-NM_001180698.3_CBS6412 | cds-NP_010678.3_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1207908-1209818:- | gene-YDR390C_CBS6413 | rna-NM_001180698.3_CBS6413 | cds-NP_010678.3_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1253601-1255511:- | gene-YDR390C_CENPK1137D | rna-NM_001180698.3_CENPK1137D | cds-NP_010678.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1199484-1201394:- | gene-YDR390C_EthanolRed | rna-NM_001180698.3_EthanolRed | cds-NP_010678.3_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1202794-1204704:- | gene-YDR390C_FaliES1 | rna-NM_001180698.3_FaliES1 | cds-NP_010678.3_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000181.1:50833-52743:+ | gene-YDR390C_JAY291 | rna-NM_001180698.3_JAY291 | cds-NP_010678.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1209525-1211435:- | gene-YDR390C_MUCL30387 | rna-NM_001180698.3_MUCL30387 | cds-NP_010678.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1191637-1193547:- | gene-YDR390C_MUCL30388 | rna-NM_001180698.3_MUCL30388 | cds-NP_010678.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1181328-1183238:- | gene-YDR390C_MUCL39482 | rna-NM_001180698.3_MUCL39482 | cds-NP_010678.3_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1123765-1125675:- | gene-YDR390C_MUCL42920 | rna-NM_001180698.3_MUCL42920 | cds-NP_010678.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1254860-1256770:- | gene-YDR390C_NCIM3186 | rna-NM_001180698.3_NCIM3186 | cds-NP_010678.3_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1195299-1197209:- | gene-YDR390C_NCYC1407 | rna-NM_001180698.3_NCYC1407 | cds-NP_010678.3_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1205426-1207336:- | gene-YDR390C_PE2H3 | rna-NM_001180698.3_PE2H3 | cds-NP_010678.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1210999-1212909:- | gene-YDR390C_PE2H4 | rna-NM_001180698.3_PE2H4 | cds-NP_010678.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1254937-1256847:- | gene-YDR390C_S288C | rna-NM_001180698.3_S288C | cds-NP_010678.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000071.1:50945-52855:+ | gene-YDR390C_SA1 | rna-NM_001180698.3_SA1 | cds-NP_010678.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1207056-1208966:- | gene-YDR390C_ThermosaccDry | rna-NM_001180698.3_ThermosaccDry | cds-NP_010678.3_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1222238-1224148:- | gene-YDR390C_VR1 | rna-NM_001180698.3_VR1 | cds-NP_010678.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:249865-251775:- | gene-YDR390C_ZTW1 | rna-NM_001180698.3_ZTW1 | cds-NP_010678.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1201648-1203558:- | gene-YDR390C_Sparadoxus | rna-NM_001180698.3_Sparadoxus | cds-NP_010678.3_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |