UBA1 (YKL210W)


Gene profile

Gene name: UBA1
Reference locus (S288C): YKL210W
Gene biotype: protein_coding

Description: Ubiquitin activating enzyme (E1); involved in ubiquitin-mediated protein degradation and essential for viability; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): UBC1 (0.999); RAD6 (0.999); UBC4 (0.999); CDC34 (0.999); UBI4 (0.999); RPL40B (0.998); RPS31 (0.998); UBC13 (0.998); UBC11 (0.998); UBC5 (0.997); RPL40A (0.996); UBC7 (0.986); UBC12 (0.977); SMT3 (0.975); YUH1 (0.97); URM1 (0.968); CDC48 (0.956); RAD23 (0.948); RUB1 (0.946); UBC9 (0.944)

Homologues (species, bitscore): UBA1 (Homo sapiens, 1094.7); Uba1 (Mus musculus, 1094.0); uba1 (Danio rerio, 1065.8); uba1 (Xenopus tropicalis, 751.1); Uba1 (Drosophila melanogaster, 994.6); uba-1 (Caenorhabditis elegans, 788.5); UBA2 (Arabidopsis thaliana, 879.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:24990-28064:+ gene-YKL210W_AKU4011 rna-NM_001179775.1_AKU4011 cds-NP_012712.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:2573-5647:+ gene-YKL210W_BG1 rna-NM_001179775.1_BG1 cds-NP_012712.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:43149-46223:+ gene-YKL210W_Bruggeman rna-NM_001179775.1_Bruggeman cds-NP_012712.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:37847-40921:+ gene-YKL210W_CAT1 rna-NM_001179775.1_CAT1 cds-NP_012712.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:37000-40074:+ gene-YKL210W_CBS1585 rna-NM_001179775.1_CBS1585 cds-NP_012712.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:36688-39762:+ gene-YKL210W_CBS436 rna-NM_001179775.1_CBS436 cds-NP_012712.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:22788-25862:+ gene-YKL210W_CBS6412 rna-NM_001179775.1_CBS6412 cds-NP_012712.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:37637-40711:+ gene-YKL210W_CBS6413 rna-NM_001179775.1_CBS6413 cds-NP_012712.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:38941-42015:+ gene-YKL210W_CENPK1137D rna-NM_001179775.1_CENPK1137D cds-NP_012712.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:36958-40032:+ gene-YKL210W_EthanolRed rna-NM_001179775.1_EthanolRed cds-NP_012712.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:37017-40091:+ gene-YKL210W_FaliES1 rna-NM_001179775.1_FaliES1 cds-NP_012712.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:36632-39706:+ gene-YKL210W_JAY291 rna-NM_001179775.1_JAY291 cds-NP_012712.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:45193-48267:+ gene-YKL210W_MUCL30387 rna-NM_001179775.1_MUCL30387 cds-NP_012712.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:39522-42596:+ gene-YKL210W_MUCL30388 rna-NM_001179775.1_MUCL30388 cds-NP_012712.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:37059-40133:+ gene-YKL210W_MUCL39482 rna-NM_001179775.1_MUCL39482 cds-NP_012712.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:40837-43911:+ gene-YKL210W_MUCL42920 rna-NM_001179775.1_MUCL42920 cds-NP_012712.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:39152-42226:+ gene-YKL210W_NCIM3186 rna-NM_001179775.1_NCIM3186 cds-NP_012712.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:37081-40155:+ gene-YKL210W_NCYC1407 rna-NM_001179775.1_NCYC1407 cds-NP_012712.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:45267-48341:+ gene-YKL210W_PE2H3 rna-NM_001179775.1_PE2H3 cds-NP_012712.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:41465-44539:+ gene-YKL210W_PE2H4 rna-NM_001179775.1_PE2H4 cds-NP_012712.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:39163-42237:+ gene-YKL210W_S288C rna-NM_001179775.1_S288C cds-NP_012712.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000092.1:25638-28712:- gene-YKL210W_SA1 rna-NM_001179775.1_SA1 cds-NP_012712.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:37765-40839:+ gene-YKL210W_ThermosaccDry rna-NM_001179775.1_ThermosaccDry cds-NP_012712.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:36873-39947:+ gene-YKL210W_VR1 rna-NM_001179775.1_VR1 cds-NP_012712.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:36682-39756:+ gene-YKL210W_ZTW1 rna-NM_001179775.1_ZTW1 cds-NP_012712.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:45394-48471:+ gene-YKL210W_Sparadoxus rna-NM_001179775.1_Sparadoxus cds-NP_012712.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files