Gene name: TYW3
Reference locus (S288C): YGL050W
Gene biotype: protein_coding
Description: tRNA wybutosine-synthesizing protein 3; tRNA methyltransferase required for synthesis of wybutosine; a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; Belongs to the TYW3 family
Top 10 interactors (score): PPM2 (0.999); TRM12 (0.999); TYW1 (0.996); TRM5 (0.993); PPM1 (0.887); TRM2 (0.77); LTP1 (0.749); RIT1 (0.749); TAD3 (0.67); TAD1 (0.666); TAD2 (0.623); MOD5 (0.592); GCD1 (0.583); PUS7 (0.579); SUA5 (0.553); TRM7 (0.535); RQC2 (0.518); PCL7 (0.495); MTQ2 (0.495); CAP2 (0.481)
Homologues (species, bitscore): TYW3 (Homo sapiens, 99.0); Tyw3 (Mus musculus, 108.6); tyw3 (Danio rerio, 92.4); tyw3 (Xenopus tropicalis, 93.6); AT4G04670 (Arabidopsis thaliana, 127.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:407851-408672:+ | gene-YGL050W_AKU4011 | rna-NM_001180915.3_AKU4011 | cds-NP_011465.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:167457-168278:- | gene-YGL050W_BG1 | rna-NM_001180915.3_BG1 | cds-NP_011465.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:408420-409241:+ | gene-YGL050W_Bruggeman | rna-NM_001180915.3_Bruggeman | cds-NP_011465.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:406833-407654:+ | gene-YGL050W_CAT1 | rna-NM_001180915.3_CAT1 | cds-NP_011465.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:409314-410135:+ | gene-YGL050W_CBS1585 | rna-NM_001180915.3_CBS1585 | cds-NP_011465.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:403440-404261:+ | gene-YGL050W_CBS436 | rna-NM_001180915.3_CBS436 | cds-NP_011465.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:401494-402315:+ | gene-YGL050W_CBS6412 | rna-NM_001180915.3_CBS6412 | cds-NP_011465.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:405531-406352:+ | gene-YGL050W_CBS6413 | rna-NM_001180915.3_CBS6413 | cds-NP_011465.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:405618-406439:+ | gene-YGL050W_CENPK1137D | rna-NM_001180915.3_CENPK1137D | cds-NP_011465.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:396227-397048:+ | gene-YGL050W_EthanolRed | rna-NM_001180915.3_EthanolRed | cds-NP_011465.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:399490-400311:+ | gene-YGL050W_FaliES1 | rna-NM_001180915.3_FaliES1 | cds-NP_011465.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000165.1:16520-17341:- | gene-YGL050W_JAY291 | rna-NM_001180915.3_JAY291 | cds-NP_011465.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:405624-406445:+ | gene-YGL050W_MUCL30387 | rna-NM_001180915.3_MUCL30387 | cds-NP_011465.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:408671-409492:+ | gene-YGL050W_MUCL30388 | rna-NM_001180915.3_MUCL30388 | cds-NP_011465.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:405107-405928:+ | gene-YGL050W_MUCL39482 | rna-NM_001180915.3_MUCL39482 | cds-NP_011465.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:413524-414345:+ | gene-YGL050W_MUCL42920 | rna-NM_001180915.3_MUCL42920 | cds-NP_011465.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:405776-406597:+ | gene-YGL050W_NCIM3186 | rna-NM_001180915.3_NCIM3186 | cds-NP_011465.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:399232-400053:+ | gene-YGL050W_NCYC1407 | rna-NM_001180915.3_NCYC1407 | cds-NP_011465.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:401805-402626:+ | gene-YGL050W_PE2H3 | rna-NM_001180915.3_PE2H3 | cds-NP_011465.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:406855-407676:+ | gene-YGL050W_PE2H4 | rna-NM_001180915.3_PE2H4 | cds-NP_011465.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:405776-406597:+ | gene-YGL050W_S288C | rna-NM_001180915.3_S288C | cds-NP_011465.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:149031-149852:- | gene-YGL050W_SA1 | rna-NM_001180915.3_SA1 | cds-NP_011465.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:418854-419675:+ | gene-YGL050W_ThermosaccDry | rna-NM_001180915.3_ThermosaccDry | cds-NP_011465.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:508800-509621:+ | gene-YGL050W_VR1 | rna-NM_001180915.3_VR1 | cds-NP_011465.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:397096-397917:+ | gene-YGL050W_ZTW1 | rna-NM_001180915.3_ZTW1 | cds-NP_011465.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:406510-407331:+ | gene-YGL050W_Sparadoxus | rna-NM_001180915.3_Sparadoxus | cds-NP_011465.3_Sparadoxus | 87.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |