Gene name: TWF1
Reference locus (S288C): YGR080W
Gene biotype: protein_coding
Description: Twinfilin-1; Twinfilin; highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton; coordinates actin filament severing and monomer sequestering at sites of rapid actin turnover; composed of two cofilin-like regions, stimulates actin depolymerization as does the mouse homolog, mTwf1
Top 10 interactors (score): ACT1 (0.999); COF1 (0.991); SRV2 (0.986); AIM7 (0.983); PFY1 (0.967); ABP1 (0.96); CRN1 (0.948); SAC6 (0.944); CAP2 (0.931); LAS17 (0.906); AIP1 (0.9); ARP2 (0.897); VRP1 (0.846); ARC19 (0.77); ARC40 (0.764); ARP3 (0.715); TPM1 (0.711); YNR021W (0.705); TPM2 (0.645); BZZ1 (0.642)
Homologues (species, bitscore): TWF2 (Homo sapiens, 85.5); Twf2 (Mus musculus, 88.2); twf2b (Danio rerio, 82.0); wdr82 (Xenopus tropicalis, 76.3); twf (Drosophila melanogaster, 75.5); F38E9.5 (Caenorhabditis elegans, 76.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:625694-626692:+ | gene-YGR080W_AKU4011 | rna-NM_001181209.3_AKU4011 | cds-NP_011594.3_AKU4011 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:61965-62963:+ | gene-YGR080W_BG1 | rna-NM_001181209.3_BG1 | cds-NP_011594.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:627963-628961:+ | gene-YGR080W_Bruggeman | rna-NM_001181209.3_Bruggeman | cds-NP_011594.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:626402-627400:+ | gene-YGR080W_CAT1 | rna-NM_001181209.3_CAT1 | cds-NP_011594.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:626975-627973:+ | gene-YGR080W_CBS1585 | rna-NM_001181209.3_CBS1585 | cds-NP_011594.3_CBS1585 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:628321-629319:+ | gene-YGR080W_CBS436 | rna-NM_001181209.3_CBS436 | cds-NP_011594.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:619820-620818:+ | gene-YGR080W_CBS6412 | rna-NM_001181209.3_CBS6412 | cds-NP_011594.3_CBS6412 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:623621-624619:+ | gene-YGR080W_CBS6413 | rna-NM_001181209.3_CBS6413 | cds-NP_011594.3_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:641696-642694:+ | gene-YGR080W_CENPK1137D | rna-NM_001181209.3_CENPK1137D | cds-NP_011594.3_CENPK1137D | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:613947-614945:+ | gene-YGR080W_EthanolRed | rna-NM_001181209.3_EthanolRed | cds-NP_011594.3_EthanolRed | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:617412-618410:+ | gene-YGR080W_FaliES1 | rna-NM_001181209.3_FaliES1 | cds-NP_011594.3_FaliES1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000435.1:68355-69353:+ | gene-YGR080W_JAY291 | rna-NM_001181209.3_JAY291 | cds-NP_011594.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:624639-625637:+ | gene-YGR080W_MUCL30387 | rna-NM_001181209.3_MUCL30387 | cds-NP_011594.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:628007-629005:+ | gene-YGR080W_MUCL30388 | rna-NM_001181209.3_MUCL30388 | cds-NP_011594.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:622839-623837:+ | gene-YGR080W_MUCL39482 | rna-NM_001181209.3_MUCL39482 | cds-NP_011594.3_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:632639-633637:+ | gene-YGR080W_MUCL42920 | rna-NM_001181209.3_MUCL42920 | cds-NP_011594.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:642010-643008:+ | gene-YGR080W_NCIM3186 | rna-NM_001181209.3_NCIM3186 | cds-NP_011594.3_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:617015-618013:+ | gene-YGR080W_NCYC1407 | rna-NM_001181209.3_NCYC1407 | cds-NP_011594.3_NCYC1407 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:620259-621257:+ | gene-YGR080W_PE2H3 | rna-NM_001181209.3_PE2H3 | cds-NP_011594.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:625379-626377:+ | gene-YGR080W_PE2H4 | rna-NM_001181209.3_PE2H4 | cds-NP_011594.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:642010-643008:+ | gene-YGR080W_S288C | rna-NM_001181209.3_S288C | cds-NP_011594.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:68583-69581:+ | gene-YGR080W_SA1 | rna-NM_001181209.3_SA1 | cds-NP_011594.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:636723-637721:+ | gene-YGR080W_ThermosaccDry | rna-NM_001181209.3_ThermosaccDry | cds-NP_011594.3_ThermosaccDry | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:733704-734702:+ | gene-YGR080W_VR1 | rna-NM_001181209.3_VR1 | cds-NP_011594.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:92206-93204:+ | gene-YGR080W_ZTW1 | rna-NM_001181209.3_ZTW1 | cds-NP_011594.3_ZTW1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:627306-628304:+ | gene-YGR080W_Sparadoxus | rna-NM_001181209.3_Sparadoxus | cds-NP_011594.3_Sparadoxus | 89.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |