Gene name: TUS1
Reference locus (S288C): YLR425W
Gene biotype: protein_coding
Description: Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity; involved in the cell integrity signaling pathway; interacts with Rgl1p; localization of Tus1p to the bed neck is regulated by Rgl1p; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate
Top 10 interactors (score): RHO1 (0.998); ROM1 (0.951); LRG1 (0.912); RHO2 (0.89); ACK1 (0.884); BNI1 (0.866); ROM2 (0.853); PKC1 (0.831); SAC7 (0.823); RGL1 (0.806); FKS1 (0.787); CDC42 (0.781); HOF1 (0.776); SLT2 (0.768); GSC2 (0.757); ACT1 (0.731); IPP1 (0.724); BUD4 (0.724); CYK3 (0.713); RHO3 (0.697)
Homologues (species, bitscore): ITSN2 (Homo sapiens, 55.1); Itsn2 (Mus musculus, 54.3); plekhg5 (Xenopus tropicalis, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:921153-925076:+ | gene-YLR425W_AKU4011 | rna-NM_001182313.3_AKU4011 | cds-NP_013529.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:153642-157565:+ | gene-YLR425W_BG1 | rna-NM_001182313.3_BG1 | cds-NP_013529.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:959456-963379:+ | gene-YLR425W_Bruggeman | rna-NM_001182313.3_Bruggeman | cds-NP_013529.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:955478-959401:+ | gene-YLR425W_CAT1 | rna-NM_001182313.3_CAT1 | cds-NP_013529.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:956750-960673:+ | gene-YLR425W_CBS1585 | rna-NM_001182313.3_CBS1585 | cds-NP_013529.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:946091-950014:+ | gene-YLR425W_CBS436 | rna-NM_001182313.3_CBS436 | cds-NP_013529.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:992790-996713:+ | gene-YLR425W_CBS6412 | rna-NM_001182313.3_CBS6412 | cds-NP_013529.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:957532-961455:+ | gene-YLR425W_CBS6413 | rna-NM_001182313.3_CBS6413 | cds-NP_013529.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:967511-971439:+ | gene-YLR425W_CENPK1137D | rna-NM_001182313.3_CENPK1137D | cds-NP_013529.3_CENPK1137D | 99.6 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:914180-918103:+ | gene-YLR425W_EthanolRed | rna-NM_001182313.3_EthanolRed | cds-NP_013529.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:949451-953374:+ | gene-YLR425W_FaliES1 | rna-NM_001182313.3_FaliES1 | cds-NP_013529.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:65312-69235:- | gene-YLR425W_JAY291 | rna-NM_001182313.3_JAY291 | cds-NP_013529.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:958317-962240:+ | gene-YLR425W_MUCL30387 | rna-NM_001182313.3_MUCL30387 | cds-NP_013529.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:965675-969598:+ | gene-YLR425W_MUCL30388 | rna-NM_001182313.3_MUCL30388 | cds-NP_013529.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:957970-961893:+ | gene-YLR425W_MUCL39482 | rna-NM_001182313.3_MUCL39482 | cds-NP_013529.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:958466-962389:+ | gene-YLR425W_MUCL42920 | rna-NM_001182313.3_MUCL42920 | cds-NP_013529.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:982868-986791:+ | gene-YLR425W_NCIM3186 | rna-NM_001182313.3_NCIM3186 | cds-NP_013529.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:967149-971072:+ | gene-YLR425W_NCYC1407 | rna-NM_001182313.3_NCYC1407 | cds-NP_013529.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:953852-957775:+ | gene-YLR425W_PE2H3 | rna-NM_001182313.3_PE2H3 | cds-NP_013529.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:953596-957519:+ | gene-YLR425W_PE2H4 | rna-NM_001182313.3_PE2H4 | cds-NP_013529.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:982894-986817:+ | gene-YLR425W_S288C | rna-NM_001182313.3_S288C | cds-NP_013529.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:73144-77067:- | gene-YLR425W_SA1 | rna-NM_001182313.3_SA1 | cds-NP_013529.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:952530-956453:+ | gene-YLR425W_ThermosaccDry | rna-NM_001182313.3_ThermosaccDry | cds-NP_013529.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:958957-962880:+ | gene-YLR425W_VR1 | rna-NM_001182313.3_VR1 | cds-NP_013529.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:282805-286727:+ | gene-YLR425W_ZTW1 | rna-NM_001182313.3_ZTW1 | cds-NP_013529.3_ZTW1 | 99.5 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:931952-935875:+ | gene-YLR425W_Sparadoxus | rna-NM_001182313.3_Sparadoxus | cds-NP_013529.3_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |