Gene name: TUL1
Reference locus (S288C): YKL034W
Gene biotype: protein_coding
Description: Transmembrane E3 ubiquitin-protein ligase 1; Subunit of the DSC ubiquitin ligase complex; golgi-localized RING-finger ubiquitin ligase (E3) involved in sorting polar transmembrane domain containing membrane proteins to multivesicular bodies for delivery to the vacuole; proposed involvement in the quality control of misfolded TMD containing proteins; ortholog of fission yeast dsc1
Top 10 interactors (score): DSC2 (0.999); UBX3 (0.996); DSC3 (0.928); RSP5 (0.903); CDC48 (0.889); HRD1 (0.878); TLG1 (0.862); DER1 (0.845); SSH4 (0.845); BSD2 (0.844); YKL031W (0.841); PIB1 (0.829); YPR109W (0.828); VPS4 (0.794); SSM4 (0.763); PPN1 (0.749); SNA3 (0.744); SAN1 (0.74); PEP12 (0.719); CPS1 (0.713)
Homologues (species, bitscore): AT2G20650 (Arabidopsis thaliana, 157.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:357840-360116:+ | gene-YKL034W_AKU4011 | rna-NM_001179600.1_AKU4011 | cds-NP_012890.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:283862-286138:- | gene-YKL034W_BG1 | rna-NM_001179600.1_BG1 | cds-NP_012890.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:377112-379388:+ | gene-YKL034W_Bruggeman | rna-NM_001179600.1_Bruggeman | cds-NP_012890.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:373298-375574:+ | gene-YKL034W_CAT1 | rna-NM_001179600.1_CAT1 | cds-NP_012890.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:370567-372843:+ | gene-YKL034W_CBS1585 | rna-NM_001179600.1_CBS1585 | cds-NP_012890.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:368691-370967:+ | gene-YKL034W_CBS436 | rna-NM_001179600.1_CBS436 | cds-NP_012890.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:354704-356980:+ | gene-YKL034W_CBS6412 | rna-NM_001179600.1_CBS6412 | cds-NP_012890.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:370532-372808:+ | gene-YKL034W_CBS6413 | rna-NM_001179600.1_CBS6413 | cds-NP_012890.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:371487-373763:+ | gene-YKL034W_CENPK1137D | rna-NM_001179600.1_CENPK1137D | cds-NP_012890.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:368521-370797:+ | gene-YKL034W_EthanolRed | rna-NM_001179600.1_EthanolRed | cds-NP_012890.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:369341-371617:+ | gene-YKL034W_FaliES1 | rna-NM_001179600.1_FaliES1 | cds-NP_012890.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000080.1:74262-76538:+ | gene-YKL034W_JAY291 | rna-NM_001179600.1_JAY291 | cds-NP_012890.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:378020-380296:+ | gene-YKL034W_MUCL30387 | rna-NM_001179600.1_MUCL30387 | cds-NP_012890.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:373652-375928:+ | gene-YKL034W_MUCL30388 | rna-NM_001179600.1_MUCL30388 | cds-NP_012890.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:369863-372139:+ | gene-YKL034W_MUCL39482 | rna-NM_001179600.1_MUCL39482 | cds-NP_012890.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:374721-376997:+ | gene-YKL034W_MUCL42920 | rna-NM_001179600.1_MUCL42920 | cds-NP_012890.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:371818-374094:+ | gene-YKL034W_NCIM3186 | rna-NM_001179600.1_NCIM3186 | cds-NP_012890.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:370062-372338:+ | gene-YKL034W_NCYC1407 | rna-NM_001179600.1_NCYC1407 | cds-NP_012890.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:394608-396884:+ | gene-YKL034W_PE2H3 | rna-NM_001179600.1_PE2H3 | cds-NP_012890.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:379343-381619:+ | gene-YKL034W_PE2H4 | rna-NM_001179600.1_PE2H4 | cds-NP_012890.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:371829-374105:+ | gene-YKL034W_S288C | rna-NM_001179600.1_S288C | cds-NP_012890.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:49949-52225:+ | gene-YKL034W_SA1 | rna-NM_001179600.1_SA1 | cds-NP_012890.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:370527-372803:+ | gene-YKL034W_ThermosaccDry | rna-NM_001179600.1_ThermosaccDry | cds-NP_012890.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:369676-371952:+ | gene-YKL034W_VR1 | rna-NM_001179600.1_VR1 | cds-NP_012890.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:368551-370827:+ | gene-YKL034W_ZTW1 | rna-NM_001179600.1_ZTW1 | cds-NP_012890.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:387778-390054:+ | gene-YKL034W_Sparadoxus | rna-NM_001179600.1_Sparadoxus | cds-NP_012890.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |