TUB3 (YML124C)


Gene profile

Gene name: TUB3
Reference locus (S288C): YML124C
Gene biotype: protein_coding

Description: Tubulin alpha-3 chain; Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication

Top 10 interactors (score): TUB2 (0.999); PAC2 (0.999); BIM1 (0.998); DYN1 (0.997); STU2 (0.986); ALF1 (0.986); CIN1 (0.985); CIN8 (0.982); RBL2 (0.981); HHT2 (0.971); ACT1 (0.97); BIK1 (0.965); KAR3 (0.961); HHT1 (0.96); TUB1 (0.96); CDC31 (0.952); MAD2 (0.949); TDH2 (0.939); TDH1 (0.938); TDH3 (0.927)

Homologues (species, bitscore): TUBA1C (Homo sapiens, 713.4); Tuba1c (Mus musculus, 713.8); tuba8l2 (Danio rerio, 715.7); tuba1c (Xenopus tropicalis, 715.7); tubA84B (Drosophila melanogaster, 716.1); tba-1 (Caenorhabditis elegans, 708.4); TUA6 (Arabidopsis thaliana, 667.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:15746-17381:- gene-YML124C_AKU4011 rna-NM_001182487.1_AKU4011 cds-NP_013582.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:458876-460511:+ gene-YML124C_BG1 rna-NM_001182487.1_BG1 cds-NP_013582.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:22001-23636:- gene-YML124C_Bruggeman rna-NM_001182487.1_Bruggeman cds-NP_013582.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:23567-25202:- gene-YML124C_CAT1 rna-NM_001182487.1_CAT1 cds-NP_013582.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:15746-17381:- gene-YML124C_CBS1585 rna-NM_001182487.1_CBS1585 cds-NP_013582.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:21761-23396:- gene-YML124C_CBS436 rna-NM_001182487.1_CBS436 cds-NP_013582.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:16508-18143:- gene-YML124C_CBS6412 rna-NM_001182487.1_CBS6412 cds-NP_013582.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:14972-16607:- gene-YML124C_CBS6413 rna-NM_001182487.1_CBS6413 cds-NP_013582.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:16565-18200:- gene-YML124C_CENPK1137D rna-NM_001182487.1_CENPK1137D cds-NP_013582.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:16259-17894:- gene-YML124C_EthanolRed rna-NM_001182487.1_EthanolRed cds-NP_013582.1_EthanolRed 99.4 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:16536-18171:- gene-YML124C_FaliES1 rna-NM_001182487.1_FaliES1 cds-NP_013582.1_FaliES1 99.4 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000345.1:72056-73691:+ gene-YML124C_JAY291 rna-NM_001182487.1_JAY291 cds-NP_013582.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:20024-21659:- gene-YML124C_MUCL30387 rna-NM_001182487.1_MUCL30387 cds-NP_013582.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:23442-25077:- gene-YML124C_MUCL30388 rna-NM_001182487.1_MUCL30388 cds-NP_013582.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:15800-17435:- gene-YML124C_MUCL39482 rna-NM_001182487.1_MUCL39482 cds-NP_013582.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:19469-21104:- gene-YML124C_MUCL42920 rna-NM_001182487.1_MUCL42920 cds-NP_013582.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:22002-23637:- gene-YML124C_NCIM3186 rna-NM_001182487.1_NCIM3186 cds-NP_013582.1_NCIM3186 99.1 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:16555-18190:- gene-YML124C_NCYC1407 rna-NM_001182487.1_NCYC1407 cds-NP_013582.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:21949-23584:- gene-YML124C_PE2H3 rna-NM_001182487.1_PE2H3 cds-NP_013582.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:21887-23522:- gene-YML124C_PE2H4 rna-NM_001182487.1_PE2H4 cds-NP_013582.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:22048-23683:- gene-YML124C_S288C rna-NM_001182487.1_S288C cds-NP_013582.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000054.1:13862-15497:- gene-YML124C_SA1 rna-NM_001182487.1_SA1 cds-NP_013582.1_SA1 99.3 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:15834-17469:- gene-YML124C_ThermosaccDry rna-NM_001182487.1_ThermosaccDry cds-NP_013582.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:20238-21873:- gene-YML124C_VR1 rna-NM_001182487.1_VR1 cds-NP_013582.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000026.1:15024-16659:- gene-YML124C_ZTW1 rna-NM_001182487.1_ZTW1 cds-NP_013582.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:26921-28553:- gene-YML124C_Sparadoxus rna-NM_001182487.1_Sparadoxus cds-NP_013582.1_Sparadoxus 91.1 100.0 Verified 1 1 1 False True False False False

Additional files