TUB2 (YFL037W)


Gene profile

Gene name: TUB2
Reference locus (S288C): YFL037W
Gene biotype: protein_coding

Description: Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules; mutation in human ortholog is associated with congenital fibrosis of the extraocular muscles (CFEOM) with polymicrogyria

Top 10 interactors (score): BIM1 (0.999); TUB1 (0.999); STU2 (0.999); DYN1 (0.999); TUB3 (0.999); CIN8 (0.997); RBL2 (0.997); KIP1 (0.995); ACT1 (0.994); KAR3 (0.991); CIN1 (0.991); MAD2 (0.988); STU1 (0.987); SMY1 (0.985); CMD1 (0.985); RHO1 (0.975); PAC2 (0.972); SEC4 (0.966); KIP3 (0.966); SPC98 (0.952)

Homologues (species, bitscore): TUBB4B (Homo sapiens, 737.6); Tubb4b (Mus musculus, 737.6); zgc:123194 (Danio rerio, 743.4); tubb3 (Xenopus tropicalis, 738.4); betaTub85D (Drosophila melanogaster, 734.6); ben-1 (Caenorhabditis elegans, 737.3); TUB6 (Arabidopsis thaliana, 719.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:52671-54044:+ gene-YFL037W_AKU4011 rna-NM_001179929.1_AKU4011 cds-NP_116616.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000182.1:15744-17117:- gene-YFL037W_BG1 rna-NM_001179929.1_BG1 cds-NP_116616.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:51555-52928:+ gene-YFL037W_Bruggeman rna-NM_001179929.1_Bruggeman cds-NP_116616.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:56440-57813:+ gene-YFL037W_CAT1 rna-NM_001179929.1_CAT1 cds-NP_116616.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:53349-54722:+ gene-YFL037W_CBS1585 rna-NM_001179929.1_CBS1585 cds-NP_116616.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:26987-28360:+ gene-YFL037W_CBS436 rna-NM_001179929.1_CBS436 cds-NP_116616.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:53588-54960:+ gene-YFL037W_CBS6412 rna-NM_001179929.1_CBS6412 cds-NP_116616.1_CBS6412 94.4 98.1 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:55747-57120:+ gene-YFL037W_CBS6413 rna-NM_001179929.1_CBS6413 cds-NP_116616.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:52661-54034:+ gene-YFL037W_CENPK1137D rna-NM_001179929.1_CENPK1137D cds-NP_116616.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:52014-53387:+ gene-YFL037W_EthanolRed rna-NM_001179929.1_EthanolRed cds-NP_116616.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:53223-54596:+ gene-YFL037W_FaliES1 rna-NM_001179929.1_FaliES1 cds-NP_116616.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000448.1:61680-63053:+ gene-YFL037W_JAY291 rna-NM_001179929.1_JAY291 cds-NP_116616.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:53641-55014:+ gene-YFL037W_MUCL30387 rna-NM_001179929.1_MUCL30387 cds-NP_116616.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:51549-52922:+ gene-YFL037W_MUCL30388 rna-NM_001179929.1_MUCL30388 cds-NP_116616.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:51865-53238:+ gene-YFL037W_MUCL39482 rna-NM_001179929.1_MUCL39482 cds-NP_116616.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:49571-50944:+ gene-YFL037W_MUCL42920 rna-NM_001179929.1_MUCL42920 cds-NP_116616.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:56335-57708:+ gene-YFL037W_NCIM3186 rna-NM_001179929.1_NCIM3186 cds-NP_116616.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:52936-54309:+ gene-YFL037W_NCYC1407 rna-NM_001179929.1_NCYC1407 cds-NP_116616.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:72835-74208:+ gene-YFL037W_PE2H3 rna-NM_001179929.1_PE2H3 cds-NP_116616.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:72386-73759:+ gene-YFL037W_PE2H4 rna-NM_001179929.1_PE2H4 cds-NP_116616.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:56336-57709:+ gene-YFL037W_S288C rna-NM_001179929.1_S288C cds-NP_116616.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:277927-279300:- gene-YFL037W_SA1 rna-NM_001179929.1_SA1 cds-NP_116616.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:52411-53784:+ gene-YFL037W_ThermosaccDry rna-NM_001179929.1_ThermosaccDry cds-NP_116616.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:60961-62334:+ gene-YFL037W_VR1 rna-NM_001179929.1_VR1 cds-NP_116616.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000012.1:37707-39080:+ gene-YFL037W_ZTW1 rna-NM_001179929.1_ZTW1 cds-NP_116616.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:76756-78129:+ gene-YFL037W_Sparadoxus rna-NM_001179929.1_Sparadoxus cds-NP_116616.1_Sparadoxus 94.3 100.0 Verified 1 1 1 True True False False False

Additional files