TUB1 (YML085C)


Gene profile

Gene name: TUB1
Reference locus (S288C): YML085C
Gene biotype: protein_coding

Description: Tubulin alpha-1 chain; Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication

Top 10 interactors (score): PAC2 (0.999); TUB2 (0.999); DYN1 (0.998); BIM1 (0.998); STU2 (0.998); ALF1 (0.986); ACT1 (0.979); KAR3 (0.974); KIP3 (0.96); HHT2 (0.96); TUB3 (0.96); HHT1 (0.96); CDC31 (0.96); RBL2 (0.959); SPC98 (0.952); CIN8 (0.947); SPC97 (0.945); TDH1 (0.938); TDH2 (0.938); NDC80 (0.938)

Homologues (species, bitscore): TUBA4A (Homo sapiens, 728.0); Tuba4a (Mus musculus, 728.0); tuba8l2 (Danio rerio, 728.4); tuba4b (Xenopus tropicalis, 730.7); tubA84B (Drosophila melanogaster, 723.8); tba-2 (Caenorhabditis elegans, 719.2); TUA6 (Arabidopsis thaliana, 677.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:91662-93122:- gene-YML085C_AKU4011 rna-NM_001182444.1_AKU4011 cds-NP_013625.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:383003-384463:+ gene-YML085C_BG1 rna-NM_001182444.1_BG1 cds-NP_013625.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:97834-99294:- gene-YML085C_Bruggeman rna-NM_001182444.1_Bruggeman cds-NP_013625.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:99511-100971:- gene-YML085C_CAT1 rna-NM_001182444.1_CAT1 cds-NP_013625.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:91667-93127:- gene-YML085C_CBS1585 rna-NM_001182444.1_CBS1585 cds-NP_013625.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:97605-99065:- gene-YML085C_CBS436 rna-NM_001182444.1_CBS436 cds-NP_013625.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:92379-93839:- gene-YML085C_CBS6412 rna-NM_001182444.1_CBS6412 cds-NP_013625.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:90852-92312:- gene-YML085C_CBS6413 rna-NM_001182444.1_CBS6413 cds-NP_013625.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:92653-94113:- gene-YML085C_CENPK1137D rna-NM_001182444.1_CENPK1137D cds-NP_013625.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:91939-93398:- gene-YML085C_EthanolRed rna-NM_001182444.1_EthanolRed cds-NP_013625.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:92448-93907:- gene-YML085C_FaliES1 rna-NM_001182444.1_FaliES1 cds-NP_013625.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000366.1:63195-64655:+ gene-YML085C_JAY291 rna-NM_001182444.1_JAY291 cds-NP_013625.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:96358-97818:- gene-YML085C_MUCL30387 rna-NM_001182444.1_MUCL30387 cds-NP_013625.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:99506-100966:- gene-YML085C_MUCL30388 rna-NM_001182444.1_MUCL30388 cds-NP_013625.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:91678-93138:- gene-YML085C_MUCL39482 rna-NM_001182444.1_MUCL39482 cds-NP_013625.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:96416-97876:- gene-YML085C_MUCL42920 rna-NM_001182444.1_MUCL42920 cds-NP_013625.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:97895-99354:- gene-YML085C_NCIM3186 rna-NM_001182444.1_NCIM3186 cds-NP_013625.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:92477-93937:- gene-YML085C_NCYC1407 rna-NM_001182444.1_NCYC1407 cds-NP_013625.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:97842-99302:- gene-YML085C_PE2H3 rna-NM_001182444.1_PE2H3 cds-NP_013625.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:97780-99240:- gene-YML085C_PE2H4 rna-NM_001182444.1_PE2H4 cds-NP_013625.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:97941-99400:- gene-YML085C_S288C rna-NM_001182444.1_S288C cds-NP_013625.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000041.1:84861-86321:+ gene-YML085C_SA1 rna-NM_001182444.1_SA1 cds-NP_013625.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:91740-93199:- gene-YML085C_ThermosaccDry rna-NM_001182444.1_ThermosaccDry cds-NP_013625.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:96131-97591:- gene-YML085C_VR1 rna-NM_001182444.1_VR1 cds-NP_013625.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:71275-72732:- gene-YML085C_ZTW1 rna-NM_001182444.1_ZTW1 cds-NP_013625.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:102460-103914:- gene-YML085C_Sparadoxus rna-NM_001182444.1_Sparadoxus cds-NP_013625.1_Sparadoxus 94.3 100.0 Verified 1 1 1 True True False False False

Additional files