TTI1 (YKL033W)


Gene profile

Gene name: TTI1
Reference locus (S288C): YKL033W
Gene biotype: protein_coding

Description: TEL2-interacting protein 1; Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1; similar to S. pombe Tti1p; detected in highly purified mitochondria in high-throughput studies

Top 10 interactors (score): RVB2 (0.999); TEL2 (0.999); RVB1 (0.999); TRA1 (0.999); TTI2 (0.997); ASA1 (0.986); TOR1 (0.98); TOR2 (0.944); LST8 (0.934); HSC82 (0.931); PIH1 (0.925); TAH1 (0.908); HSP82 (0.885); YKL031W (0.862); KOG1 (0.812); TSC11 (0.804); TEL1 (0.754); MEC1 (0.748); SPC3 (0.739); KCS1 (0.724)

Homologues (species, bitscore): TTI1 (Homo sapiens, 77.8); Tti1 (Mus musculus, 77.0); tti1 (Danio rerio, 51.6); tti1 (Xenopus tropicalis, 65.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:361467-364583:+ gene-YKL033W_AKU4011 rna-NM_001179599.1_AKU4011 cds-NP_012892.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:279399-282515:- gene-YKL033W_BG1 rna-NM_001179599.1_BG1 cds-NP_012892.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:381887-385003:+ gene-YKL033W_Bruggeman rna-NM_001179599.1_Bruggeman cds-NP_012892.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:376921-380037:+ gene-YKL033W_CAT1 rna-NM_001179599.1_CAT1 cds-NP_012892.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:374194-377310:+ gene-YKL033W_CBS1585 rna-NM_001179599.1_CBS1585 cds-NP_012892.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:372316-375432:+ gene-YKL033W_CBS436 rna-NM_001179599.1_CBS436 cds-NP_012892.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:358331-361447:+ gene-YKL033W_CBS6412 rna-NM_001179599.1_CBS6412 cds-NP_012892.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:374159-377275:+ gene-YKL033W_CBS6413 rna-NM_001179599.1_CBS6413 cds-NP_012892.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:375114-378230:+ gene-YKL033W_CENPK1137D rna-NM_001179599.1_CENPK1137D cds-NP_012892.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:372147-375263:+ gene-YKL033W_EthanolRed rna-NM_001179599.1_EthanolRed cds-NP_012892.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:372968-376084:+ gene-YKL033W_FaliES1 rna-NM_001179599.1_FaliES1 cds-NP_012892.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000080.1:77885-81001:+ gene-YKL033W_JAY291 rna-NM_001179599.1_JAY291 cds-NP_012892.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:381647-384763:+ gene-YKL033W_MUCL30387 rna-NM_001179599.1_MUCL30387 cds-NP_012892.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:377280-380396:+ gene-YKL033W_MUCL30388 rna-NM_001179599.1_MUCL30388 cds-NP_012892.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:373490-376606:+ gene-YKL033W_MUCL39482 rna-NM_001179599.1_MUCL39482 cds-NP_012892.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:378349-381465:+ gene-YKL033W_MUCL42920 rna-NM_001179599.1_MUCL42920 cds-NP_012892.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:375445-378561:+ gene-YKL033W_NCIM3186 rna-NM_001179599.1_NCIM3186 cds-NP_012892.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:373689-376805:+ gene-YKL033W_NCYC1407 rna-NM_001179599.1_NCYC1407 cds-NP_012892.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:398231-401347:+ gene-YKL033W_PE2H3 rna-NM_001179599.1_PE2H3 cds-NP_012892.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:382966-386082:+ gene-YKL033W_PE2H4 rna-NM_001179599.1_PE2H4 cds-NP_012892.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:375456-378572:+ gene-YKL033W_S288C rna-NM_001179599.1_S288C cds-NP_012892.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:53572-56688:+ gene-YKL033W_SA1 rna-NM_001179599.1_SA1 cds-NP_012892.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:374153-377269:+ gene-YKL033W_ThermosaccDry rna-NM_001179599.1_ThermosaccDry cds-NP_012892.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:373299-376415:+ gene-YKL033W_VR1 rna-NM_001179599.1_VR1 cds-NP_012892.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:372178-375294:+ gene-YKL033W_ZTW1 rna-NM_001179599.1_ZTW1 cds-NP_012892.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:391392-394493:+ gene-YKL033W_Sparadoxus rna-NM_001179599.1_Sparadoxus cds-NP_012892.1_Sparadoxus 87.4 99.5 Verified 1 1 1 False True False False False

Additional files