Gene name: TSR1
Reference locus (S288C): YDL060W
Gene biotype: protein_coding
Description: Ribosome biogenesis protein TSR1; Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p; relocalizes from nucleus to cytoplasm upon DNA replication stress; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily
Top 10 interactors (score): UTP13 (0.999); YTM1 (0.999); LTV1 (0.999); KRI1 (0.999); NOP58 (0.999); HAS1 (0.999); DBP8 (0.999); RRP12 (0.999); IMP4 (0.999); UTP18 (0.999); NOP7 (0.999); ENP2 (0.999); PWP2 (0.999); ERB1 (0.999); NAN1 (0.999); PRP43 (0.999); ROK1 (0.999); MRD1 (0.999); UTP15 (0.999); DIP2 (0.999)
Homologues (species, bitscore): TSR1 (Homo sapiens, 328.6); Tsr1 (Mus musculus, 341.3); tsr1 (Danio rerio, 328.6); tsr1 (Xenopus tropicalis, 282.3); CG7338 (Drosophila melanogaster, 360.1); tag-151 (Caenorhabditis elegans, 328.6); AT1G42440 (Arabidopsis thaliana, 275.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:326206-328572:+ | gene-YDL060W_AKU4011 | rna-NM_001180119.1_AKU4011 | cds-NP_010223.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:221464-223830:- | gene-YDL060W_BG1 | rna-NM_001180119.1_BG1 | cds-NP_010223.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:343998-346364:+ | gene-YDL060W_Bruggeman | rna-NM_001180119.1_Bruggeman | cds-NP_010223.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:340358-342724:+ | gene-YDL060W_CAT1 | rna-NM_001180119.1_CAT1 | cds-NP_010223.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:324459-326825:+ | gene-YDL060W_CBS1585 | rna-NM_001180119.1_CBS1585 | cds-NP_010223.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:341169-343535:+ | gene-YDL060W_CBS436 | rna-NM_001180119.1_CBS436 | cds-NP_010223.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:322554-324920:+ | gene-YDL060W_CBS6412 | rna-NM_001180119.1_CBS6412 | cds-NP_010223.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:342545-344911:+ | gene-YDL060W_CBS6413 | rna-NM_001180119.1_CBS6413 | cds-NP_010223.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:340439-342805:+ | gene-YDL060W_CENPK1137D | rna-NM_001180119.1_CENPK1137D | cds-NP_010223.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:337009-339375:+ | gene-YDL060W_EthanolRed | rna-NM_001180119.1_EthanolRed | cds-NP_010223.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:343256-345622:+ | gene-YDL060W_FaliES1 | rna-NM_001180119.1_FaliES1 | cds-NP_010223.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:113282-115648:+ | gene-YDL060W_JAY291 | rna-NM_001180119.1_JAY291 | cds-NP_010223.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:341389-343755:+ | gene-YDL060W_MUCL30387 | rna-NM_001180119.1_MUCL30387 | cds-NP_010223.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:332515-334881:+ | gene-YDL060W_MUCL30388 | rna-NM_001180119.1_MUCL30388 | cds-NP_010223.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:325570-327936:+ | gene-YDL060W_MUCL39482 | rna-NM_001180119.1_MUCL39482 | cds-NP_010223.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:247584-249950:+ | gene-YDL060W_MUCL42920 | rna-NM_001180119.1_MUCL42920 | cds-NP_010223.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:341542-343908:+ | gene-YDL060W_NCIM3186 | rna-NM_001180119.1_NCIM3186 | cds-NP_010223.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:325594-327960:+ | gene-YDL060W_NCYC1407 | rna-NM_001180119.1_NCYC1407 | cds-NP_010223.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:332401-334767:+ | gene-YDL060W_PE2H3 | rna-NM_001180119.1_PE2H3 | cds-NP_010223.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:332401-334767:+ | gene-YDL060W_PE2H4 | rna-NM_001180119.1_PE2H4 | cds-NP_010223.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:341619-343985:+ | gene-YDL060W_S288C | rna-NM_001180119.1_S288C | cds-NP_010223.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:90949-93315:- | gene-YDL060W_SA1 | rna-NM_001180119.1_SA1 | cds-NP_010223.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:342708-345074:+ | gene-YDL060W_ThermosaccDry | rna-NM_001180119.1_ThermosaccDry | cds-NP_010223.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:345289-347655:+ | gene-YDL060W_VR1 | rna-NM_001180119.1_VR1 | cds-NP_010223.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:340641-343008:+ | gene-YDL060W_ZTW1 | rna-NM_001180119.1_ZTW1 | cds-NP_010223.1_ZTW1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:342775-345141:+ | gene-YDL060W_Sparadoxus | rna-NM_001180119.1_Sparadoxus | cds-NP_010223.1_Sparadoxus | 89.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |