TSC11 (YER093C)


Gene profile

Gene name: TSC11
Reference locus (S288C): YER093C
Gene biotype: protein_coding

Description: Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p); TORC2 is a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain; Belongs to the RICTOR family

Top 10 interactors (score): AVO1 (0.999); AVO2 (0.999); LST8 (0.999); TOR2 (0.999); TOR1 (0.999); BIT61 (0.997); YPK1 (0.996); KOG1 (0.996); SCH9 (0.99); SLM1 (0.986); BIT2 (0.984); YPK2 (0.966); RHB1 (0.936); TCO89 (0.926); CDC53 (0.911); PKH1 (0.858); ECM25 (0.848); FPR1 (0.848); TEP1 (0.838); GTR1 (0.819)

Homologues (species, bitscore): RICTOR (Homo sapiens, 233.8); Rictor (Mus musculus, 225.3); rictorb (Danio rerio, 220.3); rictor (Xenopus tropicalis, 224.6); rictor (Drosophila melanogaster, 115.2); rict-1 (Caenorhabditis elegans, 70.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:337092-341384:- gene-YER093C_AKU4011 rna-NM_001178984.1_AKU4011 cds-NP_011018.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:84451-88743:+ gene-YER093C_BG1 rna-NM_001178984.1_BG1 cds-NP_011018.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:346652-350944:- gene-YER093C_Bruggeman rna-NM_001178984.1_Bruggeman cds-NP_011018.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:341006-345298:- gene-YER093C_CAT1 rna-NM_001178984.1_CAT1 cds-NP_011018.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:336957-341249:- gene-YER093C_CBS1585 rna-NM_001178984.1_CBS1585 cds-NP_011018.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:339062-343354:- gene-YER093C_CBS436 rna-NM_001178984.1_CBS436 cds-NP_011018.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:336413-340705:- gene-YER093C_CBS6412 rna-NM_001178984.1_CBS6412 cds-NP_011018.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:342403-346695:- gene-YER093C_CBS6413 rna-NM_001178984.1_CBS6413 cds-NP_011018.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:341230-345522:- gene-YER093C_CENPK1137D rna-NM_001178984.1_CENPK1137D cds-NP_011018.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:337435-341727:- gene-YER093C_EthanolRed rna-NM_001178984.1_EthanolRed cds-NP_011018.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:337880-342172:- gene-YER093C_FaliES1 rna-NM_001178984.1_FaliES1 cds-NP_011018.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000153.1:52940-57232:- gene-YER093C_JAY291 rna-NM_001178984.1_JAY291 cds-NP_011018.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:342047-346339:- gene-YER093C_MUCL30387 rna-NM_001178984.1_MUCL30387 cds-NP_011018.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:337721-342013:- gene-YER093C_MUCL30388 rna-NM_001178984.1_MUCL30388 cds-NP_011018.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:335981-340273:- gene-YER093C_MUCL39482 rna-NM_001178984.1_MUCL39482 cds-NP_011018.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:343186-347478:- gene-YER093C_MUCL42920 rna-NM_001178984.1_MUCL42920 cds-NP_011018.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:343319-347611:- gene-YER093C_NCIM3186 rna-NM_001178984.1_NCIM3186 cds-NP_011018.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:341044-345336:- gene-YER093C_NCYC1407 rna-NM_001178984.1_NCYC1407 cds-NP_011018.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:351695-355987:- gene-YER093C_PE2H3 rna-NM_001178984.1_PE2H3 cds-NP_011018.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:341636-345928:- gene-YER093C_PE2H4 rna-NM_001178984.1_PE2H4 cds-NP_011018.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:343320-347612:- gene-YER093C_S288C rna-NM_001178984.1_S288C cds-NP_011018.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000023.1:52938-57230:- gene-YER093C_SA1 rna-NM_001178984.1_SA1 cds-NP_011018.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:338677-342969:- gene-YER093C_ThermosaccDry rna-NM_001178984.1_ThermosaccDry cds-NP_011018.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:339337-343629:- gene-YER093C_VR1 rna-NM_001178984.1_VR1 cds-NP_011018.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:335835-340127:- gene-YER093C_ZTW1 rna-NM_001178984.1_ZTW1 cds-NP_011018.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:339257-343549:- gene-YER093C_Sparadoxus rna-NM_001178984.1_Sparadoxus cds-NP_011018.1_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files