Gene name: TSC10
Reference locus (S288C): YBR265W
Gene biotype: protein_coding
Description: 3-ketodihydrosphingosine reductase TSC10; 3-ketosphinganine reductase; catalyzes the second step in phytosphingosine synthesis; essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine; localized to lipid droplets; member of short chain dehydrogenase/reductase protein family
Top 10 interactors (score): LCB2 (0.997); LCB1 (0.994); LAC1 (0.987); SUR2 (0.986); LAG1 (0.985); YDC1 (0.955); YDL114W (0.953); LCB4 (0.94); LCB3 (0.94); LCB5 (0.923); YSR3 (0.909); TSC3 (0.869); UTP5 (0.844); CSG2 (0.826); SCS7 (0.825); ENV9 (0.818); GAA1 (0.78); GPI10 (0.763); DPL1 (0.729); AUR1 (0.711)
Homologues (species, bitscore): KDSR (Homo sapiens, 75.9); Kdsr (Mus musculus, 66.6); kdsr (Danio rerio, 74.3); kdsr (Xenopus tropicalis, 76.6); CG10425 (Drosophila melanogaster, 63.9); Y37E11AM.3 (Caenorhabditis elegans, 80.5); TSC10B (Arabidopsis thaliana, 73.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:722865-723827:+ | gene-YBR265W_AKU4011 | rna-NM_001178613.2_AKU4011 | cds-NP_009824.2_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:93889-94851:+ | gene-YBR265W_BG1 | rna-NM_001178613.2_BG1 | cds-NP_009824.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:724029-724991:+ | gene-YBR265W_Bruggeman | rna-NM_001178613.2_Bruggeman | cds-NP_009824.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:727755-728717:+ | gene-YBR265W_CAT1 | rna-NM_001178613.2_CAT1 | cds-NP_009824.2_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:714431-715393:+ | gene-YBR265W_CBS1585 | rna-NM_001178613.2_CBS1585 | cds-NP_009824.2_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:720876-721838:+ | gene-YBR265W_CBS436 | rna-NM_001178613.2_CBS436 | cds-NP_009824.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:809046-810008:+ | gene-YBR265W_CBS6412 | rna-NM_001178613.2_CBS6412 | cds-NP_009824.2_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:720479-721441:+ | gene-YBR265W_CBS6413 | rna-NM_001178613.2_CBS6413 | cds-NP_009824.2_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:732489-733451:+ | gene-YBR265W_CENPK1137D | rna-NM_001178613.2_CENPK1137D | cds-NP_009824.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:845900-846862:+ | gene-YBR265W_EthanolRed | rna-NM_001178613.2_EthanolRed | cds-NP_009824.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:739247-740209:+ | gene-YBR265W_FaliES1 | rna-NM_001178613.2_FaliES1 | cds-NP_009824.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:63847-64809:- | gene-YBR265W_JAY291 | rna-NM_001178613.2_JAY291 | cds-NP_009824.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:726072-727034:+ | gene-YBR265W_MUCL30387 | rna-NM_001178613.2_MUCL30387 | cds-NP_009824.2_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:743153-744115:+ | gene-YBR265W_MUCL30388 | rna-NM_001178613.2_MUCL30388 | cds-NP_009824.2_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:712738-713700:+ | gene-YBR265W_MUCL39482 | rna-NM_001178613.2_MUCL39482 | cds-NP_009824.2_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:722609-723571:+ | gene-YBR265W_MUCL42920 | rna-NM_001178613.2_MUCL42920 | cds-NP_009824.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:738379-739341:+ | gene-YBR265W_NCIM3186 | rna-NM_001178613.2_NCIM3186 | cds-NP_009824.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:714627-715589:+ | gene-YBR265W_NCYC1407 | rna-NM_001178613.2_NCYC1407 | cds-NP_009824.2_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:737757-738719:+ | gene-YBR265W_PE2H3 | rna-NM_001178613.2_PE2H3 | cds-NP_009824.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:735433-736395:+ | gene-YBR265W_PE2H4 | rna-NM_001178613.2_PE2H4 | cds-NP_009824.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:738582-739544:+ | gene-YBR265W_S288C | rna-NM_001178613.2_S288C | cds-NP_009824.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:93710-94672:+ | gene-YBR265W_SA1 | rna-NM_001178613.2_SA1 | cds-NP_009824.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:738239-739201:+ | gene-YBR265W_ThermosaccDry | rna-NM_001178613.2_ThermosaccDry | cds-NP_009824.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:718455-719417:+ | gene-YBR265W_VR1 | rna-NM_001178613.2_VR1 | cds-NP_009824.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:711084-712046:+ | gene-YBR265W_ZTW1 | rna-NM_001178613.2_ZTW1 | cds-NP_009824.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:754991-755953:+ | gene-YBR265W_Sparadoxus | rna-NM_001178613.2_Sparadoxus | cds-NP_009824.2_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |