Gene name: TSA2
Reference locus (S288C): YDR453C
Gene biotype: protein_coding
Description: Peroxiredoxin TSA2; Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants; protein abundance increases in response to DNA replication stress; TSA2 has a paralog, TSA1, that arose from the whole genome duplication; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily
Top 10 interactors (score): TRR1 (0.981); SRX1 (0.98); DOT5 (0.974); AHP1 (0.972); SEC4 (0.965); TRR2 (0.959); CTT1 (0.946); TRX2 (0.938); GPX1 (0.928); HYR1 (0.899); TSA1 (0.892); GPX2 (0.891); YAP1 (0.887); CTA1 (0.867); ECM4 (0.863); GLR1 (0.848); GRX1 (0.844); SOD1 (0.838); TRX1 (0.835); SOD2 (0.828)
Homologues (species, bitscore): PRDX2 (Homo sapiens, 250.8); Prdx2 (Mus musculus, 253.4); prdx2 (Danio rerio, 243.8); prdx2 (Xenopus tropicalis, 243.0); Jafrac1 (Drosophila melanogaster, 229.9); prdx-2 (Caenorhabditis elegans, 246.5); AT3G11630 (Arabidopsis thaliana, 188.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1304978-1305568:- | gene-YDR453C_AKU4011 | rna-NM_001180761.1_AKU4011 | cds-NP_010741.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:183336-183926:- | gene-YDR453C_BG1 | rna-NM_001180761.1_BG1 | cds-NP_010741.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1336409-1336999:- | gene-YDR453C_Bruggeman | rna-NM_001180761.1_Bruggeman | cds-NP_010741.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1313559-1314149:- | gene-YDR453C_CAT1 | rna-NM_001180761.1_CAT1 | cds-NP_010741.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1299284-1299874:- | gene-YDR453C_CBS1585 | rna-NM_001180761.1_CBS1585 | cds-NP_010741.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1318657-1319247:- | gene-YDR453C_CBS436 | rna-NM_001180761.1_CBS436 | cds-NP_010741.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1294913-1295503:- | gene-YDR453C_CBS6412 | rna-NM_001180761.1_CBS6412 | cds-NP_010741.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1317924-1318514:- | gene-YDR453C_CBS6413 | rna-NM_001180761.1_CBS6413 | cds-NP_010741.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1363746-1364336:- | gene-YDR453C_CENPK1137D | rna-NM_001180761.1_CENPK1137D | cds-NP_010741.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1308334-1308924:- | gene-YDR453C_EthanolRed | rna-NM_001180761.1_EthanolRed | cds-NP_010741.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1311887-1312477:- | gene-YDR453C_FaliES1 | rna-NM_001180761.1_FaliES1 | cds-NP_010741.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:10145-10735:- | gene-YDR453C_JAY291 | rna-NM_001180761.1_JAY291 | cds-NP_010741.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1318899-1319489:- | gene-YDR453C_MUCL30387 | rna-NM_001180761.1_MUCL30387 | cds-NP_010741.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1300926-1301516:- | gene-YDR453C_MUCL30388 | rna-NM_001180761.1_MUCL30388 | cds-NP_010741.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1290768-1291358:- | gene-YDR453C_MUCL39482 | rna-NM_001180761.1_MUCL39482 | cds-NP_010741.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1233567-1234157:- | gene-YDR453C_MUCL42920 | rna-NM_001180761.1_MUCL42920 | cds-NP_010741.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1364995-1365585:- | gene-YDR453C_NCIM3186 | rna-NM_001180761.1_NCIM3186 | cds-NP_010741.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1304541-1305131:- | gene-YDR453C_NCYC1407 | rna-NM_001180761.1_NCYC1407 | cds-NP_010741.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1315394-1315984:- | gene-YDR453C_PE2H3 | rna-NM_001180761.1_PE2H3 | cds-NP_010741.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1320951-1321541:- | gene-YDR453C_PE2H4 | rna-NM_001180761.1_PE2H4 | cds-NP_010741.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1365072-1365662:- | gene-YDR453C_S288C | rna-NM_001180761.1_S288C | cds-NP_010741.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:251502-252092:+ | gene-YDR453C_SA1 | rna-NM_001180761.1_SA1 | cds-NP_010741.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1316109-1316699:- | gene-YDR453C_ThermosaccDry | rna-NM_001180761.1_ThermosaccDry | cds-NP_010741.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1331845-1332435:- | gene-YDR453C_VR1 | rna-NM_001180761.1_VR1 | cds-NP_010741.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:358785-359375:- | gene-YDR453C_ZTW1 | rna-NM_001180761.1_ZTW1 | cds-NP_010741.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1319202-1319792:- | gene-YDR453C_Sparadoxus | rna-NM_001180761.1_Sparadoxus | cds-NP_010741.1_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |