Gene name: TRX2
Reference locus (S288C): YGR209C
Gene biotype: protein_coding
Description: Thioredoxin-2; Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication
Top 10 interactors (score): TRX1 (0.999); TRR1 (0.995); AHP1 (0.995); TSA1 (0.992); MXR1 (0.979); GLR1 (0.977); GRX2 (0.973); YAP1 (0.972); TRR2 (0.971); GRX1 (0.964); PRX1 (0.943); TSA2 (0.938); GSH1 (0.936); GPX2 (0.936); SOD1 (0.929); SKN7 (0.91); SRX1 (0.902); HYR1 (0.902); MET16 (0.898); GPX1 (0.877)
Homologues (species, bitscore): TXN (Homo sapiens, 105.5); Txn1 (Mus musculus, 100.9); zgc:56493 (Danio rerio, 98.2); txn (Xenopus tropicalis, 109.0); Trx-2 (Drosophila melanogaster, 99.4); png-1 (Caenorhabditis elegans, 100.1); TRX2 (Arabidopsis thaliana, 96.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:878432-878746:- | gene-YGR209C_AKU4011 | rna-NM_001181338.3_AKU4011 | cds-NP_011725.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:158813-159127:- | gene-YGR209C_BG1 | rna-NM_001181338.3_BG1 | cds-NP_011725.3_BG1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:886631-886945:- | gene-YGR209C_Bruggeman | rna-NM_001181338.3_Bruggeman | cds-NP_011725.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:884624-884938:- | gene-YGR209C_CAT1 | rna-NM_001181338.3_CAT1 | cds-NP_011725.3_CAT1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:881870-882184:- | gene-YGR209C_CBS1585 | rna-NM_001181338.3_CBS1585 | cds-NP_011725.3_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:885221-885535:- | gene-YGR209C_CBS436 | rna-NM_001181338.3_CBS436 | cds-NP_011725.3_CBS436 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:872742-873056:- | gene-YGR209C_CBS6412 | rna-NM_001181338.3_CBS6412 | cds-NP_011725.3_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:878801-879115:- | gene-YGR209C_CBS6413 | rna-NM_001181338.3_CBS6413 | cds-NP_011725.3_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:912625-912939:- | gene-YGR209C_CENPK1137D | rna-NM_001181338.3_CENPK1137D | cds-NP_011725.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:867251-867565:- | gene-YGR209C_EthanolRed | rna-NM_001181338.3_EthanolRed | cds-NP_011725.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:871642-871956:- | gene-YGR209C_FaliES1 | rna-NM_001181338.3_FaliES1 | cds-NP_011725.3_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000148.1:29366-29680:- | gene-YGR209C_JAY291 | rna-NM_001181338.3_JAY291 | cds-NP_011725.3_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:884116-884430:- | gene-YGR209C_MUCL30387 | rna-NM_001181338.3_MUCL30387 | cds-NP_011725.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:883800-884114:- | gene-YGR209C_MUCL30388 | rna-NM_001181338.3_MUCL30388 | cds-NP_011725.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:876946-877260:- | gene-YGR209C_MUCL39482 | rna-NM_001181338.3_MUCL39482 | cds-NP_011725.3_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:894492-894806:- | gene-YGR209C_MUCL42920 | rna-NM_001181338.3_MUCL42920 | cds-NP_011725.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:912913-913227:- | gene-YGR209C_NCIM3186 | rna-NM_001181338.3_NCIM3186 | cds-NP_011725.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:872602-872916:- | gene-YGR209C_NCYC1407 | rna-NM_001181338.3_NCYC1407 | cds-NP_011725.3_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:897208-897522:- | gene-YGR209C_PE2H3 | rna-NM_001181338.3_PE2H3 | cds-NP_011725.3_PE2H3 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:902318-902632:- | gene-YGR209C_PE2H4 | rna-NM_001181338.3_PE2H4 | cds-NP_011725.3_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:912913-913227:- | gene-YGR209C_S288C | rna-NM_001181338.3_S288C | cds-NP_011725.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:88164-88478:+ | gene-YGR209C_SA1 | rna-NM_001181338.3_SA1 | cds-NP_011725.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:892153-892467:- | gene-YGR209C_ThermosaccDry | rna-NM_001181338.3_ThermosaccDry | cds-NP_011725.3_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:996636-996950:- | gene-YGR209C_VR1 | rna-NM_001181338.3_VR1 | cds-NP_011725.3_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:193595-193909:- | gene-YGR209C_ZTW1 | rna-NM_001181338.3_ZTW1 | cds-NP_011725.3_ZTW1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:884070-884384:- | gene-YGR209C_Sparadoxus | rna-NM_001181338.3_Sparadoxus | cds-NP_011725.3_Sparadoxus | 93.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |