TRS20 (YBR254C)


Gene profile

Gene name: TRS20
Reference locus (S288C): YBR254C
Gene biotype: protein_coding

Description: Core component of transport protein particle (TRAPP) complexes I-III; TRAPPs are multimeric guanine nucleotide-exchange factors for GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); mutation leads to defects in endocytic recycling, block in sporulation/meiosis; mutations in human homolog TRAPPC2 cause spondyloepiphyseal dysplasia tarda, TRAPPC2 can complement yeast null mutant

Top 10 interactors (score): TRS23 (0.999); TRS31 (0.999); TRS33 (0.999); TRS85 (0.999); BET3 (0.999); BET5 (0.999); TRS130 (0.999); TRS120 (0.999); TRS65 (0.998); TCA17 (0.994); YPT1 (0.99); MRS6 (0.939); SEC23 (0.936); YKT6 (0.916); GDI1 (0.911); SEC22 (0.904); YPT31 (0.897); YPT32 (0.849); SEC13 (0.841); SEC31 (0.835)

Homologues (species, bitscore): TRAPPC2 (Homo sapiens, 102.1); Trappc2 (Mus musculus, 100.1); trappc2 (Danio rerio, 100.5); trappc2 (Xenopus tropicalis, 99.4); Trs20 (Drosophila melanogaster, 97.4); sedl-1 (Caenorhabditis elegans, 97.1); AT1G80500 (Arabidopsis thaliana, 99.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:708021-708548:- gene-YBR254C_AKU4011 rna-NM_001178602.1_AKU4011 cds-NP_009813.1_AKU4011 99.2 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:79042-79569:- gene-YBR254C_BG1 rna-NM_001178602.1_BG1 cds-NP_009813.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:709183-709710:- gene-YBR254C_Bruggeman rna-NM_001178602.1_Bruggeman cds-NP_009813.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:712937-713464:- gene-YBR254C_CAT1 rna-NM_001178602.1_CAT1 cds-NP_009813.1_CAT1 99.4 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:699587-700114:- gene-YBR254C_CBS1585 rna-NM_001178602.1_CBS1585 cds-NP_009813.1_CBS1585 99.2 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:706032-706559:- gene-YBR254C_CBS436 rna-NM_001178602.1_CBS436 cds-NP_009813.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:794202-794729:- gene-YBR254C_CBS6412 rna-NM_001178602.1_CBS6412 cds-NP_009813.1_CBS6412 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:705635-706162:- gene-YBR254C_CBS6413 rna-NM_001178602.1_CBS6413 cds-NP_009813.1_CBS6413 99.2 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:717644-718171:- gene-YBR254C_CENPK1137D rna-NM_001178602.1_CENPK1137D cds-NP_009813.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:831058-831585:- gene-YBR254C_EthanolRed rna-NM_001178602.1_EthanolRed cds-NP_009813.1_EthanolRed 99.2 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:724405-724932:- gene-YBR254C_FaliES1 rna-NM_001178602.1_FaliES1 cds-NP_009813.1_FaliES1 99.2 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:79123-79650:+ gene-YBR254C_JAY291 rna-NM_001178602.1_JAY291 cds-NP_009813.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:711226-711753:- gene-YBR254C_MUCL30387 rna-NM_001178602.1_MUCL30387 cds-NP_009813.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:728309-728836:- gene-YBR254C_MUCL30388 rna-NM_001178602.1_MUCL30388 cds-NP_009813.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:697894-698421:- gene-YBR254C_MUCL39482 rna-NM_001178602.1_MUCL39482 cds-NP_009813.1_MUCL39482 99.2 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:707762-708289:- gene-YBR254C_MUCL42920 rna-NM_001178602.1_MUCL42920 cds-NP_009813.1_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:723533-724060:- gene-YBR254C_NCIM3186 rna-NM_001178602.1_NCIM3186 cds-NP_009813.1_NCIM3186 99.2 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:699783-700310:- gene-YBR254C_NCYC1407 rna-NM_001178602.1_NCYC1407 cds-NP_009813.1_NCYC1407 99.2 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:722915-723442:- gene-YBR254C_PE2H3 rna-NM_001178602.1_PE2H3 cds-NP_009813.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:720591-721118:- gene-YBR254C_PE2H4 rna-NM_001178602.1_PE2H4 cds-NP_009813.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:723736-724263:- gene-YBR254C_S288C rna-NM_001178602.1_S288C cds-NP_009813.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:78863-79390:- gene-YBR254C_SA1 rna-NM_001178602.1_SA1 cds-NP_009813.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:723397-723924:- gene-YBR254C_ThermosaccDry rna-NM_001178602.1_ThermosaccDry cds-NP_009813.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:703610-704137:- gene-YBR254C_VR1 rna-NM_001178602.1_VR1 cds-NP_009813.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:696243-696770:- gene-YBR254C_ZTW1 rna-NM_001178602.1_ZTW1 cds-NP_009813.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:740160-740687:- gene-YBR254C_Sparadoxus rna-NM_001178602.1_Sparadoxus cds-NP_009813.1_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files