Gene name: TRR1
Reference locus (S288C): YDR353W
Gene biotype: protein_coding
Description: Cytoplasmic thioredoxin reductase; key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress; protein abundance increases in response to DNA replication stress; TRR1 has a paralog, TRR2, that arose from the whole genome duplication; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
Top 10 interactors (score): TRR2 (0.999); TSA1 (0.996); TRX1 (0.996); TRX2 (0.995); GLR1 (0.983); TSA2 (0.981); TRX3 (0.979); YAP1 (0.961); GSH1 (0.943); CYS3 (0.928); SKN7 (0.919); SRX1 (0.916); PRX1 (0.899); GPX2 (0.897); CTT1 (0.896); GRX2 (0.886); HYR1 (0.883); AHP1 (0.882); CTA1 (0.882); GPX1 (0.862)
Homologues (species, bitscore): NTRB (Arabidopsis thaliana, 417.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1129363-1130322:+ | gene-YDR353W_AKU4011 | rna-NM_001180661.1_AKU4011 | cds-NP_010640.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:7911-8870:+ | gene-YDR353W_BG1 | rna-NM_001180661.1_BG1 | cds-NP_010640.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1160016-1160975:+ | gene-YDR353W_Bruggeman | rna-NM_001180661.1_Bruggeman | cds-NP_010640.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1138605-1139564:+ | gene-YDR353W_CAT1 | rna-NM_001180661.1_CAT1 | cds-NP_010640.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1124080-1125039:+ | gene-YDR353W_CBS1585 | rna-NM_001180661.1_CBS1585 | cds-NP_010640.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1142662-1143621:+ | gene-YDR353W_CBS436 | rna-NM_001180661.1_CBS436 | cds-NP_010640.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1120340-1121299:+ | gene-YDR353W_CBS6412 | rna-NM_001180661.1_CBS6412 | cds-NP_010640.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1142230-1143189:+ | gene-YDR353W_CBS6413 | rna-NM_001180661.1_CBS6413 | cds-NP_010640.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1181945-1182904:+ | gene-YDR353W_CENPK1137D | rna-NM_001180661.1_CENPK1137D | cds-NP_010640.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1133765-1134724:+ | gene-YDR353W_EthanolRed | rna-NM_001180661.1_EthanolRed | cds-NP_010640.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1137048-1138007:+ | gene-YDR353W_FaliES1 | rna-NM_001180661.1_FaliES1 | cds-NP_010640.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:53065-54024:- | gene-YDR353W_JAY291 | rna-NM_001180661.1_JAY291 | cds-NP_010640.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1143314-1144273:+ | gene-YDR353W_MUCL30387 | rna-NM_001180661.1_MUCL30387 | cds-NP_010640.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1125920-1126879:+ | gene-YDR353W_MUCL30388 | rna-NM_001180661.1_MUCL30388 | cds-NP_010640.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1115614-1116573:+ | gene-YDR353W_MUCL39482 | rna-NM_001180661.1_MUCL39482 | cds-NP_010640.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1057548-1058507:+ | gene-YDR353W_MUCL42920 | rna-NM_001180661.1_MUCL42920 | cds-NP_010640.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1183222-1184181:+ | gene-YDR353W_NCIM3186 | rna-NM_001180661.1_NCIM3186 | cds-NP_010640.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1129287-1130246:+ | gene-YDR353W_NCYC1407 | rna-NM_001180661.1_NCYC1407 | cds-NP_010640.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1139714-1140673:+ | gene-YDR353W_PE2H3 | rna-NM_001180661.1_PE2H3 | cds-NP_010640.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1145299-1146258:+ | gene-YDR353W_PE2H4 | rna-NM_001180661.1_PE2H4 | cds-NP_010640.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1183299-1184258:+ | gene-YDR353W_S288C | rna-NM_001180661.1_S288C | cds-NP_010640.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:7992-8951:+ | gene-YDR353W_SA1 | rna-NM_001180661.1_SA1 | cds-NP_010640.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1141329-1142288:+ | gene-YDR353W_ThermosaccDry | rna-NM_001180661.1_ThermosaccDry | cds-NP_010640.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:568678-569637:+ | gene-YDR353W_VR1 | rna-NM_001180661.1_VR1 | cds-NP_010640.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:184165-185124:+ | gene-YDR353W_ZTW1 | rna-NM_001180661.1_ZTW1 | cds-NP_010640.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1135245-1136204:+ | gene-YDR353W_Sparadoxus | rna-NM_001180661.1_Sparadoxus | cds-NP_010640.1_Sparadoxus | 93.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |