Gene name: TRM82
Reference locus (S288C): YDR165W
Gene biotype: protein_coding
Description: Catalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p; relocalizes to the cytosol in response to hypoxia; mutation in human ortholog WDR4 causes microcephalic primordial dwarfism
Top 10 interactors (score): TRM11 (0.999); TRM8 (0.999); GCD14 (0.999); GCD10 (0.998); TRM112 (0.99); RTT10 (0.99); TRM10 (0.99); TRM7 (0.988); PUF6 (0.985); NIP7 (0.982); NCL1 (0.975); PWP2 (0.973); TAD3 (0.972); UTP6 (0.97); ARX1 (0.967); ERB1 (0.965); NOP1 (0.964); DBP9 (0.959); RRB1 (0.958); TRM5 (0.956)
Homologues (species, bitscore): WDR4 (Homo sapiens, 87.4); Wdr4 (Mus musculus, 97.1); wdr4 (Danio rerio, 89.7); wuho (Drosophila melanogaster, 82.8); Y102E9.2 (Caenorhabditis elegans, 68.9); TRM82 (Arabidopsis thaliana, 66.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:756167-757501:+ | gene-YDR165W_AKU4011 | rna-NM_001180472.1_AKU4011 | cds-NP_010449.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:369254-370588:- | gene-YDR165W_BG1 | rna-NM_001180472.1_BG1 | cds-NP_010449.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:787664-788998:+ | gene-YDR165W_Bruggeman | rna-NM_001180472.1_Bruggeman | cds-NP_010449.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:774939-776273:+ | gene-YDR165W_CAT1 | rna-NM_001180472.1_CAT1 | cds-NP_010449.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:746534-747868:+ | gene-YDR165W_CBS1585 | rna-NM_001180472.1_CBS1585 | cds-NP_010449.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:772727-774061:+ | gene-YDR165W_CBS436 | rna-NM_001180472.1_CBS436 | cds-NP_010449.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:741984-743318:+ | gene-YDR165W_CBS6412 | rna-NM_001180472.1_CBS6412 | cds-NP_010449.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:770432-771766:+ | gene-YDR165W_CBS6413 | rna-NM_001180472.1_CBS6413 | cds-NP_010449.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:785533-786867:+ | gene-YDR165W_CENPK1137D | rna-NM_001180472.1_CENPK1137D | cds-NP_010449.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:755993-757327:+ | gene-YDR165W_EthanolRed | rna-NM_001180472.1_EthanolRed | cds-NP_010449.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:764205-765539:+ | gene-YDR165W_FaliES1 | rna-NM_001180472.1_FaliES1 | cds-NP_010449.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000119.1:16723-18057:- | gene-YDR165W_JAY291 | rna-NM_001180472.1_JAY291 | cds-NP_010449.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:773042-774376:+ | gene-YDR165W_MUCL30387 | rna-NM_001180472.1_MUCL30387 | cds-NP_010449.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:761552-762886:+ | gene-YDR165W_MUCL30388 | rna-NM_001180472.1_MUCL30388 | cds-NP_010449.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:747962-749296:+ | gene-YDR165W_MUCL39482 | rna-NM_001180472.1_MUCL39482 | cds-NP_010449.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:685786-687120:+ | gene-YDR165W_MUCL42920 | rna-NM_001180472.1_MUCL42920 | cds-NP_010449.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:784794-786128:+ | gene-YDR165W_NCIM3186 | rna-NM_001180472.1_NCIM3186 | cds-NP_010449.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:747365-748699:+ | gene-YDR165W_NCYC1407 | rna-NM_001180472.1_NCYC1407 | cds-NP_010449.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:766559-767893:+ | gene-YDR165W_PE2H3 | rna-NM_001180472.1_PE2H3 | cds-NP_010449.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:765864-767198:+ | gene-YDR165W_PE2H4 | rna-NM_001180472.1_PE2H4 | cds-NP_010449.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:784871-786205:+ | gene-YDR165W_S288C | rna-NM_001180472.1_S288C | cds-NP_010449.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:132070-133404:+ | gene-YDR165W_SA1 | rna-NM_001180472.1_SA1 | cds-NP_010449.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:762340-763674:+ | gene-YDR165W_ThermosaccDry | rna-NM_001180472.1_ThermosaccDry | cds-NP_010449.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:777328-778662:+ | gene-YDR165W_VR1 | rna-NM_001180472.1_VR1 | cds-NP_010449.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:25091-26425:+ | gene-YDR165W_ZTW1 | rna-NM_001180472.1_ZTW1 | cds-NP_010449.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:768556-769890:+ | gene-YDR165W_Sparadoxus | rna-NM_001180472.1_Sparadoxus | cds-NP_010449.1_Sparadoxus | 87.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |