Gene name: TRM732
Reference locus (S288C): YMR259C
Gene biotype: protein_coding
Description: tRNA (cytidine(32)-2'-O)-methyltransferase non-catalytic subunit TRM732; Protein involved in 2'-O-methylation of C32 of substrate tRNAs; interacts with 2'-O-ribose methyltransferase Trm7p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene; yeast null mutant can be functionally complemented by human THADA, mutations in which have been implicated in epithelial thyroid adenomas, type 2 diabetes, and polycystic ovary syndrome (PCOS)
Top 10 interactors (score): TRM7 (0.999); RTT10 (0.984); UTP21 (0.923); TRM82 (0.918); SDA1 (0.913); MDN1 (0.9); TRM8 (0.897); IKI3 (0.892); TRM11 (0.889); TRM10 (0.887); GCD14 (0.887); RRP5 (0.872); NCL1 (0.867); GCD10 (0.864); TRM44 (0.846); MRM2 (0.84); TAD3 (0.839); CDC123 (0.822); TRM9 (0.82); TAD2 (0.815)
Homologues (species, bitscore): THADA (Homo sapiens, 138.3); Thada (Mus musculus, 132.1); thada (Xenopus tropicalis, 130.2); CG15618 (Drosophila melanogaster, 76.3); Y92H12A.5 (Caenorhabditis elegans, 62.8); AT3G55160 (Arabidopsis thaliana, 94.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:824061-828323:- | gene-YMR259C_AKU4011 | rna-NM_001182766.1_AKU4011 | cds-NP_013986.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:126080-130342:+ | gene-YMR259C_BG1 | rna-NM_001182766.1_BG1 | cds-NP_013986.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:769289-773551:- | gene-YMR259C_Bruggeman | rna-NM_001182766.1_Bruggeman | cds-NP_013986.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:772311-776573:- | gene-YMR259C_CAT1 | rna-NM_001182766.1_CAT1 | cds-NP_013986.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:756311-760573:- | gene-YMR259C_CBS1585 | rna-NM_001182766.1_CBS1585 | cds-NP_013986.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:761332-765594:- | gene-YMR259C_CBS436 | rna-NM_001182766.1_CBS436 | cds-NP_013986.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:867875-872137:- | gene-YMR259C_CBS6412 | rna-NM_001182766.1_CBS6412 | cds-NP_013986.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:755422-759684:- | gene-YMR259C_CBS6413 | rna-NM_001182766.1_CBS6413 | cds-NP_013986.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:778990-783290:- | gene-YMR259C_CENPK1137D | rna-NM_001182766.1_CENPK1137D | cds-NP_013986.1_CENPK1137D | 98.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:816765-821027:- | gene-YMR259C_EthanolRed | rna-NM_001182766.1_EthanolRed | cds-NP_013986.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:762792-767054:- | gene-YMR259C_FaliES1 | rna-NM_001182766.1_FaliES1 | cds-NP_013986.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:19479-23740:+ | gene-YMR259C_JAY291 | rna-NM_001182766.1_JAY291 | cds-NP_013986.1_JAY291 | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:763138-767400:- | gene-YMR259C_MUCL30387 | rna-NM_001182766.1_MUCL30387 | cds-NP_013986.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:771731-775993:- | gene-YMR259C_MUCL30388 | rna-NM_001182766.1_MUCL30388 | cds-NP_013986.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:757399-761661:- | gene-YMR259C_MUCL39482 | rna-NM_001182766.1_MUCL39482 | cds-NP_013986.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:765466-769728:- | gene-YMR259C_MUCL42920 | rna-NM_001182766.1_MUCL42920 | cds-NP_013986.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:784575-788837:- | gene-YMR259C_NCIM3186 | rna-NM_001182766.1_NCIM3186 | cds-NP_013986.1_NCIM3186 | 96.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:757032-761294:- | gene-YMR259C_NCYC1407 | rna-NM_001182766.1_NCYC1407 | cds-NP_013986.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:767031-771293:- | gene-YMR259C_PE2H3 | rna-NM_001182766.1_PE2H3 | cds-NP_013986.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:768077-772339:- | gene-YMR259C_PE2H4 | rna-NM_001182766.1_PE2H4 | cds-NP_013986.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:784621-788883:- | gene-YMR259C_S288C | rna-NM_001182766.1_S288C | cds-NP_013986.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:19552-23814:+ | gene-YMR259C_SA1 | rna-NM_001182766.1_SA1 | cds-NP_013986.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:758961-763223:- | gene-YMR259C_ThermosaccDry | rna-NM_001182766.1_ThermosaccDry | cds-NP_013986.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:771564-775826:- | gene-YMR259C_VR1 | rna-NM_001182766.1_VR1 | cds-NP_013986.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:174155-178417:- | gene-YMR259C_ZTW1 | rna-NM_001182766.1_ZTW1 | cds-NP_013986.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:777344-781603:- | gene-YMR259C_Sparadoxus | rna-NM_001182766.1_Sparadoxus | cds-NP_013986.1_Sparadoxus | 87.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |