Gene name: TRM7
Reference locus (S288C): YBR061C
Gene biotype: protein_coding
Description: 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID); Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily
Top 10 interactors (score): RTT10 (0.999); TRM732 (0.999); NCL1 (0.994); TRM82 (0.988); TRM8 (0.982); TRM10 (0.978); TRM1 (0.978); GCD10 (0.975); PUS7 (0.974); TRM11 (0.973); TRM5 (0.972); DEG1 (0.964); GCD14 (0.964); TRM9 (0.955); PUS1 (0.916); TRM13 (0.911); NOC4 (0.911); TRM44 (0.909); TRM3 (0.899); MOD5 (0.895)
Homologues (species, bitscore): FTSJ1 (Homo sapiens, 283.9); Ftsj1 (Mus musculus, 285.0); ftsj1 (Danio rerio, 297.7); FTSJ3 (Xenopus tropicalis, 145.6); CG5220 (Drosophila melanogaster, 242.3); R74.7 (Caenorhabditis elegans, 272.3); AT5G01230 (Arabidopsis thaliana, 296.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:347204-348136:- | gene-YBR061C_AKU4011 | rna-NM_001178409.3_AKU4011 | cds-NP_009617.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:337461-338393:- | gene-YBR061C_BG1 | rna-NM_001178409.3_BG1 | cds-NP_009617.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:348195-349127:- | gene-YBR061C_Bruggeman | rna-NM_001178409.3_Bruggeman | cds-NP_009617.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:351707-352639:- | gene-YBR061C_CAT1 | rna-NM_001178409.3_CAT1 | cds-NP_009617.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:339485-340417:- | gene-YBR061C_CBS1585 | rna-NM_001178409.3_CBS1585 | cds-NP_009617.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:347562-348494:- | gene-YBR061C_CBS436 | rna-NM_001178409.3_CBS436 | cds-NP_009617.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:437703-438635:- | gene-YBR061C_CBS6412 | rna-NM_001178409.3_CBS6412 | cds-NP_009617.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:344609-345541:- | gene-YBR061C_CBS6413 | rna-NM_001178409.3_CBS6413 | cds-NP_009617.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:358549-359481:- | gene-YBR061C_CENPK1137D | rna-NM_001178409.3_CENPK1137D | cds-NP_009617.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:473972-474904:- | gene-YBR061C_EthanolRed | rna-NM_001178409.3_EthanolRed | cds-NP_009617.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:363250-364182:- | gene-YBR061C_FaliES1 | rna-NM_001178409.3_FaliES1 | cds-NP_009617.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000124.1:11187-12119:- | gene-YBR061C_JAY291 | rna-NM_001178409.3_JAY291 | cds-NP_009617.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:349560-350492:- | gene-YBR061C_MUCL30387 | rna-NM_001178409.3_MUCL30387 | cds-NP_009617.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:349575-350507:- | gene-YBR061C_MUCL30388 | rna-NM_001178409.3_MUCL30388 | cds-NP_009617.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:339473-340405:- | gene-YBR061C_MUCL39482 | rna-NM_001178409.3_MUCL39482 | cds-NP_009617.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:346694-347626:- | gene-YBR061C_MUCL42920 | rna-NM_001178409.3_MUCL42920 | cds-NP_009617.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:364584-365516:- | gene-YBR061C_NCIM3186 | rna-NM_001178409.3_NCIM3186 | cds-NP_009617.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:340391-341323:- | gene-YBR061C_NCYC1407 | rna-NM_001178409.3_NCYC1407 | cds-NP_009617.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:352636-353568:- | gene-YBR061C_PE2H3 | rna-NM_001178409.3_PE2H3 | cds-NP_009617.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:350312-351244:- | gene-YBR061C_PE2H4 | rna-NM_001178409.3_PE2H4 | cds-NP_009617.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:364787-365719:- | gene-YBR061C_S288C | rna-NM_001178409.3_S288C | cds-NP_009617.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:111780-112712:+ | gene-YBR061C_SA1 | rna-NM_001178409.3_SA1 | cds-NP_009617.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:362261-363193:- | gene-YBR061C_ThermosaccDry | rna-NM_001178409.3_ThermosaccDry | cds-NP_009617.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:344254-345186:- | gene-YBR061C_VR1 | rna-NM_001178409.3_VR1 | cds-NP_009617.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:337948-338880:- | gene-YBR061C_ZTW1 | rna-NM_001178409.3_ZTW1 | cds-NP_009617.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:375012-375944:- | gene-YBR061C_Sparadoxus | rna-NM_001178409.3_Sparadoxus | cds-NP_009617.3_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |