Gene name: TRM12
Reference locus (S288C): YML005W
Gene biotype: protein_coding
Description: Trna(phe) (4-demethylwyosine(37)-c(7)) aminocarboxypropyltransferase; tRNA wybutosine-synthesizing protein 2; S-adenosylmethionine-dependent methyltransferase; required for wybutosine formation in phenylalanine-accepting tRNA; member of the seven beta-strand family; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family
Top 10 interactors (score): TYW1 (0.999); TYW3 (0.999); TRM5 (0.991); PPM2 (0.986); MTQ1 (0.955); TSR3 (0.923); TRM10 (0.922); TRM9 (0.899); TRM112 (0.894); TAD1 (0.863); YNL092W (0.86); TRM2 (0.856); EFM3 (0.846); BMT2 (0.842); TAE1 (0.824); TRM11 (0.804); RKM2 (0.791); EFM4 (0.788); TRM44 (0.783); NCL1 (0.763)
Homologues (species, bitscore): TRMT12 (Homo sapiens, 81.3); Trmt12 (Mus musculus, 84.7); zgc:153361 (Danio rerio, 93.6); trmt12 (Xenopus tropicalis, 105.9); AT4G04670 (Arabidopsis thaliana, 92.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:309792-311180:+ | gene-YML005W_AKU4011 | rna-NM_001182360.1_AKU4011 | cds-NP_013709.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:231645-233033:- | gene-YML005W_BG1 | rna-NM_001182360.1_BG1 | cds-NP_013709.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:249762-251150:+ | gene-YML005W_Bruggeman | rna-NM_001182360.1_Bruggeman | cds-NP_013709.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:252273-253661:+ | gene-YML005W_CAT1 | rna-NM_001182360.1_CAT1 | cds-NP_013709.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:242771-244159:+ | gene-YML005W_CBS1585 | rna-NM_001182360.1_CBS1585 | cds-NP_013709.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:248302-249690:+ | gene-YML005W_CBS436 | rna-NM_001182360.1_CBS436 | cds-NP_013709.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:356540-357928:+ | gene-YML005W_CBS6412 | rna-NM_001182360.1_CBS6412 | cds-NP_013709.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:242026-243414:+ | gene-YML005W_CBS6413 | rna-NM_001182360.1_CBS6413 | cds-NP_013709.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:254952-256340:+ | gene-YML005W_CENPK1137D | rna-NM_001182360.1_CENPK1137D | cds-NP_013709.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:242806-244194:+ | gene-YML005W_EthanolRed | rna-NM_001182360.1_EthanolRed | cds-NP_013709.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:245772-247160:+ | gene-YML005W_FaliES1 | rna-NM_001182360.1_FaliES1 | cds-NP_013709.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:189778-191166:- | gene-YML005W_JAY291 | rna-NM_001182360.1_JAY291 | cds-NP_013709.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:247490-248878:+ | gene-YML005W_MUCL30387 | rna-NM_001182360.1_MUCL30387 | cds-NP_013709.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:252155-253543:+ | gene-YML005W_MUCL30388 | rna-NM_001182360.1_MUCL30388 | cds-NP_013709.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:243051-244439:+ | gene-YML005W_MUCL39482 | rna-NM_001182360.1_MUCL39482 | cds-NP_013709.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:248605-249993:+ | gene-YML005W_MUCL42920 | rna-NM_001182360.1_MUCL42920 | cds-NP_013709.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:260175-261563:+ | gene-YML005W_NCIM3186 | rna-NM_001182360.1_NCIM3186 | cds-NP_013709.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:242986-244374:+ | gene-YML005W_NCYC1407 | rna-NM_001182360.1_NCYC1407 | cds-NP_013709.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:248907-250295:+ | gene-YML005W_PE2H3 | rna-NM_001182360.1_PE2H3 | cds-NP_013709.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:255002-256390:+ | gene-YML005W_PE2H4 | rna-NM_001182360.1_PE2H4 | cds-NP_013709.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:260221-261609:+ | gene-YML005W_S288C | rna-NM_001182360.1_S288C | cds-NP_013709.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:276665-278053:- | gene-YML005W_SA1 | rna-NM_001182360.1_SA1 | cds-NP_013709.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:242834-244222:+ | gene-YML005W_ThermosaccDry | rna-NM_001182360.1_ThermosaccDry | cds-NP_013709.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:246794-248182:+ | gene-YML005W_VR1 | rna-NM_001182360.1_VR1 | cds-NP_013709.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:221878-223266:+ | gene-YML005W_ZTW1 | rna-NM_001182360.1_ZTW1 | cds-NP_013709.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:254294-255682:+ | gene-YML005W_Sparadoxus | rna-NM_001182360.1_Sparadoxus | cds-NP_013709.1_Sparadoxus | 86.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |