Gene name: TRM112
Reference locus (S288C): YNR046W
Gene biotype: protein_coding
Description: Multifunctional methyltransferase subunit TRM112; Protein involved in methylation of tRNA, rRNA, and translation factors; also involved in ribosome biogenesis; subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; N7-methylates G1575 of 18S rRNA as complex with Bud23p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; relative distribution to the nucleus increases upon DNA replication stress; functional homolog of human TRMT112
Top 10 interactors (score): MTQ2 (0.999); TRM9 (0.999); TRM11 (0.999); BUD23 (0.999); SUP45 (0.993); TRM82 (0.99); GCD14 (0.989); TRM8 (0.988); ECM16 (0.984); GCD10 (0.98); KTI11 (0.962); PNO1 (0.952); LYS9 (0.95); NOP2 (0.948); SUP35 (0.945); NCS6 (0.944); URM1 (0.942); NIP7 (0.926); NHP2 (0.925); NCS2 (0.919)
Homologues (species, bitscore): TRMT112 (Homo sapiens, 68.9); Trmt112 (Mus musculus, 76.6); trmt112 (Danio rerio, 63.2); trmt112 (Xenopus tropicalis, 64.3); CG12975 (Drosophila melanogaster, 67.4); C04H5.1 (Caenorhabditis elegans, 50.8); AT1G22270 (Arabidopsis thaliana, 69.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:243301-243708:- | gene-YNR046W_AKU4011 | rna-NM_001183223.1_AKU4011 | cds-NP_014444.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:599328-599735:+ | gene-YNR046W_BG1 | rna-NM_001183223.1_BG1 | cds-NP_014444.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:709108-709515:+ | gene-YNR046W_Bruggeman | rna-NM_001183223.1_Bruggeman | cds-NP_014444.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:743079-743486:+ | gene-YNR046W_CAT1 | rna-NM_001183223.1_CAT1 | cds-NP_014444.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:697329-697736:+ | gene-YNR046W_CBS1585 | rna-NM_001183223.1_CBS1585 | cds-NP_014444.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:758872-759279:+ | gene-YNR046W_CBS436 | rna-NM_001183223.1_CBS436 | cds-NP_014444.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:686307-686714:+ | gene-YNR046W_CBS6412 | rna-NM_001183223.1_CBS6412 | cds-NP_014444.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:687992-688399:+ | gene-YNR046W_CBS6413 | rna-NM_001183223.1_CBS6413 | cds-NP_014444.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:701532-701939:+ | gene-YNR046W_CENPK1137D | rna-NM_001183223.1_CENPK1137D | cds-NP_014444.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:692971-693378:+ | gene-YNR046W_EthanolRed | rna-NM_001183223.1_EthanolRed | cds-NP_014444.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:684174-684581:+ | gene-YNR046W_FaliES1 | rna-NM_001183223.1_FaliES1 | cds-NP_014444.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000037.1:18058-18465:- | gene-YNR046W_JAY291 | rna-NM_001183223.1_JAY291 | cds-NP_014444.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:707036-707443:+ | gene-YNR046W_MUCL30387 | rna-NM_001183223.1_MUCL30387 | cds-NP_014444.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:748096-748503:+ | gene-YNR046W_MUCL30388 | rna-NM_001183223.1_MUCL30388 | cds-NP_014444.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:688798-689205:+ | gene-YNR046W_MUCL39482 | rna-NM_001183223.1_MUCL39482 | cds-NP_014444.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:693508-693915:+ | gene-YNR046W_MUCL42920 | rna-NM_001183223.1_MUCL42920 | cds-NP_014444.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:707757-708164:+ | gene-YNR046W_NCIM3186 | rna-NM_001183223.1_NCIM3186 | cds-NP_014444.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:691316-691723:+ | gene-YNR046W_NCYC1407 | rna-NM_001183223.1_NCYC1407 | cds-NP_014444.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:692180-692587:+ | gene-YNR046W_PE2H3 | rna-NM_001183223.1_PE2H3 | cds-NP_014444.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:693582-693989:+ | gene-YNR046W_PE2H4 | rna-NM_001183223.1_PE2H4 | cds-NP_014444.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:707788-708195:+ | gene-YNR046W_S288C | rna-NM_001183223.1_S288C | cds-NP_014444.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000074.1:18122-18529:- | gene-YNR046W_SA1 | rna-NM_001183223.1_SA1 | cds-NP_014444.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:684511-684918:+ | gene-YNR046W_ThermosaccDry | rna-NM_001183223.1_ThermosaccDry | cds-NP_014444.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:726640-727047:+ | gene-YNR046W_VR1 | rna-NM_001183223.1_VR1 | cds-NP_014444.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:594289-594696:+ | gene-YNR046W_ZTW1 | rna-NM_001183223.1_ZTW1 | cds-NP_014444.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:698744-699151:+ | gene-YNR046W_Sparadoxus | rna-NM_001183223.1_Sparadoxus | cds-NP_014444.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |