Gene name: TRM10
Reference locus (S288C): YOL093W
Gene biotype: protein_coding
Description: tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family
Top 10 interactors (score): TRM5 (0.992); TRM82 (0.99); TRM8 (0.99); TRM11 (0.985); TRM7 (0.978); TRM1 (0.976); GCD14 (0.971); NCL1 (0.96); DEG1 (0.952); GCD10 (0.952); DUS4 (0.94); TRM9 (0.929); DUS1 (0.927); PUS1 (0.923); TRM12 (0.922); NOP1 (0.916); TRM3 (0.903); TRM732 (0.887); MOD5 (0.884); ELP2 (0.879)
Homologues (species, bitscore): TRMT10A (Homo sapiens, 148.3); Trmt10a (Mus musculus, 146.0); TRMT10A (Danio rerio, 144.4); trmt10a (Xenopus tropicalis, 145.2); CG14618 (Drosophila melanogaster, 129.0); F25H8.1 (Caenorhabditis elegans, 137.9); AT5G47680 (Arabidopsis thaliana, 134.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:126134-127015:+ | gene-YOL093W_AKU4011 | rna-NM_001183347.1_AKU4011 | cds-NP_014548.1_AKU4011 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:91243-92124:+ | gene-YOL093W_BG1 | rna-NM_001183347.1_BG1 | cds-NP_014548.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:127710-128591:+ | gene-YOL093W_Bruggeman | rna-NM_001183347.1_Bruggeman | cds-NP_014548.1_Bruggeman | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:126591-127472:+ | gene-YOL093W_CAT1 | rna-NM_001183347.1_CAT1 | cds-NP_014548.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:120573-121454:+ | gene-YOL093W_CBS1585 | rna-NM_001183347.1_CBS1585 | cds-NP_014548.1_CBS1585 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:125849-126730:+ | gene-YOL093W_CBS436 | rna-NM_001183347.1_CBS436 | cds-NP_014548.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:120735-121616:+ | gene-YOL093W_CBS6412 | rna-NM_001183347.1_CBS6412 | cds-NP_014548.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:127436-128317:+ | gene-YOL093W_CBS6413 | rna-NM_001183347.1_CBS6413 | cds-NP_014548.1_CBS6413 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:136781-137662:+ | gene-YOL093W_CENPK1137D | rna-NM_001183347.1_CENPK1137D | cds-NP_014548.1_CENPK1137D | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:123734-124615:+ | gene-YOL093W_EthanolRed | rna-NM_001183347.1_EthanolRed | cds-NP_014548.1_EthanolRed | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:126061-126942:+ | gene-YOL093W_FaliES1 | rna-NM_001183347.1_FaliES1 | cds-NP_014548.1_FaliES1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:16527-17408:- | gene-YOL093W_JAY291 | rna-NM_001183347.1_JAY291 | cds-NP_014548.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:131913-132794:+ | gene-YOL093W_MUCL30387 | rna-NM_001183347.1_MUCL30387 | cds-NP_014548.1_MUCL30387 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:135095-135976:+ | gene-YOL093W_MUCL30388 | rna-NM_001183347.1_MUCL30388 | cds-NP_014548.1_MUCL30388 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:128494-129375:+ | gene-YOL093W_MUCL39482 | rna-NM_001183347.1_MUCL39482 | cds-NP_014548.1_MUCL39482 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:144264-145145:+ | gene-YOL093W_MUCL42920 | rna-NM_001183347.1_MUCL42920 | cds-NP_014548.1_MUCL42920 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:142704-143585:+ | gene-YOL093W_NCIM3186 | rna-NM_001183347.1_NCIM3186 | cds-NP_014548.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:135091-135972:+ | gene-YOL093W_NCYC1407 | rna-NM_001183347.1_NCYC1407 | cds-NP_014548.1_NCYC1407 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:118388-119269:+ | gene-YOL093W_PE2H3 | rna-NM_001183347.1_PE2H3 | cds-NP_014548.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:129368-130249:+ | gene-YOL093W_PE2H4 | rna-NM_001183347.1_PE2H4 | cds-NP_014548.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:142815-143696:+ | gene-YOL093W_S288C | rna-NM_001183347.1_S288C | cds-NP_014548.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:110696-111577:+ | gene-YOL093W_SA1 | rna-NM_001183347.1_SA1 | cds-NP_014548.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:125069-125950:+ | gene-YOL093W_ThermosaccDry | rna-NM_001183347.1_ThermosaccDry | cds-NP_014548.1_ThermosaccDry | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:125637-126518:+ | gene-YOL093W_VR1 | rna-NM_001183347.1_VR1 | cds-NP_014548.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:124768-125649:+ | gene-YOL093W_ZTW1 | rna-NM_001183347.1_ZTW1 | cds-NP_014548.1_ZTW1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:128219-129100:+ | gene-YOL093W_Sparadoxus | rna-NM_001183347.1_Sparadoxus | cds-NP_014548.1_Sparadoxus | 91.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |