Gene name: TRM1
Reference locus (S288C): YDR120C
Gene biotype: protein_coding
Description: tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial; tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner nuclear membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB
Top 10 interactors (score): TRM8 (0.999); GCD10 (0.995); NCL1 (0.995); PWP2 (0.994); TRM11 (0.993); SPB1 (0.991); NOP7 (0.99); SDA1 (0.988); MTQ2 (0.986); YTM1 (0.985); NOC2 (0.984); BMS1 (0.984); KRE33 (0.984); NOP14 (0.982); DRS1 (0.981); PWP1 (0.98); TRM2 (0.979); TRM7 (0.978); RRP9 (0.977); TRM10 (0.976)
Homologues (species, bitscore): TRMT1 (Homo sapiens, 348.6); Trmt1 (Mus musculus, 350.1); trmt1 (Danio rerio, 357.1); TRMT1 (Xenopus tropicalis, 341.3); CG6388 (Drosophila melanogaster, 357.5); trm-1 (Caenorhabditis elegans, 307.8); AT3G02320 (Arabidopsis thaliana, 281.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:662493-664205:- | gene-YDR120C_AKU4011 | rna-NM_001180428.3_AKU4011 | cds-NP_010405.3_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:460672-462384:+ | gene-YDR120C_BG1 | rna-NM_001180428.3_BG1 | cds-NP_010405.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:694553-696265:- | gene-YDR120C_Bruggeman | rna-NM_001180428.3_Bruggeman | cds-NP_010405.3_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:681290-683002:- | gene-YDR120C_CAT1 | rna-NM_001180428.3_CAT1 | cds-NP_010405.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:653531-655243:- | gene-YDR120C_CBS1585 | rna-NM_001180428.3_CBS1585 | cds-NP_010405.3_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:679414-681126:- | gene-YDR120C_CBS436 | rna-NM_001180428.3_CBS436 | cds-NP_010405.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:649883-651595:- | gene-YDR120C_CBS6412 | rna-NM_001180428.3_CBS6412 | cds-NP_010405.3_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:678859-680571:- | gene-YDR120C_CBS6413 | rna-NM_001180428.3_CBS6413 | cds-NP_010405.3_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:683999-685711:- | gene-YDR120C_CENPK1137D | rna-NM_001180428.3_CENPK1137D | cds-NP_010405.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:664259-665971:- | gene-YDR120C_EthanolRed | rna-NM_001180428.3_EthanolRed | cds-NP_010405.3_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:671053-672765:- | gene-YDR120C_FaliES1 | rna-NM_001180428.3_FaliES1 | cds-NP_010405.3_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:23171-24883:- | gene-YDR120C_JAY291 | rna-NM_001180428.3_JAY291 | cds-NP_010405.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:680477-682189:- | gene-YDR120C_MUCL30387 | rna-NM_001180428.3_MUCL30387 | cds-NP_010405.3_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:669496-671208:- | gene-YDR120C_MUCL30388 | rna-NM_001180428.3_MUCL30388 | cds-NP_010405.3_MUCL30388 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:654872-656584:- | gene-YDR120C_MUCL39482 | rna-NM_001180428.3_MUCL39482 | cds-NP_010405.3_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:592838-594550:- | gene-YDR120C_MUCL42920 | rna-NM_001180428.3_MUCL42920 | cds-NP_010405.3_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:691472-693184:- | gene-YDR120C_NCIM3186 | rna-NM_001180428.3_NCIM3186 | cds-NP_010405.3_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:654277-655989:- | gene-YDR120C_NCYC1407 | rna-NM_001180428.3_NCYC1407 | cds-NP_010405.3_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:673599-675311:- | gene-YDR120C_PE2H3 | rna-NM_001180428.3_PE2H3 | cds-NP_010405.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:672904-674616:- | gene-YDR120C_PE2H4 | rna-NM_001180428.3_PE2H4 | cds-NP_010405.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:691549-693261:- | gene-YDR120C_S288C | rna-NM_001180428.3_S288C | cds-NP_010405.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:40215-41927:- | gene-YDR120C_SA1 | rna-NM_001180428.3_SA1 | cds-NP_010405.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:670575-672287:- | gene-YDR120C_ThermosaccDry | rna-NM_001180428.3_ThermosaccDry | cds-NP_010405.3_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:683913-685625:- | gene-YDR120C_VR1 | rna-NM_001180428.3_VR1 | cds-NP_010405.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:668161-669873:- | gene-YDR120C_ZTW1 | rna-NM_001180428.3_ZTW1 | cds-NP_010405.3_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:672586-674298:- | gene-YDR120C_Sparadoxus | rna-NM_001180428.3_Sparadoxus | cds-NP_010405.3_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |