TRF5 (YNL299W)


Gene profile

Gene name: TRF5
Reference locus (S288C): YNL299W
Gene biotype: protein_coding

Description: Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Pap2p; Belongs to the DNA polymerase type-B-like family

Top 10 interactors (score): MTR4 (0.999); AIR1 (0.999); AIR2 (0.999); PAP2 (0.989); RRP6 (0.988); PAP1 (0.969); DIS3 (0.953); SKI2 (0.917); DHR2 (0.89); RAT1 (0.861); RRP40 (0.859); MTR3 (0.841); RRP46 (0.834); SKI3 (0.823); CSL4 (0.821); XRN1 (0.818); LRP1 (0.817); RRP45 (0.81); NAB3 (0.808); SKI8 (0.805)

Homologues (species, bitscore): PAPD5 (Homo sapiens, 194.9); Papd5 (Mus musculus, 194.9); papd7 (Danio rerio, 202.6); papd5 (Xenopus tropicalis, 169.1); Trf4-1 (Drosophila melanogaster, 201.8); gld-4 (Caenorhabditis elegans, 166.8); AT5G53770 (Arabidopsis thaliana, 186.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:60329-62257:+ gene-YNL299W_AKU4011 rna-NM_001183137.1_AKU4011 cds-NP_014100.2_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000074.1:28386-30314:- gene-YNL299W_BG1 rna-NM_001183137.1_BG1 cds-NP_014100.2_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:69673-71601:+ gene-YNL299W_Bruggeman rna-NM_001183137.1_Bruggeman cds-NP_014100.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:72281-74209:+ gene-YNL299W_CAT1 rna-NM_001183137.1_CAT1 cds-NP_014100.2_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:60660-62588:+ gene-YNL299W_CBS1585 rna-NM_001183137.1_CBS1585 cds-NP_014100.2_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:61151-63079:+ gene-YNL299W_CBS436 rna-NM_001183137.1_CBS436 cds-NP_014100.2_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:57320-59248:+ gene-YNL299W_CBS6412 rna-NM_001183137.1_CBS6412 cds-NP_014100.2_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:57508-59436:+ gene-YNL299W_CBS6413 rna-NM_001183137.1_CBS6413 cds-NP_014100.2_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:60350-62278:+ gene-YNL299W_CENPK1137D rna-NM_001183137.1_CENPK1137D cds-NP_014100.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:57351-59279:+ gene-YNL299W_EthanolRed rna-NM_001183137.1_EthanolRed cds-NP_014100.2_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:58250-60178:+ gene-YNL299W_FaliES1 rna-NM_001183137.1_FaliES1 cds-NP_014100.2_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000171.1:28040-29968:- gene-YNL299W_JAY291 rna-NM_001183137.1_JAY291 cds-NP_014100.2_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:69923-71851:+ gene-YNL299W_MUCL30387 rna-NM_001183137.1_MUCL30387 cds-NP_014100.2_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:62956-64884:+ gene-YNL299W_MUCL30388 rna-NM_001183137.1_MUCL30388 cds-NP_014100.2_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:58297-60225:+ gene-YNL299W_MUCL39482 rna-NM_001183137.1_MUCL39482 cds-NP_014100.2_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:59987-61915:+ gene-YNL299W_MUCL42920 rna-NM_001183137.1_MUCL42920 cds-NP_014100.2_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:66486-68414:+ gene-YNL299W_NCIM3186 rna-NM_001183137.1_NCIM3186 cds-NP_014100.2_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:59629-61557:+ gene-YNL299W_NCYC1407 rna-NM_001183137.1_NCYC1407 cds-NP_014100.2_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:56828-58756:+ gene-YNL299W_PE2H3 rna-NM_001183137.1_PE2H3 cds-NP_014100.2_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:56216-58144:+ gene-YNL299W_PE2H4 rna-NM_001183137.1_PE2H4 cds-NP_014100.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:66517-68445:+ gene-YNL299W_S288C rna-NM_001183137.1_S288C cds-NP_014100.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000052.1:28772-30700:- gene-YNL299W_SA1 rna-NM_001183137.1_SA1 cds-NP_014100.2_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:59107-61035:+ gene-YNL299W_ThermosaccDry rna-NM_001183137.1_ThermosaccDry cds-NP_014100.2_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:71646-73574:+ gene-YNL299W_VR1 rna-NM_001183137.1_VR1 cds-NP_014100.2_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000029.1:50319-52247:+ gene-YNL299W_ZTW1 rna-NM_001183137.1_ZTW1 cds-NP_014100.2_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:68387-70315:+ gene-YNL299W_Sparadoxus rna-NM_001183137.1_Sparadoxus cds-NP_014100.2_Sparadoxus 88.3 99.7 Verified 1 1 1 False True False False False

Additional files