Gene name: TRE2
Reference locus (S288C): YOR256C
Gene biotype: protein_coding
Description: Putative zinc metalloprotease TRE2; Transferrin receptor-like protein; functions with Tre1p to regulate ubiquitination and vacuolar degradation of the metal transporter Smf1p; inviability of null mutant in systematic studies is due to proximity to CDC31; TRE2 has a paralog, TRE1, that arose from the whole genome duplication; Belongs to the peptidase M28 family. M28B subfamily
Top 10 interactors (score): BUB2 (0.865); CDC16 (0.71); LAA1 (0.71); YIR014W (0.697); SBE2 (0.695); BFA1 (0.692); BSD2 (0.631); PRM10 (0.596); TEM1 (0.595); GYP7 (0.575); SMF2 (0.535); SMX3 (0.526); TRE1 (0.51); LSB6 (0.504); GYL1 (0.497); APL3 (0.496); MOB1 (0.489); APL4 (0.481); LSB1 (0.458); ELA1 (0.42)
Homologues (species, bitscore): NAALAD2 (Homo sapiens, 106.7); Naalad2 (Mus musculus, 93.2); naalad2 (Danio rerio, 85.5); naalad2 (Xenopus tropicalis, 106.7); C35C5.2 (Caenorhabditis elegans, 81.3); AMP1 (Arabidopsis thaliana, 110.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:799029-801458:- | gene-YOR256C_AKU4011 | rna-NM_001183675.2_AKU4011 | cds-NP_014899.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:201062-203491:- | gene-YOR256C_BG1 | rna-NM_001183675.2_BG1 | cds-NP_014899.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:784497-786917:- | gene-YOR256C_Bruggeman | rna-NM_001183675.2_Bruggeman | cds-NP_014899.1_Bruggeman | 98.7 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:785140-787569:- | gene-YOR256C_CAT1 | rna-NM_001183675.2_CAT1 | cds-NP_014899.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:782018-784447:- | gene-YOR256C_CBS1585 | rna-NM_001183675.2_CBS1585 | cds-NP_014899.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:780706-783135:- | gene-YOR256C_CBS436 | rna-NM_001183675.2_CBS436 | cds-NP_014899.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:779137-781566:- | gene-YOR256C_CBS6412 | rna-NM_001183675.2_CBS6412 | cds-NP_014899.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:787778-790207:- | gene-YOR256C_CBS6413 | rna-NM_001183675.2_CBS6413 | cds-NP_014899.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:808015-810444:- | gene-YOR256C_CENPK1137D | rna-NM_001183675.2_CENPK1137D | cds-NP_014899.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:775145-777574:- | gene-YOR256C_EthanolRed | rna-NM_001183675.2_EthanolRed | cds-NP_014899.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:780544-782973:- | gene-YOR256C_FaliES1 | rna-NM_001183675.2_FaliES1 | cds-NP_014899.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:43861-46290:+ | gene-YOR256C_JAY291 | rna-NM_001183675.2_JAY291 | cds-NP_014899.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:788770-791199:- | gene-YOR256C_MUCL30387 | rna-NM_001183675.2_MUCL30387 | cds-NP_014899.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:795886-798315:- | gene-YOR256C_MUCL30388 | rna-NM_001183675.2_MUCL30388 | cds-NP_014899.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:789349-791778:- | gene-YOR256C_MUCL39482 | rna-NM_001183675.2_MUCL39482 | cds-NP_014899.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:798933-801362:- | gene-YOR256C_MUCL42920 | rna-NM_001183675.2_MUCL42920 | cds-NP_014899.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:808143-810572:- | gene-YOR256C_NCIM3186 | rna-NM_001183675.2_NCIM3186 | cds-NP_014899.1_NCIM3186 | 94.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:789447-791876:- | gene-YOR256C_NCYC1407 | rna-NM_001183675.2_NCYC1407 | cds-NP_014899.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:788744-791173:- | gene-YOR256C_PE2H3 | rna-NM_001183675.2_PE2H3 | cds-NP_014899.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:799121-801550:- | gene-YOR256C_PE2H4 | rna-NM_001183675.2_PE2H4 | cds-NP_014899.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:808254-810683:- | gene-YOR256C_S288C | rna-NM_001183675.2_S288C | cds-NP_014899.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:218244-220673:- | gene-YOR256C_SA1 | rna-NM_001183675.2_SA1 | cds-NP_014899.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:779727-782156:- | gene-YOR256C_ThermosaccDry | rna-NM_001183675.2_ThermosaccDry | cds-NP_014899.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:843184-845613:- | gene-YOR256C_VR1 | rna-NM_001183675.2_VR1 | cds-NP_014899.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:512646-515075:- | gene-YOR256C_ZTW1 | rna-NM_001183675.2_ZTW1 | cds-NP_014899.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:785507-787939:- | gene-YOR256C_Sparadoxus | rna-NM_001183675.2_Sparadoxus | cds-NP_014899.1_Sparadoxus | 88.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |