TPS1 (YBR126C)


Gene profile

Gene name: TPS1
Reference locus (S288C): YBR126C
Gene biotype: protein_coding

Description: Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit; Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose, which is critically important for survival of long-term desiccation; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress and in response to prolonged exposure to boric acid

Top 10 interactors (score): TSL1 (0.999); TPS2 (0.999); TPS3 (0.999); NTH1 (0.998); HSP104 (0.994); NTH2 (0.993); UGP1 (0.992); GSY2 (0.99); GLC3 (0.981); GSY1 (0.981); PGM2 (0.979); YBR056W (0.976); YDL124W (0.962); HSP78 (0.959); GPD1 (0.957); GLK1 (0.948); HXK1 (0.94); YHL012W (0.932); HSP26 (0.928); MSC1 (0.923)

Homologues (species, bitscore): Tps1 (Drosophila melanogaster, 328.9); tps-2 (Caenorhabditis elegans, 168.3); TPS1 (Arabidopsis thaliana, 475.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:471799-473286:- gene-YBR126C_AKU4011 rna-NM_001178474.1_AKU4011 cds-NP_009684.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:462344-463831:- gene-YBR126C_BG1 rna-NM_001178474.1_BG1 cds-NP_009684.1_BG1 99.3 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:473576-475063:- gene-YBR126C_Bruggeman rna-NM_001178474.1_Bruggeman cds-NP_009684.1_Bruggeman 99.4 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:476747-478234:- gene-YBR126C_CAT1 rna-NM_001178474.1_CAT1 cds-NP_009684.1_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:463583-465070:- gene-YBR126C_CBS1585 rna-NM_001178474.1_CBS1585 cds-NP_009684.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:471659-473146:- gene-YBR126C_CBS436 rna-NM_001178474.1_CBS436 cds-NP_009684.1_CBS436 99.3 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:561446-562933:- gene-YBR126C_CBS6412 rna-NM_001178474.1_CBS6412 cds-NP_009684.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:469211-470698:- gene-YBR126C_CBS6413 rna-NM_001178474.1_CBS6413 cds-NP_009684.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:482675-484162:- gene-YBR126C_CENPK1137D rna-NM_001178474.1_CENPK1137D cds-NP_009684.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:597819-599306:- gene-YBR126C_EthanolRed rna-NM_001178474.1_EthanolRed cds-NP_009684.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:487836-489323:- gene-YBR126C_FaliES1 rna-NM_001178474.1_FaliES1 cds-NP_009684.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000444.1:11250-12737:- gene-YBR126C_JAY291 rna-NM_001178474.1_JAY291 cds-NP_009684.1_JAY291 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:476481-477968:- gene-YBR126C_MUCL30387 rna-NM_001178474.1_MUCL30387 cds-NP_009684.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:474840-476327:- gene-YBR126C_MUCL30388 rna-NM_001178474.1_MUCL30388 cds-NP_009684.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:461976-463463:- gene-YBR126C_MUCL39482 rna-NM_001178474.1_MUCL39482 cds-NP_009684.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:471895-473382:- gene-YBR126C_MUCL42920 rna-NM_001178474.1_MUCL42920 cds-NP_009684.1_MUCL42920 99.3 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:488702-490189:- gene-YBR126C_NCIM3186 rna-NM_001178474.1_NCIM3186 cds-NP_009684.1_NCIM3186 99.4 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:464504-465991:- gene-YBR126C_NCYC1407 rna-NM_001178474.1_NCYC1407 cds-NP_009684.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:477089-478576:- gene-YBR126C_PE2H3 rna-NM_001178474.1_PE2H3 cds-NP_009684.1_PE2H3 99.4 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:474765-476252:- gene-YBR126C_PE2H4 rna-NM_001178474.1_PE2H4 cds-NP_009684.1_PE2H4 99.4 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:488905-490392:- gene-YBR126C_S288C rna-NM_001178474.1_S288C cds-NP_009684.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000032.1:10021-11508:- gene-YBR126C_SA1 rna-NM_001178474.1_SA1 cds-NP_009684.1_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:486843-488330:- gene-YBR126C_ThermosaccDry rna-NM_001178474.1_ThermosaccDry cds-NP_009684.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:468342-469829:- gene-YBR126C_VR1 rna-NM_001178474.1_VR1 cds-NP_009684.1_VR1 99.4 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:461993-463480:- gene-YBR126C_ZTW1 rna-NM_001178474.1_ZTW1 cds-NP_009684.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:499212-500699:- gene-YBR126C_Sparadoxus rna-NM_001178474.1_Sparadoxus cds-NP_009684.1_Sparadoxus 92.4 100.0 Verified 1 1 1 False True False False False

Additional files