TPO3 (YPR156C)


Gene profile

Gene name: TPO3
Reference locus (S288C): YPR156C
Gene biotype: protein_coding

Description: Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; specific for spermine; localizes to the plasma membrane; TPO3 has a paralog, TPO2, that arose from the whole genome duplication; Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily

Top 10 interactors (score): TPO2 (0.999); HAA1 (0.942); QDR2 (0.914); TDA6 (0.904); HRK1 (0.752); PDR12 (0.75); YRO2 (0.715); YGP1 (0.712); YDR239C (0.698); AZR1 (0.696); FPS1 (0.694); STP4 (0.677); PDR16 (0.673); YLR297W (0.663); SNQ2 (0.643); MSN4 (0.617); SAP30 (0.616); COM2 (0.581); PDR1 (0.572); SPI1 (0.571)

Homologues (species, bitscore): TMT3 (Arabidopsis thaliana, 50.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:804060-805927:- gene-YPR156C_AKU4011 rna-NM_001184253.1_AKU4011 cds-NP_015482.1_AKU4011 56.3 99.9 Unannotated 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:91450-93318:+ gene-YPR156C_BG1 rna-NM_001184253.1_BG1 cds-NP_015482.1_BG1 99.0 100.0 Mismatch 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:884602-886463:- gene-YPR156C_Bruggeman rna-NM_001184253.1_Bruggeman cds-NP_015482.1_Bruggeman 93.7 97.5 Mismatch 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:926623-928490:- gene-YPR156C_CAT1 rna-NM_001184253.1_CAT1 cds-NP_015482.1_CAT1 69.7 99.9 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:808298-810165:- gene-YPR156C_CBS1585 rna-NM_001184253.1_CBS1585 cds-NP_015482.1_CBS1585 67.7 99.9 Unannotated 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:822407-824274:- gene-YPR156C_CBS436 rna-NM_001184253.1_CBS436 cds-NP_015482.1_CBS436 71.2 99.9 Unannotated 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:811047-812567:- gene-YPR156C_CBS6412 rna-NM_001184253.1_CBS6412 cds-NP_015482.1_CBS6412 79.9 81.3 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:805760-807627:- gene-YPR156C_CBS6413 rna-NM_001184253.1_CBS6413 cds-NP_015482.1_CBS6413 56.3 99.9 Unannotated 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:837902-839790:- gene-YPR156C_CENPK1137D rna-NM_001184253.1_CENPK1137D cds-NP_015482.1_CENPK1137D 69.6 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1126195-1127887:- gene-YPR156C_EthanolRed rna-NM_001184253.1_EthanolRed cds-NP_015482.1_EthanolRed 89.0 90.5 Unannotated 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:805742-807610:- gene-YPR156C_FaliES1 rna-NM_001184253.1_FaliES1 cds-NP_015482.1_FaliES1 98.3 100.0 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000251.1:3-700:- gene-YPR156C_JAY291 rna-NM_001184253.1_JAY291 cds-NP_015482.1_JAY291 37.0 37.3 Mismatch 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:852680-854551:- gene-YPR156C_MUCL30387 rna-NM_001184253.1_MUCL30387 cds-NP_015482.1_MUCL30387 98.4 100.0 Mismatch 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:825264-827131:- gene-YPR156C_MUCL30388 rna-NM_001184253.1_MUCL30388 cds-NP_015482.1_MUCL30388 72.1 99.9 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:801066-802927:- gene-YPR156C_MUCL39482 rna-NM_001184253.1_MUCL39482 cds-NP_015482.1_MUCL39482 96.3 99.1 Mismatch 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:865068-866935:- gene-YPR156C_MUCL42920 rna-NM_001184253.1_MUCL42920 cds-NP_015482.1_MUCL42920 61.6 99.9 Unannotated 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:837892-839760:- gene-YPR156C_NCIM3186 rna-NM_001184253.1_NCIM3186 cds-NP_015482.1_NCIM3186 98.3 100.0 Mismatch 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:809410-811277:- gene-YPR156C_NCYC1407 rna-NM_001184253.1_NCYC1407 cds-NP_015482.1_NCYC1407 56.3 99.9 Unannotated 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:816126-817994:- gene-YPR156C_PE2H3 rna-NM_001184253.1_PE2H3 cds-NP_015482.1_PE2H3 99.0 100.0 Mismatch 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:815774-817642:- gene-YPR156C_PE2H4 rna-NM_001184253.1_PE2H4 cds-NP_015482.1_PE2H4 99.0 100.0 Mismatch 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:837909-839777:- gene-YPR156C_S288C rna-NM_001184253.1_S288C cds-NP_015482.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000060.1:74175-74927:+ gene-YPR156C_SA1 rna-NM_001184253.1_SA1 cds-NP_015482.1_SA1 40.2 40.2 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:805184-807301:- gene-YPR156C_ThermosaccDry rna-NM_001184253.1_ThermosaccDry cds-NP_015482.1_ThermosaccDry 86.8 100.0 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:827626-829493:- gene-YPR156C_VR1 rna-NM_001184253.1_VR1 cds-NP_015482.1_VR1 73.9 99.9 Unannotated 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:808558-810426:- gene-YPR156C_ZTW1 rna-NM_001184253.1_ZTW1 cds-NP_015482.1_ZTW1 98.5 100.0 Mismatch 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:810527-812395:- gene-YPR156C_Sparadoxus rna-NM_001184253.1_Sparadoxus cds-NP_015482.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files