Gene name: TPO2
Reference locus (S288C): YGR138C
Gene biotype: protein_coding
Description: Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; TPO2 has a paralog, TPO3, that arose from the whole genome duplication
Top 10 interactors (score): TPO3 (0.999); HAA1 (0.953); QDR2 (0.914); PDR12 (0.852); TDA6 (0.832); AZR1 (0.813); YRO2 (0.8); HRK1 (0.774); HSP30 (0.768); PDR18 (0.749); YGP1 (0.745); SNQ2 (0.72); FPS1 (0.712); PDR5 (0.703); COM2 (0.695); WAR1 (0.671); STP4 (0.657); YLR297W (0.636); PMA1 (0.623); DUR3 (0.578)
Homologues (species, bitscore): ZIF1 (Arabidopsis thaliana, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:743044-745086:- | gene-YGR138C_AKU4011 | rna-NM_001181267.1_AKU4011 | cds-NP_011654.1_AKU4011 | 84.7 | 97.2 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:21512-23356:- | gene-YGR138C_BG1 | rna-NM_001181267.1_BG1 | cds-NP_011654.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:745540-747383:- | gene-YGR138C_Bruggeman | rna-NM_001181267.1_Bruggeman | cds-NP_011654.1_Bruggeman | 71.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:744284-746626:- | gene-YGR138C_CAT1 | rna-NM_001181267.1_CAT1 | cds-NP_011654.1_CAT1 | 78.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:743998-745820:- | gene-YGR138C_CBS1585 | rna-NM_001181267.1_CBS1585 | cds-NP_011654.1_CBS1585 | 97.2 | 98.8 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:747114-749207:- | gene-YGR138C_CBS436 | rna-NM_001181267.1_CBS436 | cds-NP_011654.1_CBS436 | 88.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:735402-736841:- | gene-YGR138C_CBS6412 | rna-NM_001181267.1_CBS6412 | cds-NP_011654.1_CBS6412 | 68.2 | 78.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:740636-742678:- | gene-YGR138C_CBS6413 | rna-NM_001181267.1_CBS6413 | cds-NP_011654.1_CBS6413 | 84.6 | 97.2 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:763474-765340:- | gene-YGR138C_CENPK1137D | rna-NM_001181267.1_CENPK1137D | cds-NP_011654.1_CENPK1137D | 82.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:729768-731384:- | gene-YGR138C_EthanolRed | rna-NM_001181267.1_EthanolRed | cds-NP_011654.1_EthanolRed | 75.3 | 87.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:733629-735472:- | gene-YGR138C_FaliES1 | rna-NM_001181267.1_FaliES1 | cds-NP_011654.1_FaliES1 | 67.2 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000438.1:1-1625:- | gene-YGR138C_JAY291 | rna-NM_001181267.1_JAY291 | cds-NP_011654.1_JAY291 | 88.0 | 88.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:745701-746617:- | gene-YGR138C_MUCL30387 | rna-NM_001181267.1_MUCL30387 | cds-NP_011654.1_MUCL30387 | 49.3 | 49.7 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:745552-747645:- | gene-YGR138C_MUCL30388 | rna-NM_001181267.1_MUCL30388 | cds-NP_011654.1_MUCL30388 | 87.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:739453-741296:- | gene-YGR138C_MUCL39482 | rna-NM_001181267.1_MUCL39482 | cds-NP_011654.1_MUCL39482 | 63.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:749548-751392:- | gene-YGR138C_MUCL42920 | rna-NM_001181267.1_MUCL42920 | cds-NP_011654.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:763762-765606:- | gene-YGR138C_NCIM3186 | rna-NM_001181267.1_NCIM3186 | cds-NP_011654.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:734454-736496:- | gene-YGR138C_NCYC1407 | rna-NM_001181267.1_NCYC1407 | cds-NP_011654.1_NCYC1407 | 84.6 | 97.2 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:754003-755847:- | gene-YGR138C_PE2H3 | rna-NM_001181267.1_PE2H3 | cds-NP_011654.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:759113-760957:- | gene-YGR138C_PE2H4 | rna-NM_001181267.1_PE2H4 | cds-NP_011654.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:763762-765606:- | gene-YGR138C_S288C | rna-NM_001181267.1_S288C | cds-NP_011654.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000221.1:1-1047:- | gene-YGR138C_SA1 | rna-NM_001181267.1_SA1 | cds-NP_011654.1_SA1 | 56.5 | 56.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:754252-756095:- | gene-YGR138C_ThermosaccDry | rna-NM_001181267.1_ThermosaccDry | cds-NP_011654.1_ThermosaccDry | 71.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:857750-860092:- | gene-YGR138C_VR1 | rna-NM_001181267.1_VR1 | cds-NP_011654.1_VR1 | 78.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:56398-58242:- | gene-YGR138C_ZTW1 | rna-NM_001181267.1_ZTW1 | cds-NP_011654.1_ZTW1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:744113-745957:- | gene-YGR138C_Sparadoxus | rna-NM_001181267.1_Sparadoxus | cds-NP_011654.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |