Gene name: TPK2
Reference locus (S288C): YPL203W
Gene biotype: protein_coding
Description: cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): BCY1 (0.999); TPK1 (0.998); CYR1 (0.998); RAS2 (0.997); RAS1 (0.994); PDE2 (0.985); MSN4 (0.984); MSN2 (0.982); TPK3 (0.979); GPA2 (0.965); NTH1 (0.953); SOK2 (0.94); IRA2 (0.922); SLT2 (0.9); YAK1 (0.899); SFL1 (0.898); YLR345W (0.897); GPR1 (0.887); RIM15 (0.885); PDE1 (0.883)
Homologues (species, bitscore): PRKACA (Homo sapiens, 358.2); Prkacb (Mus musculus, 361.3); prkacab (Danio rerio, 363.2); prkaca (Xenopus tropicalis, 360.1); Pka-C1 (Drosophila melanogaster, 352.4); kin-1 (Caenorhabditis elegans, 337.4); S6K2 (Arabidopsis thaliana, 238.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:144132-145274:+ | gene-YPL203W_AKU4011 | rna-NM_001184017.1_AKU4011 | cds-NP_015121.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:349895-351037:+ | gene-YPL203W_BG1 | rna-NM_001184017.1_BG1 | cds-NP_015121.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:169593-170735:+ | gene-YPL203W_Bruggeman | rna-NM_001184017.1_Bruggeman | cds-NP_015121.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:166197-167339:+ | gene-YPL203W_CAT1 | rna-NM_001184017.1_CAT1 | cds-NP_015121.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:148318-149460:+ | gene-YPL203W_CBS1585 | rna-NM_001184017.1_CBS1585 | cds-NP_015121.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:162737-163879:+ | gene-YPL203W_CBS436 | rna-NM_001184017.1_CBS436 | cds-NP_015121.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:153121-154263:+ | gene-YPL203W_CBS6412 | rna-NM_001184017.1_CBS6412 | cds-NP_015121.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:144495-145637:+ | gene-YPL203W_CBS6413 | rna-NM_001184017.1_CBS6413 | cds-NP_015121.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:166203-167345:+ | gene-YPL203W_CENPK1137D | rna-NM_001184017.1_CENPK1137D | cds-NP_015121.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:143250-144392:+ | gene-YPL203W_EthanolRed | rna-NM_001184017.1_EthanolRed | cds-NP_015121.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:150456-151598:+ | gene-YPL203W_FaliES1 | rna-NM_001184017.1_FaliES1 | cds-NP_015121.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:6731-7873:- | gene-YPL203W_JAY291 | rna-NM_001184017.1_JAY291 | cds-NP_015121.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:161305-162447:+ | gene-YPL203W_MUCL30387 | rna-NM_001184017.1_MUCL30387 | cds-NP_015121.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:159498-160640:+ | gene-YPL203W_MUCL30388 | rna-NM_001184017.1_MUCL30388 | cds-NP_015121.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:141448-142590:+ | gene-YPL203W_MUCL39482 | rna-NM_001184017.1_MUCL39482 | cds-NP_015121.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:160327-161469:+ | gene-YPL203W_MUCL42920 | rna-NM_001184017.1_MUCL42920 | cds-NP_015121.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:166239-167381:+ | gene-YPL203W_NCIM3186 | rna-NM_001184017.1_NCIM3186 | cds-NP_015121.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:147897-149039:+ | gene-YPL203W_NCYC1407 | rna-NM_001184017.1_NCYC1407 | cds-NP_015121.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:155607-156749:+ | gene-YPL203W_PE2H3 | rna-NM_001184017.1_PE2H3 | cds-NP_015121.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:155250-156392:+ | gene-YPL203W_PE2H4 | rna-NM_001184017.1_PE2H4 | cds-NP_015121.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:166256-167398:+ | gene-YPL203W_S288C | rna-NM_001184017.1_S288C | cds-NP_015121.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:6787-7929:- | gene-YPL203W_SA1 | rna-NM_001184017.1_SA1 | cds-NP_015121.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:150237-151379:+ | gene-YPL203W_ThermosaccDry | rna-NM_001184017.1_ThermosaccDry | cds-NP_015121.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:165145-166287:+ | gene-YPL203W_VR1 | rna-NM_001184017.1_VR1 | cds-NP_015121.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:149757-150899:+ | gene-YPL203W_ZTW1 | rna-NM_001184017.1_ZTW1 | cds-NP_015121.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:151305-152447:+ | gene-YPL203W_Sparadoxus | rna-NM_001184017.1_Sparadoxus | cds-NP_015121.1_Sparadoxus | 92.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |