Gene name: TOS4
Reference locus (S288C): YLR183C
Gene biotype: protein_coding
Description: Protein TOS4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress
Top 10 interactors (score): HOS2 (0.941); UME6 (0.936); RPD3 (0.934); SET3 (0.93); ASH1 (0.926); DUT1 (0.923); RXT3 (0.906); CTI6 (0.903); UME1 (0.903); SNT1 (0.903); TOD6 (0.9); SDS3 (0.9); RXT2 (0.9); SIF2 (0.9); DEP1 (0.9); SAP30 (0.9); PHO23 (0.9); DOT6 (0.9); SIN3 (0.9); CDC6 (0.892)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:474667-476136:- | gene-YLR183C_AKU4011 | rna-NM_001182070.1_AKU4011 | cds-NP_013284.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:31865-33334:- | gene-YLR183C_BG1 | rna-NM_001182070.1_BG1 | cds-NP_013284.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:514916-516385:- | gene-YLR183C_Bruggeman | rna-NM_001182070.1_Bruggeman | cds-NP_013284.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:514511-515980:- | gene-YLR183C_CAT1 | rna-NM_001182070.1_CAT1 | cds-NP_013284.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:510162-511631:- | gene-YLR183C_CBS1585 | rna-NM_001182070.1_CBS1585 | cds-NP_013284.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:500300-501769:- | gene-YLR183C_CBS436 | rna-NM_001182070.1_CBS436 | cds-NP_013284.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:478719-480188:- | gene-YLR183C_CBS6412 | rna-NM_001182070.1_CBS6412 | cds-NP_013284.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:510454-511923:- | gene-YLR183C_CBS6413 | rna-NM_001182070.1_CBS6413 | cds-NP_013284.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:505195-506664:- | gene-YLR183C_CENPK1137D | rna-NM_001182070.1_CENPK1137D | cds-NP_013284.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:474191-475660:- | gene-YLR183C_EthanolRed | rna-NM_001182070.1_EthanolRed | cds-NP_013284.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:503118-504587:- | gene-YLR183C_FaliES1 | rna-NM_001182070.1_FaliES1 | cds-NP_013284.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:30021-31490:- | gene-YLR183C_JAY291 | rna-NM_001182070.1_JAY291 | cds-NP_013284.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:514937-516406:- | gene-YLR183C_MUCL30387 | rna-NM_001182070.1_MUCL30387 | cds-NP_013284.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:519869-521338:- | gene-YLR183C_MUCL30388 | rna-NM_001182070.1_MUCL30388 | cds-NP_013284.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:511143-512612:- | gene-YLR183C_MUCL39482 | rna-NM_001182070.1_MUCL39482 | cds-NP_013284.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:511641-513110:- | gene-YLR183C_MUCL42920 | rna-NM_001182070.1_MUCL42920 | cds-NP_013284.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:520517-521986:- | gene-YLR183C_NCIM3186 | rna-NM_001182070.1_NCIM3186 | cds-NP_013284.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:503570-505039:- | gene-YLR183C_NCYC1407 | rna-NM_001182070.1_NCYC1407 | cds-NP_013284.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:507809-509278:- | gene-YLR183C_PE2H3 | rna-NM_001182070.1_PE2H3 | cds-NP_013284.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:507553-509022:- | gene-YLR183C_PE2H4 | rna-NM_001182070.1_PE2H4 | cds-NP_013284.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:520543-522012:- | gene-YLR183C_S288C | rna-NM_001182070.1_S288C | cds-NP_013284.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:30078-31547:- | gene-YLR183C_SA1 | rna-NM_001182070.1_SA1 | cds-NP_013284.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:505621-507090:- | gene-YLR183C_ThermosaccDry | rna-NM_001182070.1_ThermosaccDry | cds-NP_013284.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:516922-518391:- | gene-YLR183C_VR1 | rna-NM_001182070.1_VR1 | cds-NP_013284.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:29914-31383:- | gene-YLR183C_ZTW1 | rna-NM_001182070.1_ZTW1 | cds-NP_013284.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:491737-493215:- | gene-YLR183C_Sparadoxus | rna-NM_001182070.1_Sparadoxus | cds-NP_013284.1_Sparadoxus | 85.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |