Gene name: TOS2
Reference locus (S288C): YGR221C
Gene biotype: protein_coding
Description: Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p; TOS2 has a paralog, SKG6, that arose from the whole genome duplication; Belongs to the SKG6/TOS2 family
Top 10 interactors (score): CDC24 (0.812); TOS1 (0.779); GIC1 (0.762); YDL071C (0.749); SSP2 (0.747); HUA1 (0.715); HUA2 (0.676); TOS3 (0.651); GIC2 (0.627); PKC1 (0.59); AIM10 (0.569); RGD1 (0.561); VHS2 (0.529); SPO74 (0.525); ALK2 (0.523); MLF3 (0.52); RHO4 (0.517); MSB1 (0.497); RHO3 (0.488); COS10 (0.482)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:902428-904296:- | gene-YGR221C_AKU4011 | rna-NM_001181350.2_AKU4011 | cds-NP_011737.2_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:182650-184518:- | gene-YGR221C_BG1 | rna-NM_001181350.2_BG1 | cds-NP_011737.2_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:910132-912000:- | gene-YGR221C_Bruggeman | rna-NM_001181350.2_Bruggeman | cds-NP_011737.2_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:908382-910250:- | gene-YGR221C_CAT1 | rna-NM_001181350.2_CAT1 | cds-NP_011737.2_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:905378-907246:- | gene-YGR221C_CBS1585 | rna-NM_001181350.2_CBS1585 | cds-NP_011737.2_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:909058-910926:- | gene-YGR221C_CBS436 | rna-NM_001181350.2_CBS436 | cds-NP_011737.2_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:896248-898116:- | gene-YGR221C_CBS6412 | rna-NM_001181350.2_CBS6412 | cds-NP_011737.2_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:902307-904175:- | gene-YGR221C_CBS6413 | rna-NM_001181350.2_CBS6413 | cds-NP_011737.2_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:936706-938574:- | gene-YGR221C_CENPK1137D | rna-NM_001181350.2_CENPK1137D | cds-NP_011737.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:890758-892626:- | gene-YGR221C_EthanolRed | rna-NM_001181350.2_EthanolRed | cds-NP_011737.2_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:895149-897017:- | gene-YGR221C_FaliES1 | rna-NM_001181350.2_FaliES1 | cds-NP_011737.2_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:133248-135116:+ | gene-YGR221C_JAY291 | rna-NM_001181350.2_JAY291 | cds-NP_011737.2_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:908047-909915:- | gene-YGR221C_MUCL30387 | rna-NM_001181350.2_MUCL30387 | cds-NP_011737.2_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:907303-909171:- | gene-YGR221C_MUCL30388 | rna-NM_001181350.2_MUCL30388 | cds-NP_011737.2_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:900455-902323:- | gene-YGR221C_MUCL39482 | rna-NM_001181350.2_MUCL39482 | cds-NP_011737.2_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:919007-920875:- | gene-YGR221C_MUCL42920 | rna-NM_001181350.2_MUCL42920 | cds-NP_011737.2_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:937124-938992:- | gene-YGR221C_NCIM3186 | rna-NM_001181350.2_NCIM3186 | cds-NP_011737.2_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:896107-897975:- | gene-YGR221C_NCYC1407 | rna-NM_001181350.2_NCYC1407 | cds-NP_011737.2_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:921045-922913:- | gene-YGR221C_PE2H3 | rna-NM_001181350.2_PE2H3 | cds-NP_011737.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:926155-928023:- | gene-YGR221C_PE2H4 | rna-NM_001181350.2_PE2H4 | cds-NP_011737.2_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:937124-938992:- | gene-YGR221C_S288C | rna-NM_001181350.2_S288C | cds-NP_011737.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:62772-64640:+ | gene-YGR221C_SA1 | rna-NM_001181350.2_SA1 | cds-NP_011737.2_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:915660-917528:- | gene-YGR221C_ThermosaccDry | rna-NM_001181350.2_ThermosaccDry | cds-NP_011737.2_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1020473-1022341:- | gene-YGR221C_VR1 | rna-NM_001181350.2_VR1 | cds-NP_011737.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:217095-218963:- | gene-YGR221C_ZTW1 | rna-NM_001181350.2_ZTW1 | cds-NP_011737.2_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:907738-909658:- | gene-YGR221C_Sparadoxus | rna-NM_001181350.2_Sparadoxus | cds-NP_011737.2_Sparadoxus | 82.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |