TOM70 (YNL121C)


Gene profile

Gene name: TOM70
Reference locus (S288C): YNL121C
Gene biotype: protein_coding

Description: Mitochondrial import receptor subunit TOM70; Component of the TOM (translocase of outer membrane) complex; involved in the recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins; TOM70 has a paralog, TOM71, that arose from the whole genome duplication

Top 10 interactors (score): TOM22 (0.999); TOM20 (0.999); TOM40 (0.999); TOM7 (0.998); SAM50 (0.997); SAM37 (0.997); TOM5 (0.986); TIM54 (0.985); SAM35 (0.983); HSP82 (0.982); TIM22 (0.98); MDM10 (0.98); TOM6 (0.977); MMM1 (0.969); TIM50 (0.964); GEM1 (0.962); TIM17 (0.961); ATP2 (0.958); CYT1 (0.957); HSP60 (0.957)

Homologues (species, bitscore): TOMM70A (Homo sapiens, 138.7); Tomm70a (Mus musculus, 128.6); tomm70a (Danio rerio, 140.2); tomm70a (Xenopus tropicalis, 132.5); Tom70 (Drosophila melanogaster, 104.8); pph-5 (Caenorhabditis elegans, 61.2); AT4G30480 (Arabidopsis thaliana, 76.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:392367-394220:- gene-YNL121C_AKU4011 rna-NM_001182959.3_AKU4011 cds-NP_014278.3_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:296364-298217:- gene-YNL121C_BG1 rna-NM_001182959.3_BG1 cds-NP_014278.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:402833-404686:- gene-YNL121C_Bruggeman rna-NM_001182959.3_Bruggeman cds-NP_014278.3_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:446134-447987:- gene-YNL121C_CAT1 rna-NM_001182959.3_CAT1 cds-NP_014278.3_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:392987-394840:- gene-YNL121C_CBS1585 rna-NM_001182959.3_CBS1585 cds-NP_014278.3_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:461399-463252:- gene-YNL121C_CBS436 rna-NM_001182959.3_CBS436 cds-NP_014278.3_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:388440-390293:- gene-YNL121C_CBS6412 rna-NM_001182959.3_CBS6412 cds-NP_014278.3_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:389405-391258:- gene-YNL121C_CBS6413 rna-NM_001182959.3_CBS6413 cds-NP_014278.3_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:392534-394387:- gene-YNL121C_CENPK1137D rna-NM_001182959.3_CENPK1137D cds-NP_014278.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:389357-391210:- gene-YNL121C_EthanolRed rna-NM_001182959.3_EthanolRed cds-NP_014278.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:385259-387112:- gene-YNL121C_FaliES1 rna-NM_001182959.3_FaliES1 cds-NP_014278.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000021.1:41641-43494:- gene-YNL121C_JAY291 rna-NM_001182959.3_JAY291 cds-NP_014278.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:399252-401105:- gene-YNL121C_MUCL30387 rna-NM_001182959.3_MUCL30387 cds-NP_014278.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:434431-436284:- gene-YNL121C_MUCL30388 rna-NM_001182959.3_MUCL30388 cds-NP_014278.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:390266-392119:- gene-YNL121C_MUCL39482 rna-NM_001182959.3_MUCL39482 cds-NP_014278.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:393506-395359:- gene-YNL121C_MUCL42920 rna-NM_001182959.3_MUCL42920 cds-NP_014278.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:398653-400506:- gene-YNL121C_NCIM3186 rna-NM_001182959.3_NCIM3186 cds-NP_014278.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:392398-394251:- gene-YNL121C_NCYC1407 rna-NM_001182959.3_NCYC1407 cds-NP_014278.3_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:391390-393243:- gene-YNL121C_PE2H3 rna-NM_001182959.3_PE2H3 cds-NP_014278.3_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:390796-392649:- gene-YNL121C_PE2H4 rna-NM_001182959.3_PE2H4 cds-NP_014278.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:398684-400537:- gene-YNL121C_S288C rna-NM_001182959.3_S288C cds-NP_014278.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:12987-14840:+ gene-YNL121C_SA1 rna-NM_001182959.3_SA1 cds-NP_014278.3_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:386113-387966:- gene-YNL121C_ThermosaccDry rna-NM_001182959.3_ThermosaccDry cds-NP_014278.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:404779-406632:- gene-YNL121C_VR1 rna-NM_001182959.3_VR1 cds-NP_014278.3_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:295946-297799:- gene-YNL121C_ZTW1 rna-NM_001182959.3_ZTW1 cds-NP_014278.3_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:396931-398784:- gene-YNL121C_Sparadoxus rna-NM_001182959.3_Sparadoxus cds-NP_014278.3_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files