TOM40 (YMR203W)


Gene profile

Gene name: TOM40
Reference locus (S288C): YMR203W
Gene biotype: protein_coding

Description: Mitochondrial import receptor subunit TOM40; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore; pre-Tom40p is phosphorylated by PKA, which impairs its import into mitochondria under non-respiratory conditions

Top 10 interactors (score): SAM37 (0.999); TOM7 (0.999); SAM50 (0.999); TOM5 (0.999); TOM20 (0.999); MDM10 (0.999); TOM70 (0.999); TIM50 (0.999); TOM22 (0.999); TIM17 (0.999); POR1 (0.999); SAM35 (0.998); TIM13 (0.997); TIM8 (0.996); TOM6 (0.995); TIM44 (0.995); TIM23 (0.994); TIM10 (0.992); TIM22 (0.991); HSP60 (0.991)

Homologues (species, bitscore): TOMM40L (Homo sapiens, 82.8); Tomm40l (Mus musculus, 87.4); tomm40l (Danio rerio, 85.9); TOMM40L (Xenopus tropicalis, 76.3); Tom40 (Drosophila melanogaster, 105.9); tomm-40 (Caenorhabditis elegans, 60.1); AT1G50400 (Arabidopsis thaliana, 98.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:708420-709583:+ gene-YMR203W_AKU4011 rna-NM_001182710.1_AKU4011 cds-NP_013930.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:244964-246127:- gene-YMR203W_BG1 rna-NM_001182710.1_BG1 cds-NP_013930.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:652631-653794:+ gene-YMR203W_Bruggeman rna-NM_001182710.1_Bruggeman cds-NP_013930.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:655885-657048:+ gene-YMR203W_CAT1 rna-NM_001182710.1_CAT1 cds-NP_013930.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:640677-641840:+ gene-YMR203W_CBS1585 rna-NM_001182710.1_CBS1585 cds-NP_013930.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:644926-646089:+ gene-YMR203W_CBS436 rna-NM_001182710.1_CBS436 cds-NP_013930.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:752234-753397:+ gene-YMR203W_CBS6412 rna-NM_001182710.1_CBS6412 cds-NP_013930.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:639826-640989:+ gene-YMR203W_CBS6413 rna-NM_001182710.1_CBS6413 cds-NP_013930.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:663178-664341:+ gene-YMR203W_CENPK1137D rna-NM_001182710.1_CENPK1137D cds-NP_013930.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:700882-702045:+ gene-YMR203W_EthanolRed rna-NM_001182710.1_EthanolRed cds-NP_013930.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:646536-647699:+ gene-YMR203W_FaliES1 rna-NM_001182710.1_FaliES1 cds-NP_013930.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000141.1:138336-139499:- gene-YMR203W_JAY291 rna-NM_001182710.1_JAY291 cds-NP_013930.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:646178-647341:+ gene-YMR203W_MUCL30387 rna-NM_001182710.1_MUCL30387 cds-NP_013930.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:652954-654117:+ gene-YMR203W_MUCL30388 rna-NM_001182710.1_MUCL30388 cds-NP_013930.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:641747-642910:+ gene-YMR203W_MUCL39482 rna-NM_001182710.1_MUCL39482 cds-NP_013930.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:649073-650236:+ gene-YMR203W_MUCL42920 rna-NM_001182710.1_MUCL42920 cds-NP_013930.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:668446-669609:+ gene-YMR203W_NCIM3186 rna-NM_001182710.1_NCIM3186 cds-NP_013930.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:641399-642562:+ gene-YMR203W_NCYC1407 rna-NM_001182710.1_NCYC1407 cds-NP_013930.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:651244-652407:+ gene-YMR203W_PE2H3 rna-NM_001182710.1_PE2H3 cds-NP_013930.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:652258-653421:+ gene-YMR203W_PE2H4 rna-NM_001182710.1_PE2H4 cds-NP_013930.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:668492-669655:+ gene-YMR203W_S288C rna-NM_001182710.1_S288C cds-NP_013930.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:138455-139618:- gene-YMR203W_SA1 rna-NM_001182710.1_SA1 cds-NP_013930.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:642707-643870:+ gene-YMR203W_ThermosaccDry rna-NM_001182710.1_ThermosaccDry cds-NP_013930.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:655776-656939:+ gene-YMR203W_VR1 rna-NM_001182710.1_VR1 cds-NP_013930.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:58409-59572:+ gene-YMR203W_ZTW1 rna-NM_001182710.1_ZTW1 cds-NP_013930.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:660521-661684:+ gene-YMR203W_Sparadoxus rna-NM_001182710.1_Sparadoxus cds-NP_013930.1_Sparadoxus 94.6 100.0 Verified 1 1 1 False True False False False

Additional files