Gene name: TOK1
Reference locus (S288C): YJL093C
Gene biotype: protein_coding
Description: Outward-rectifier potassium channel of the plasma membrane; has two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin
Top 10 interactors (score): TRK1 (0.968); NHA1 (0.956); TRK2 (0.956); KHA1 (0.93); ENA1 (0.923); CCH1 (0.83); NHX1 (0.794); YPK1 (0.78); KSP1 (0.78); HAL1 (0.772); VNX1 (0.759); YLH47 (0.717); PHO89 (0.712); KRE1 (0.711); PMA1 (0.705); SIS2 (0.65); YIL029C (0.65); HOG1 (0.642); PMP3 (0.611); PAM1 (0.597)
Homologues (species, bitscore): KCNK10 (Homo sapiens, 71.2); Kcnk10 (Mus musculus, 70.9); LOC563228 (Danio rerio, 67.4); kcnk10 (Xenopus tropicalis, 70.1); Task6 (Drosophila melanogaster, 61.6); twk-40 (Caenorhabditis elegans, 70.1); KCO5 (Arabidopsis thaliana, 69.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:237458-239533:- | gene-YJL093C_AKU4011 | rna-NM_001181526.1_AKU4011 | cds-NP_012442.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:374921-376996:+ | gene-YJL093C_BG1 | rna-NM_001181526.1_BG1 | cds-NP_012442.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:248902-250977:- | gene-YJL093C_Bruggeman | rna-NM_001181526.1_Bruggeman | cds-NP_012442.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:253798-255873:- | gene-YJL093C_CAT1 | rna-NM_001181526.1_CAT1 | cds-NP_012442.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:249119-251194:- | gene-YJL093C_CBS1585 | rna-NM_001181526.1_CBS1585 | cds-NP_012442.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:267226-269301:- | gene-YJL093C_CBS436 | rna-NM_001181526.1_CBS436 | cds-NP_012442.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:238216-240291:- | gene-YJL093C_CBS6412 | rna-NM_001181526.1_CBS6412 | cds-NP_012442.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:239571-241646:- | gene-YJL093C_CBS6413 | rna-NM_001181526.1_CBS6413 | cds-NP_012442.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:237208-239283:- | gene-YJL093C_CENPK1137D | rna-NM_001181526.1_CENPK1137D | cds-NP_012442.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:241305-243380:- | gene-YJL093C_EthanolRed | rna-NM_001181526.1_EthanolRed | cds-NP_012442.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:252882-254957:- | gene-YJL093C_FaliES1 | rna-NM_001181526.1_FaliES1 | cds-NP_012442.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:50498-52573:- | gene-YJL093C_JAY291 | rna-NM_001181526.1_JAY291 | cds-NP_012442.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:251172-253247:- | gene-YJL093C_MUCL30387 | rna-NM_001181526.1_MUCL30387 | cds-NP_012442.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:247247-249322:- | gene-YJL093C_MUCL30388 | rna-NM_001181526.1_MUCL30388 | cds-NP_012442.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:241876-243951:- | gene-YJL093C_MUCL39482 | rna-NM_001181526.1_MUCL39482 | cds-NP_012442.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:248080-250155:- | gene-YJL093C_MUCL42920 | rna-NM_001181526.1_MUCL42920 | cds-NP_012442.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:254716-256791:- | gene-YJL093C_NCIM3186 | rna-NM_001181526.1_NCIM3186 | cds-NP_012442.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:240564-242639:- | gene-YJL093C_NCYC1407 | rna-NM_001181526.1_NCYC1407 | cds-NP_012442.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:252924-254999:- | gene-YJL093C_PE2H3 | rna-NM_001181526.1_PE2H3 | cds-NP_012442.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:252568-254643:- | gene-YJL093C_PE2H4 | rna-NM_001181526.1_PE2H4 | cds-NP_012442.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:254737-256812:- | gene-YJL093C_S288C | rna-NM_001181526.1_S288C | cds-NP_012442.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:50439-52514:- | gene-YJL093C_SA1 | rna-NM_001181526.1_SA1 | cds-NP_012442.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:246291-248366:- | gene-YJL093C_ThermosaccDry | rna-NM_001181526.1_ThermosaccDry | cds-NP_012442.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:247800-249875:- | gene-YJL093C_VR1 | rna-NM_001181526.1_VR1 | cds-NP_012442.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:227652-229727:- | gene-YJL093C_ZTW1 | rna-NM_001181526.1_ZTW1 | cds-NP_012442.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:251739-253814:- | gene-YJL093C_Sparadoxus | rna-NM_001181526.1_Sparadoxus | cds-NP_012442.1_Sparadoxus | 88.9 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |