TOA2 (YKL058W)


Gene profile

Gene name: TOA2
Reference locus (S288C): YKL058W
Gene biotype: protein_coding

Description: TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa1p, for ribosomal protein gene transcription in vivo; homologous to smallest subunit of human and Drosophila TFIIA; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): SPT15 (0.999); TOA1 (0.999); SUA7 (0.998); TFA1 (0.996); TFG1 (0.996); RPB10 (0.995); TFA2 (0.995); SSL2 (0.994); RPO21 (0.994); RPB11 (0.993); TFG2 (0.988); TAF1 (0.987); TAF13 (0.98); RAD3 (0.977); RPB5 (0.977); NUT2 (0.977); RPB2 (0.975); RPB3 (0.973); RPO26 (0.972); TFB5 (0.971)

Homologues (species, bitscore): GTF2A2 (Homo sapiens, 88.6); Gtf2a2 (Mus musculus, 88.6); gtf2a2 (Danio rerio, 87.0); gtf2a2 (Xenopus tropicalis, 87.4); TfIIA-S (Drosophila melanogaster, 85.5); Y111B2A.13 (Caenorhabditis elegans, 75.5); AT4G24440 (Arabidopsis thaliana, 92.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:316141-316509:+ gene-YKL058W_AKU4011 rna-NM_001179624.1_AKU4011 cds-NP_012865.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:327443-327811:- gene-YKL058W_BG1 rna-NM_001179624.1_BG1 cds-NP_012865.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:335179-335547:+ gene-YKL058W_Bruggeman rna-NM_001179624.1_Bruggeman cds-NP_012865.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:331617-331985:+ gene-YKL058W_CAT1 rna-NM_001179624.1_CAT1 cds-NP_012865.1_CAT1 99.4 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:328871-329239:+ gene-YKL058W_CBS1585 rna-NM_001179624.1_CBS1585 cds-NP_012865.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:327025-327393:+ gene-YKL058W_CBS436 rna-NM_001179624.1_CBS436 cds-NP_012865.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:313012-313380:+ gene-YKL058W_CBS6412 rna-NM_001179624.1_CBS6412 cds-NP_012865.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:328837-329205:+ gene-YKL058W_CBS6413 rna-NM_001179624.1_CBS6413 cds-NP_012865.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:329827-330195:+ gene-YKL058W_CENPK1137D rna-NM_001179624.1_CENPK1137D cds-NP_012865.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:326844-327212:+ gene-YKL058W_EthanolRed rna-NM_001179624.1_EthanolRed cds-NP_012865.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:327657-328025:+ gene-YKL058W_FaliES1 rna-NM_001179624.1_FaliES1 cds-NP_012865.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000080.1:32587-32955:+ gene-YKL058W_JAY291 rna-NM_001179624.1_JAY291 cds-NP_012865.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:336090-336458:+ gene-YKL058W_MUCL30387 rna-NM_001179624.1_MUCL30387 cds-NP_012865.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:330989-331357:+ gene-YKL058W_MUCL30388 rna-NM_001179624.1_MUCL30388 cds-NP_012865.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:328167-328535:+ gene-YKL058W_MUCL39482 rna-NM_001179624.1_MUCL39482 cds-NP_012865.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:333077-333445:+ gene-YKL058W_MUCL42920 rna-NM_001179624.1_MUCL42920 cds-NP_012865.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:330155-330523:+ gene-YKL058W_NCIM3186 rna-NM_001179624.1_NCIM3186 cds-NP_012865.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:328364-328732:+ gene-YKL058W_NCYC1407 rna-NM_001179624.1_NCYC1407 cds-NP_012865.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:352928-353296:+ gene-YKL058W_PE2H3 rna-NM_001179624.1_PE2H3 cds-NP_012865.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:337668-338036:+ gene-YKL058W_PE2H4 rna-NM_001179624.1_PE2H4 cds-NP_012865.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:330166-330534:+ gene-YKL058W_S288C rna-NM_001179624.1_S288C cds-NP_012865.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:8164-8532:+ gene-YKL058W_SA1 rna-NM_001179624.1_SA1 cds-NP_012865.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:328847-329215:+ gene-YKL058W_ThermosaccDry rna-NM_001179624.1_ThermosaccDry cds-NP_012865.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:327993-328361:+ gene-YKL058W_VR1 rna-NM_001179624.1_VR1 cds-NP_012865.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:326892-327260:+ gene-YKL058W_ZTW1 rna-NM_001179624.1_ZTW1 cds-NP_012865.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:346086-346454:+ gene-YKL058W_Sparadoxus rna-NM_001179624.1_Sparadoxus cds-NP_012865.1_Sparadoxus 93.7 100.0 Verified 1 1 1 False True False False False

Additional files