TOA1 (YOR194C)


Gene profile

Gene name: TOA1
Reference locus (S288C): YOR194C
Gene biotype: protein_coding

Description: TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa2p, for ribosomal protein gene transcription in vivo; homologous to largest and second largest subunits of human and Drosophila TFIIA; Belongs to the TFIIA subunit 1 family

Top 10 interactors (score): TOA2 (0.999); SPT15 (0.999); SUA7 (0.999); TFA1 (0.999); TFG1 (0.998); RPO21 (0.998); TFA2 (0.993); SSL2 (0.987); TFB5 (0.983); TFB3 (0.977); TFG2 (0.967); RPO26 (0.965); RAD3 (0.961); RPB5 (0.959); RPB4 (0.958); RPB10 (0.957); RPB9 (0.955); RPB2 (0.954); GCN5 (0.95); RPB3 (0.949)

Homologues (species, bitscore): GTF2A1 (Homo sapiens, 73.6); Gtf2a1 (Mus musculus, 73.9); gtf2a1 (Danio rerio, 75.9); gtf2a1 (Xenopus tropicalis, 62.8); TfIIA-L (Drosophila melanogaster, 71.6); pqn-51 (Caenorhabditis elegans, 63.9); AT1G07480 (Arabidopsis thaliana, 65.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:702468-703328:- gene-YOR194C_AKU4011 rna-NM_001183613.1_AKU4011 cds-NP_014837.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:104508-105368:- gene-YOR194C_BG1 rna-NM_001183613.1_BG1 cds-NP_014837.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:687299-688159:- gene-YOR194C_Bruggeman rna-NM_001183613.1_Bruggeman cds-NP_014837.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:688582-689442:- gene-YOR194C_CAT1 rna-NM_001183613.1_CAT1 cds-NP_014837.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:685455-686315:- gene-YOR194C_CBS1585 rna-NM_001183613.1_CBS1585 cds-NP_014837.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:684145-685005:- gene-YOR194C_CBS436 rna-NM_001183613.1_CBS436 cds-NP_014837.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:682573-683433:- gene-YOR194C_CBS6412 rna-NM_001183613.1_CBS6412 cds-NP_014837.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:691212-692072:- gene-YOR194C_CBS6413 rna-NM_001183613.1_CBS6413 cds-NP_014837.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:711438-712298:- gene-YOR194C_CENPK1137D rna-NM_001183613.1_CENPK1137D cds-NP_014837.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:678598-679458:- gene-YOR194C_EthanolRed rna-NM_001183613.1_EthanolRed cds-NP_014837.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:683995-684855:- gene-YOR194C_FaliES1 rna-NM_001183613.1_FaliES1 cds-NP_014837.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:141892-142752:+ gene-YOR194C_JAY291 rna-NM_001183613.1_JAY291 cds-NP_014837.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:691265-692125:- gene-YOR194C_MUCL30387 rna-NM_001183613.1_MUCL30387 cds-NP_014837.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:698683-699543:- gene-YOR194C_MUCL30388 rna-NM_001183613.1_MUCL30388 cds-NP_014837.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:692784-693644:- gene-YOR194C_MUCL39482 rna-NM_001183613.1_MUCL39482 cds-NP_014837.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:702368-703228:- gene-YOR194C_MUCL42920 rna-NM_001183613.1_MUCL42920 cds-NP_014837.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:711572-712432:- gene-YOR194C_NCIM3186 rna-NM_001183613.1_NCIM3186 cds-NP_014837.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:692882-693742:- gene-YOR194C_NCYC1407 rna-NM_001183613.1_NCYC1407 cds-NP_014837.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:692281-693141:- gene-YOR194C_PE2H3 rna-NM_001183613.1_PE2H3 cds-NP_014837.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:702658-703518:- gene-YOR194C_PE2H4 rna-NM_001183613.1_PE2H4 cds-NP_014837.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:711683-712543:- gene-YOR194C_S288C rna-NM_001183613.1_S288C cds-NP_014837.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:121688-122548:- gene-YOR194C_SA1 rna-NM_001183613.1_SA1 cds-NP_014837.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:683180-684040:- gene-YOR194C_ThermosaccDry rna-NM_001183613.1_ThermosaccDry cds-NP_014837.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:746721-747581:- gene-YOR194C_VR1 rna-NM_001183613.1_VR1 cds-NP_014837.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:416096-416956:- gene-YOR194C_ZTW1 rna-NM_001183613.1_ZTW1 cds-NP_014837.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:689088-689948:- gene-YOR194C_Sparadoxus rna-NM_001183613.1_Sparadoxus cds-NP_014837.1_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files