Gene name: TMT1
Reference locus (S288C): YER175C
Gene biotype: protein_coding
Description: Trans-aconitate methyltransferase; cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle; Belongs to the methyltransferase superfamily. Tam family
Top 10 interactors (score): YGL117W (0.974); STR2 (0.873); ARG4 (0.829); FMP23 (0.814); PKP2 (0.797); ARG7 (0.743); ORT1 (0.696); ARG1 (0.655); ARG5,6 (0.653); YBR225W (0.65); SRL4 (0.632); MCH4 (0.609); RIB5 (0.608); MHT1 (0.601); RTC2 (0.593); GGC1 (0.589); SPE4 (0.565); YML020W (0.56); COQ5 (0.56); GLO4 (0.534)
Homologues (species, bitscore): zgc:162396 (Danio rerio, 78.6); ENSXETP00000060606 (Xenopus tropicalis, 63.2); AT5G10830 (Arabidopsis thaliana, 72.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:520985-521884:- | gene-YER175C_AKU4011 | rna-NM_001179065.3_AKU4011 | cds-NP_011102.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000176.1:11482-12381:+ | gene-YER175C_BG1 | rna-NM_001179065.3_BG1 | cds-NP_011102.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:533728-534627:- | gene-YER175C_Bruggeman | rna-NM_001179065.3_Bruggeman | cds-NP_011102.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:520316-521215:- | gene-YER175C_CAT1 | rna-NM_001179065.3_CAT1 | cds-NP_011102.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:520792-521691:- | gene-YER175C_CBS1585 | rna-NM_001179065.3_CBS1585 | cds-NP_011102.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:530685-531584:- | gene-YER175C_CBS436 | rna-NM_001179065.3_CBS436 | cds-NP_011102.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:518769-519668:- | gene-YER175C_CBS6412 | rna-NM_001179065.3_CBS6412 | cds-NP_011102.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:527338-528237:- | gene-YER175C_CBS6413 | rna-NM_001179065.3_CBS6413 | cds-NP_011102.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:537233-538132:- | gene-YER175C_CENPK1137D | rna-NM_001179065.3_CENPK1137D | cds-NP_011102.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:526960-527859:- | gene-YER175C_EthanolRed | rna-NM_001179065.3_EthanolRed | cds-NP_011102.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:527896-528795:- | gene-YER175C_FaliES1 | rna-NM_001179065.3_FaliES1 | cds-NP_011102.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000169.1:11111-12010:+ | gene-YER175C_JAY291 | rna-NM_001179065.3_JAY291 | cds-NP_011102.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:521041-521940:- | gene-YER175C_MUCL30387 | rna-NM_001179065.3_MUCL30387 | cds-NP_011102.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:523957-524856:- | gene-YER175C_MUCL30388 | rna-NM_001179065.3_MUCL30388 | cds-NP_011102.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:516750-517649:- | gene-YER175C_MUCL39482 | rna-NM_001179065.3_MUCL39482 | cds-NP_011102.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:531273-532172:- | gene-YER175C_MUCL42920 | rna-NM_001179065.3_MUCL42920 | cds-NP_011102.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:539463-540362:- | gene-YER175C_NCIM3186 | rna-NM_001179065.3_NCIM3186 | cds-NP_011102.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:526205-527104:- | gene-YER175C_NCYC1407 | rna-NM_001179065.3_NCYC1407 | cds-NP_011102.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:542139-543038:- | gene-YER175C_PE2H3 | rna-NM_001179065.3_PE2H3 | cds-NP_011102.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:532079-532978:- | gene-YER175C_PE2H4 | rna-NM_001179065.3_PE2H4 | cds-NP_011102.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:539464-540363:- | gene-YER175C_S288C | rna-NM_001179065.3_S288C | cds-NP_011102.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000030.1:91616-92515:- | gene-YER175C_SA1 | rna-NM_001179065.3_SA1 | cds-NP_011102.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:528696-529595:- | gene-YER175C_ThermosaccDry | rna-NM_001179065.3_ThermosaccDry | cds-NP_011102.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:521982-522881:- | gene-YER175C_VR1 | rna-NM_001179065.3_VR1 | cds-NP_011102.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000011.1:41542-42441:- | gene-YER175C_ZTW1 | rna-NM_001179065.3_ZTW1 | cds-NP_011102.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:529927-530826:- | gene-YER175C_Sparadoxus | rna-NM_001179065.3_Sparadoxus | cds-NP_011102.3_Sparadoxus | 86.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |