Gene name: TML25
Reference locus (S288C): YLR118C
Gene biotype: protein_coding
Description: Phospholipase/carboxylesterase; Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family
Top 10 interactors (score): NCP1 (0.9); YNL320W (0.869); RCE1 (0.846); NIF3 (0.758); YMR087W (0.75); PXP2 (0.717); SUA5 (0.707); MEU1 (0.686); MXR1 (0.652); SPO14 (0.647); NMT1 (0.63); HBN1 (0.615); BNA3 (0.612); APT2 (0.605); APT1 (0.605); YJL068C (0.605); AKR1 (0.604); SAY1 (0.593); DIA4 (0.591); MOD5 (0.59)
Homologues (species, bitscore): LYPLA2 (Homo sapiens, 140.2); Lypla1 (Mus musculus, 139.4); lypla1 (Danio rerio, 147.5); lypla1 (Xenopus tropicalis, 136.7); CG18815 (Drosophila melanogaster, 129.4); ath-1 (Caenorhabditis elegans, 129.4); SOBER1 (Arabidopsis thaliana, 120.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:367208-367891:- | gene-YLR118C_AKU4011 | rna-NM_001182005.1_AKU4011 | cds-NP_013219.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:330986-331669:- | gene-YLR118C_BG1 | rna-NM_001182005.1_BG1 | cds-NP_013219.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:378332-379015:- | gene-YLR118C_Bruggeman | rna-NM_001182005.1_Bruggeman | cds-NP_013219.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:378249-378932:- | gene-YLR118C_CAT1 | rna-NM_001182005.1_CAT1 | cds-NP_013219.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:374351-375034:- | gene-YLR118C_CBS1585 | rna-NM_001182005.1_CBS1585 | cds-NP_013219.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:364591-365274:- | gene-YLR118C_CBS436 | rna-NM_001182005.1_CBS436 | cds-NP_013219.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:372769-373452:- | gene-YLR118C_CBS6412 | rna-NM_001182005.1_CBS6412 | cds-NP_013219.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:374617-375300:- | gene-YLR118C_CBS6413 | rna-NM_001182005.1_CBS6413 | cds-NP_013219.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:369747-370430:- | gene-YLR118C_CENPK1137D | rna-NM_001182005.1_CENPK1137D | cds-NP_013219.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:367408-368091:- | gene-YLR118C_EthanolRed | rna-NM_001182005.1_EthanolRed | cds-NP_013219.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:366919-367602:- | gene-YLR118C_FaliES1 | rna-NM_001182005.1_FaliES1 | cds-NP_013219.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000117.1:25593-26276:+ | gene-YLR118C_JAY291 | rna-NM_001182005.1_JAY291 | cds-NP_013219.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:374624-375307:- | gene-YLR118C_MUCL30387 | rna-NM_001182005.1_MUCL30387 | cds-NP_013219.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:383405-384088:- | gene-YLR118C_MUCL30388 | rna-NM_001182005.1_MUCL30388 | cds-NP_013219.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:374860-375543:- | gene-YLR118C_MUCL39482 | rna-NM_001182005.1_MUCL39482 | cds-NP_013219.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:374986-375669:- | gene-YLR118C_MUCL42920 | rna-NM_001182005.1_MUCL42920 | cds-NP_013219.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:384699-385382:- | gene-YLR118C_NCIM3186 | rna-NM_001182005.1_NCIM3186 | cds-NP_013219.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:367133-367816:- | gene-YLR118C_NCYC1407 | rna-NM_001182005.1_NCYC1407 | cds-NP_013219.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:372696-373379:- | gene-YLR118C_PE2H3 | rna-NM_001182005.1_PE2H3 | cds-NP_013219.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:372437-373120:- | gene-YLR118C_PE2H4 | rna-NM_001182005.1_PE2H4 | cds-NP_013219.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:384725-385408:- | gene-YLR118C_S288C | rna-NM_001182005.1_S288C | cds-NP_013219.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:10600-11283:- | gene-YLR118C_SA1 | rna-NM_001182005.1_SA1 | cds-NP_013219.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:368129-368812:- | gene-YLR118C_ThermosaccDry | rna-NM_001182005.1_ThermosaccDry | cds-NP_013219.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:380591-381274:- | gene-YLR118C_VR1 | rna-NM_001182005.1_VR1 | cds-NP_013219.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:365927-366610:- | gene-YLR118C_ZTW1 | rna-NM_001182005.1_ZTW1 | cds-NP_013219.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:375762-376445:- | gene-YLR118C_Sparadoxus | rna-NM_001182005.1_Sparadoxus | cds-NP_013219.1_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |