Gene name: TMC1
Reference locus (S288C): YOR052C
Gene biotype: protein_coding
Description: AN1-type zinc finger protein, effector of proteotoxic stress response; stress-inducible transcriptional target of Rpn4p; induced by nitrogen limitation, weak acid, misfolded proteins; short-lived protein, degraded by proteasome; may protect cells from trivalent metalloid induced proteotoxicity; contains PACE promoter element; ortholog of human AIRAP, which stimulates proteasome activity in response to arsenic; protein abundance increases under DNA replication stress
Top 10 interactors (score): YLR363W-A (0.865); GCG1 (0.746); YBR062C (0.739); YDR090C (0.695); YFR016C (0.672); YMR196W (0.65); YPL247C (0.648); CUZ1 (0.647); HSP42 (0.645); YHR097C (0.636); NMD4 (0.613); NSG2 (0.61); RCN2 (0.608); EDC2 (0.593); YMR295C (0.59); YCR023C (0.574); MLF3 (0.574); YBR085C-A (0.572); RBS1 (0.562); VNX1 (0.552)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:411117-411569:- | gene-YOR052C_AKU4011 | rna-NM_001183471.1_AKU4011 | cds-NP_014695.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000124.1:158-610:- | gene-YOR052C_BG1 | rna-NM_001183471.1_BG1 | cds-NP_014695.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:413839-414291:- | gene-YOR052C_Bruggeman | rna-NM_001183471.1_Bruggeman | cds-NP_014695.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:412031-412483:- | gene-YOR052C_CAT1 | rna-NM_001183471.1_CAT1 | cds-NP_014695.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:405808-406260:- | gene-YOR052C_CBS1585 | rna-NM_001183471.1_CBS1585 | cds-NP_014695.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:410161-410613:- | gene-YOR052C_CBS436 | rna-NM_001183471.1_CBS436 | cds-NP_014695.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:405159-405611:- | gene-YOR052C_CBS6412 | rna-NM_001183471.1_CBS6412 | cds-NP_014695.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:412536-412988:- | gene-YOR052C_CBS6413 | rna-NM_001183471.1_CBS6413 | cds-NP_014695.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:426768-427220:- | gene-YOR052C_CENPK1137D | rna-NM_001183471.1_CENPK1137D | cds-NP_014695.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:407813-408265:- | gene-YOR052C_EthanolRed | rna-NM_001183471.1_EthanolRed | cds-NP_014695.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:411160-411612:- | gene-YOR052C_FaliES1 | rna-NM_001183471.1_FaliES1 | cds-NP_014695.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:81822-82274:- | gene-YOR052C_JAY291 | rna-NM_001183471.1_JAY291 | cds-NP_014695.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:418634-419086:- | gene-YOR052C_MUCL30387 | rna-NM_001183471.1_MUCL30387 | cds-NP_014695.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:423018-423470:- | gene-YOR052C_MUCL30388 | rna-NM_001183471.1_MUCL30388 | cds-NP_014695.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:413291-413743:- | gene-YOR052C_MUCL39482 | rna-NM_001183471.1_MUCL39482 | cds-NP_014695.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:428117-428569:- | gene-YOR052C_MUCL42920 | rna-NM_001183471.1_MUCL42920 | cds-NP_014695.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:426661-427113:- | gene-YOR052C_NCIM3186 | rna-NM_001183471.1_NCIM3186 | cds-NP_014695.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:419991-420443:- | gene-YOR052C_NCYC1407 | rna-NM_001183471.1_NCYC1407 | cds-NP_014695.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:418847-419299:- | gene-YOR052C_PE2H3 | rna-NM_001183471.1_PE2H3 | cds-NP_014695.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:429228-429680:- | gene-YOR052C_PE2H4 | rna-NM_001183471.1_PE2H4 | cds-NP_014695.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:426772-427224:- | gene-YOR052C_S288C | rna-NM_001183471.1_S288C | cds-NP_014695.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:394714-395166:- | gene-YOR052C_SA1 | rna-NM_001183471.1_SA1 | cds-NP_014695.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:409700-410152:- | gene-YOR052C_ThermosaccDry | rna-NM_001183471.1_ThermosaccDry | cds-NP_014695.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:411170-411622:- | gene-YOR052C_VR1 | rna-NM_001183471.1_VR1 | cds-NP_014695.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:144342-144794:- | gene-YOR052C_ZTW1 | rna-NM_001183471.1_ZTW1 | cds-NP_014695.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:417218-417670:- | gene-YOR052C_Sparadoxus | rna-NM_001183471.1_Sparadoxus | cds-NP_014695.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |