Gene name: TLG2
Reference locus (S288C): YOL018C
Gene biotype: protein_coding
Description: t-SNARE affecting a late Golgi compartment protein 2; Syntaxin-like t-SNARE; forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; required along with VPS45 for an early step of the constitutive CVT pathway; interactions with Vps45 prevents Tlg2p degradation, and facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)
Top 10 interactors (score): TLG1 (0.999); VTI1 (0.999); VPS45 (0.999); SEC17 (0.997); SNC1 (0.997); SNC2 (0.997); SSO1 (0.995); YKT6 (0.994); SED5 (0.994); GOS1 (0.988); VAM7 (0.976); SEC22 (0.975); SEC9 (0.974); COG8 (0.973); YPT6 (0.972); VPS54 (0.969); UFE1 (0.968); VPS53 (0.954); BET1 (0.948); SEC18 (0.943)
Homologues (species, bitscore): STX16 (Homo sapiens, 94.4); Stx16 (Mus musculus, 91.7); stx16 (Danio rerio, 97.1); stx16 (Xenopus tropicalis, 98.6); Syx16 (Drosophila melanogaster, 78.6); syn-16 (Caenorhabditis elegans, 90.9); SYP43 (Arabidopsis thaliana, 108.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:275269-276462:- | gene-YOL018C_AKU4011 | rna-NM_001183272.1_AKU4011 | cds-NP_014624.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:90856-92049:- | gene-YOL018C_BG1 | rna-NM_001183272.1_BG1 | cds-NP_014624.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:278096-279289:- | gene-YOL018C_Bruggeman | rna-NM_001183272.1_Bruggeman | cds-NP_014624.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:275968-277161:- | gene-YOL018C_CAT1 | rna-NM_001183272.1_CAT1 | cds-NP_014624.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:269947-271140:- | gene-YOL018C_CBS1585 | rna-NM_001183272.1_CBS1585 | cds-NP_014624.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:274186-275379:- | gene-YOL018C_CBS436 | rna-NM_001183272.1_CBS436 | cds-NP_014624.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:269303-270496:- | gene-YOL018C_CBS6412 | rna-NM_001183272.1_CBS6412 | cds-NP_014624.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:276830-278023:- | gene-YOL018C_CBS6413 | rna-NM_001183272.1_CBS6413 | cds-NP_014624.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:290580-291773:- | gene-YOL018C_CENPK1137D | rna-NM_001183272.1_CENPK1137D | cds-NP_014624.1_CENPK1137D | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:272098-273291:- | gene-YOL018C_EthanolRed | rna-NM_001183272.1_EthanolRed | cds-NP_014624.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:275425-276618:- | gene-YOL018C_FaliES1 | rna-NM_001183272.1_FaliES1 | cds-NP_014624.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000131.1:2684-3877:- | gene-YOL018C_JAY291 | rna-NM_001183272.1_JAY291 | cds-NP_014624.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:282275-283468:- | gene-YOL018C_MUCL30387 | rna-NM_001183272.1_MUCL30387 | cds-NP_014624.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:285469-286662:- | gene-YOL018C_MUCL30388 | rna-NM_001183272.1_MUCL30388 | cds-NP_014624.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:277432-278625:- | gene-YOL018C_MUCL39482 | rna-NM_001183272.1_MUCL39482 | cds-NP_014624.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:292353-293546:- | gene-YOL018C_MUCL42920 | rna-NM_001183272.1_MUCL42920 | cds-NP_014624.1_MUCL42920 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:290770-291963:- | gene-YOL018C_NCIM3186 | rna-NM_001183272.1_NCIM3186 | cds-NP_014624.1_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:284164-285357:- | gene-YOL018C_NCYC1407 | rna-NM_001183272.1_NCYC1407 | cds-NP_014624.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:266550-267743:- | gene-YOL018C_PE2H3 | rna-NM_001183272.1_PE2H3 | cds-NP_014624.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:277524-278717:- | gene-YOL018C_PE2H4 | rna-NM_001183272.1_PE2H4 | cds-NP_014624.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:290881-292074:- | gene-YOL018C_S288C | rna-NM_001183272.1_S288C | cds-NP_014624.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:258876-260069:- | gene-YOL018C_SA1 | rna-NM_001183272.1_SA1 | cds-NP_014624.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:273996-275189:- | gene-YOL018C_ThermosaccDry | rna-NM_001183272.1_ThermosaccDry | cds-NP_014624.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:274033-275226:- | gene-YOL018C_VR1 | rna-NM_001183272.1_VR1 | cds-NP_014624.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:8645-9838:- | gene-YOL018C_ZTW1 | rna-NM_001183272.1_ZTW1 | cds-NP_014624.1_ZTW1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:282021-283211:- | gene-YOL018C_Sparadoxus | rna-NM_001183272.1_Sparadoxus | cds-NP_014624.1_Sparadoxus | 89.3 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |