TLG1 (YDR468C)


Gene profile

Gene name: TLG1
Reference locus (S288C): YDR468C
Gene biotype: protein_coding

Description: Essential t-SNARE that mediates fusion of vesicles with the late Golgi; forms a complex with Tlg2p and Vti1p; mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p; Belongs to the syntaxin family

Top 10 interactors (score): SNC2 (0.999); SNC1 (0.999); TLG2 (0.999); VTI1 (0.999); PEP12 (0.998); SED5 (0.998); VPS45 (0.997); GOS1 (0.994); VPS51 (0.994); YKT6 (0.993); YPT6 (0.988); SEC22 (0.982); BOS1 (0.981); VAM3 (0.981); SSO1 (0.979); SEC17 (0.979); BET1 (0.973); VPS54 (0.97); SEC9 (0.96); NYV1 (0.96)

Homologues (species, bitscore): stx6 (Danio rerio, 54.3); SYP61 (Arabidopsis thaliana, 58.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1337947-1338621:- gene-YDR468C_AKU4011 rna-NM_001180776.3_AKU4011 cds-NP_010756.3_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:213053-213727:- gene-YDR468C_BG1 rna-NM_001180776.3_BG1 cds-NP_010756.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1369359-1370033:- gene-YDR468C_Bruggeman rna-NM_001180776.3_Bruggeman cds-NP_010756.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1346503-1347177:- gene-YDR468C_CAT1 rna-NM_001180776.3_CAT1 cds-NP_010756.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1332243-1332917:- gene-YDR468C_CBS1585 rna-NM_001180776.3_CBS1585 cds-NP_010756.3_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1351611-1352285:- gene-YDR468C_CBS436 rna-NM_001180776.3_CBS436 cds-NP_010756.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1327870-1328544:- gene-YDR468C_CBS6412 rna-NM_001180776.3_CBS6412 cds-NP_010756.3_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1350881-1351555:- gene-YDR468C_CBS6413 rna-NM_001180776.3_CBS6413 cds-NP_010756.3_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1396722-1397396:- gene-YDR468C_CENPK1137D rna-NM_001180776.3_CENPK1137D cds-NP_010756.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1341285-1341959:- gene-YDR468C_EthanolRed rna-NM_001180776.3_EthanolRed cds-NP_010756.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1344838-1345512:- gene-YDR468C_FaliES1 rna-NM_001180776.3_FaliES1 cds-NP_010756.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:43095-43769:- gene-YDR468C_JAY291 rna-NM_001180776.3_JAY291 cds-NP_010756.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1351851-1352525:- gene-YDR468C_MUCL30387 rna-NM_001180776.3_MUCL30387 cds-NP_010756.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1333873-1334547:- gene-YDR468C_MUCL30388 rna-NM_001180776.3_MUCL30388 cds-NP_010756.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1323727-1324401:- gene-YDR468C_MUCL39482 rna-NM_001180776.3_MUCL39482 cds-NP_010756.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1266527-1267201:- gene-YDR468C_MUCL42920 rna-NM_001180776.3_MUCL42920 cds-NP_010756.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1397949-1398623:- gene-YDR468C_NCIM3186 rna-NM_001180776.3_NCIM3186 cds-NP_010756.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1337500-1338174:- gene-YDR468C_NCYC1407 rna-NM_001180776.3_NCYC1407 cds-NP_010756.3_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1348346-1349020:- gene-YDR468C_PE2H3 rna-NM_001180776.3_PE2H3 cds-NP_010756.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1353919-1354593:- gene-YDR468C_PE2H4 rna-NM_001180776.3_PE2H4 cds-NP_010756.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1398026-1398700:- gene-YDR468C_S288C rna-NM_001180776.3_S288C cds-NP_010756.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:218460-219134:+ gene-YDR468C_SA1 rna-NM_001180776.3_SA1 cds-NP_010756.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1349060-1349734:- gene-YDR468C_ThermosaccDry rna-NM_001180776.3_ThermosaccDry cds-NP_010756.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1364789-1365463:- gene-YDR468C_VR1 rna-NM_001180776.3_VR1 cds-NP_010756.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:391732-392406:- gene-YDR468C_ZTW1 rna-NM_001180776.3_ZTW1 cds-NP_010756.3_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1352111-1352785:- gene-YDR468C_Sparadoxus rna-NM_001180776.3_Sparadoxus cds-NP_010756.3_Sparadoxus 90.2 99.8 Verified 1 1 1 False True False False False

Additional files