Gene name: TKL2
Reference locus (S288C): YBR117C
Gene biotype: protein_coding
Description: Transketolase; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids; TKL2 has a paralog, TKL1, that arose from the whole genome duplication
Top 10 interactors (score): TAL1 (0.999); NQM1 (0.999); TKL1 (0.999); RPE1 (0.999); TPI1 (0.998); GND2 (0.997); RKI1 (0.995); YBR116C (0.988); ALD3 (0.987); PGI1 (0.987); FBP1 (0.976); HBT1 (0.975); CTT1 (0.974); SOL4 (0.973); RBK1 (0.97); GRE1 (0.969); FBA1 (0.968); HXT5 (0.968); PGM2 (0.966); PGM1 (0.96)
Homologues (species, bitscore): TKT (Homo sapiens, 146.7); Tktl2 (Mus musculus, 141.0); tktb (Danio rerio, 137.5); tktl2 (Xenopus tropicalis, 144.8); CG8036 (Drosophila melanogaster, 159.5); tkt-1 (Caenorhabditis elegans, 137.9); AT3G60750 (Arabidopsis thaliana, 618.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:456790-458835:- | gene-YBR117C_AKU4011 | rna-NM_001178465.3_AKU4011 | cds-NP_009675.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:447824-449869:- | gene-YBR117C_BG1 | rna-NM_001178465.3_BG1 | cds-NP_009675.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:458563-460608:- | gene-YBR117C_Bruggeman | rna-NM_001178465.3_Bruggeman | cds-NP_009675.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:461782-463827:- | gene-YBR117C_CAT1 | rna-NM_001178465.3_CAT1 | cds-NP_009675.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:449073-451118:- | gene-YBR117C_CBS1585 | rna-NM_001178465.3_CBS1585 | cds-NP_009675.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:457140-459185:- | gene-YBR117C_CBS436 | rna-NM_001178465.3_CBS436 | cds-NP_009675.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:547302-549347:- | gene-YBR117C_CBS6412 | rna-NM_001178465.3_CBS6412 | cds-NP_009675.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:454202-456247:- | gene-YBR117C_CBS6413 | rna-NM_001178465.3_CBS6413 | cds-NP_009675.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:466290-468338:- | gene-YBR117C_CENPK1137D | rna-NM_001178465.3_CENPK1137D | cds-NP_009675.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:583542-585587:- | gene-YBR117C_EthanolRed | rna-NM_001178465.3_EthanolRed | cds-NP_009675.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:472825-474870:- | gene-YBR117C_FaliES1 | rna-NM_001178465.3_FaliES1 | cds-NP_009675.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000312.1:43724-45769:- | gene-YBR117C_JAY291 | rna-NM_001178465.3_JAY291 | cds-NP_009675.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:461221-463266:- | gene-YBR117C_MUCL30387 | rna-NM_001178465.3_MUCL30387 | cds-NP_009675.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:459824-461869:- | gene-YBR117C_MUCL30388 | rna-NM_001178465.3_MUCL30388 | cds-NP_009675.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:447216-449261:- | gene-YBR117C_MUCL39482 | rna-NM_001178465.3_MUCL39482 | cds-NP_009675.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:456878-458923:- | gene-YBR117C_MUCL42920 | rna-NM_001178465.3_MUCL42920 | cds-NP_009675.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:474189-476234:- | gene-YBR117C_NCIM3186 | rna-NM_001178465.3_NCIM3186 | cds-NP_009675.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:449994-452039:- | gene-YBR117C_NCYC1407 | rna-NM_001178465.3_NCYC1407 | cds-NP_009675.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:462569-464614:- | gene-YBR117C_PE2H3 | rna-NM_001178465.3_PE2H3 | cds-NP_009675.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:460245-462290:- | gene-YBR117C_PE2H4 | rna-NM_001178465.3_PE2H4 | cds-NP_009675.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:474392-476437:- | gene-YBR117C_S288C | rna-NM_001178465.3_S288C | cds-NP_009675.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:1319-3364:+ | gene-YBR117C_SA1 | rna-NM_001178465.3_SA1 | cds-NP_009675.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:471832-473877:- | gene-YBR117C_ThermosaccDry | rna-NM_001178465.3_ThermosaccDry | cds-NP_009675.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:453828-455873:- | gene-YBR117C_VR1 | rna-NM_001178465.3_VR1 | cds-NP_009675.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:447482-449527:- | gene-YBR117C_ZTW1 | rna-NM_001178465.3_ZTW1 | cds-NP_009675.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:484654-486699:- | gene-YBR117C_Sparadoxus | rna-NM_001178465.3_Sparadoxus | cds-NP_009675.3_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |