TIM50 (YPL063W)


Gene profile

Gene name: TIM50
Reference locus (S288C): YPL063W
Gene biotype: protein_coding

Description: Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel

Top 10 interactors (score): PAM18 (0.999); PAM16 (0.999); TIM23 (0.999); TIM44 (0.999); TIM21 (0.999); TIM17 (0.999); TOM40 (0.999); MGE1 (0.997); TOM22 (0.997); PAM17 (0.996); SSC1 (0.995); MGR2 (0.993); TIM13 (0.992); TIM10 (0.979); TIM8 (0.977); TIM9 (0.975); MDJ2 (0.974); DIC1 (0.973); TOM20 (0.968); TOM70 (0.964)

Homologues (species, bitscore): TIMM50 (Homo sapiens, 152.5); Timm50 (Mus musculus, 152.1); timm50 (Danio rerio, 157.9); timm50 (Xenopus tropicalis, 151.8); ttm50 (Drosophila melanogaster, 152.1); scpl-4 (Caenorhabditis elegans, 154.5); TIM50 (Arabidopsis thaliana, 166.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:407660-409090:+ gene-YPL063W_AKU4011 rna-NM_001183877.1_AKU4011 cds-NP_015262.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:613338-614768:+ gene-YPL063W_BG1 rna-NM_001183877.1_BG1 cds-NP_015262.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:483988-485418:+ gene-YPL063W_Bruggeman rna-NM_001183877.1_Bruggeman cds-NP_015262.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:524347-525777:+ gene-YPL063W_CAT1 rna-NM_001183877.1_CAT1 cds-NP_015262.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:411733-413163:+ gene-YPL063W_CBS1585 rna-NM_001183877.1_CBS1585 cds-NP_015262.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:426291-427721:+ gene-YPL063W_CBS436 rna-NM_001183877.1_CBS436 cds-NP_015262.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:415922-417352:+ gene-YPL063W_CBS6412 rna-NM_001183877.1_CBS6412 cds-NP_015262.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:408285-409715:+ gene-YPL063W_CBS6413 rna-NM_001183877.1_CBS6413 cds-NP_015262.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:429903-431333:+ gene-YPL063W_CENPK1137D rna-NM_001183877.1_CENPK1137D cds-NP_015262.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:406024-407454:+ gene-YPL063W_EthanolRed rna-NM_001183877.1_EthanolRed cds-NP_015262.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:413854-415284:+ gene-YPL063W_FaliES1 rna-NM_001183877.1_FaliES1 cds-NP_015262.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:22460-23890:+ gene-YPL063W_JAY291 rna-NM_001183877.1_JAY291 cds-NP_015262.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:424818-426248:+ gene-YPL063W_MUCL30387 rna-NM_001183877.1_MUCL30387 cds-NP_015262.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:423904-425334:+ gene-YPL063W_MUCL30388 rna-NM_001183877.1_MUCL30388 cds-NP_015262.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:405062-406492:+ gene-YPL063W_MUCL39482 rna-NM_001183877.1_MUCL39482 cds-NP_015262.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:462926-464356:+ gene-YPL063W_MUCL42920 rna-NM_001183877.1_MUCL42920 cds-NP_015262.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:429922-431352:+ gene-YPL063W_NCIM3186 rna-NM_001183877.1_NCIM3186 cds-NP_015262.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:412345-413775:+ gene-YPL063W_NCYC1407 rna-NM_001183877.1_NCYC1407 cds-NP_015262.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:418952-420382:+ gene-YPL063W_PE2H3 rna-NM_001183877.1_PE2H3 cds-NP_015262.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:418573-420003:+ gene-YPL063W_PE2H4 rna-NM_001183877.1_PE2H4 cds-NP_015262.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:429939-431369:+ gene-YPL063W_S288C rna-NM_001183877.1_S288C cds-NP_015262.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000057.1:52048-53478:+ gene-YPL063W_SA1 rna-NM_001183877.1_SA1 cds-NP_015262.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:413654-415084:+ gene-YPL063W_ThermosaccDry rna-NM_001183877.1_ThermosaccDry cds-NP_015262.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:428663-430093:+ gene-YPL063W_VR1 rna-NM_001183877.1_VR1 cds-NP_015262.1_VR1 99.4 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:412963-414393:+ gene-YPL063W_ZTW1 rna-NM_001183877.1_ZTW1 cds-NP_015262.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:414690-416123:+ gene-YPL063W_Sparadoxus rna-NM_001183877.1_Sparadoxus cds-NP_015262.1_Sparadoxus 91.0 99.7 Verified 1 1 1 False True False False False

Additional files