TIM44 (YIL022W)


Gene profile

Gene name: TIM44
Reference locus (S288C): YIL022W
Gene biotype: protein_coding

Description: Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the TIM23 complex; tethers the import motor and regulatory factors (PAM complex) to the translocation channel (Tim23p-Tim17p core complex); TIM23 complex is short for the translocase of the inner mitochondrial membrane; Belongs to the Tim44 family

Top 10 interactors (score): TIM23 (0.999); PAM18 (0.999); MGE1 (0.999); TIM21 (0.999); TIM17 (0.999); SSC1 (0.999); TIM50 (0.999); PAM16 (0.999); ECM10 (0.996); TOM40 (0.995); MDJ1 (0.994); PAM17 (0.993); TOM22 (0.991); MDJ2 (0.987); TIM54 (0.985); MGR2 (0.984); TOM20 (0.982); SSQ1 (0.972); TIM9 (0.958); RML2 (0.956)

Homologues (species, bitscore): TIMM44 (Homo sapiens, 138.7); Timm44 (Mus musculus, 138.7); Timm44 (Danio rerio, 156.8); timm44 (Xenopus tropicalis, 139.0); CG11779 (Drosophila melanogaster, 157.5); T09B4.9 (Caenorhabditis elegans, 114.0); TIM44-1 (Arabidopsis thaliana, 84.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:309623-310918:+ gene-YIL022W_AKU4011 rna-NM_001179372.1_AKU4011 cds-NP_012242.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:169449-170744:+ gene-YIL022W_BG1 rna-NM_001179372.1_BG1 cds-NP_012242.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:314767-316062:+ gene-YIL022W_Bruggeman rna-NM_001179372.1_Bruggeman cds-NP_012242.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:302183-303478:+ gene-YIL022W_CAT1 rna-NM_001179372.1_CAT1 cds-NP_012242.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:309714-311009:+ gene-YIL022W_CBS1585 rna-NM_001179372.1_CBS1585 cds-NP_012242.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:303147-304442:+ gene-YIL022W_CBS436 rna-NM_001179372.1_CBS436 cds-NP_012242.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:305246-306541:+ gene-YIL022W_CBS6412 rna-NM_001179372.1_CBS6412 cds-NP_012242.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:301628-302923:+ gene-YIL022W_CBS6413 rna-NM_001179372.1_CBS6413 cds-NP_012242.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:303074-304369:+ gene-YIL022W_CENPK1137D rna-NM_001179372.1_CENPK1137D cds-NP_012242.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:292589-293884:+ gene-YIL022W_EthanolRed rna-NM_001179372.1_EthanolRed cds-NP_012242.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:310500-311795:+ gene-YIL022W_FaliES1 rna-NM_001179372.1_FaliES1 cds-NP_012242.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000098.1:5191-6486:- gene-YIL022W_JAY291 rna-NM_001179372.1_JAY291 cds-NP_012242.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:311617-312912:+ gene-YIL022W_MUCL30387 rna-NM_001179372.1_MUCL30387 cds-NP_012242.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:307722-309017:+ gene-YIL022W_MUCL30388 rna-NM_001179372.1_MUCL30388 cds-NP_012242.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:310303-311598:+ gene-YIL022W_MUCL39482 rna-NM_001179372.1_MUCL39482 cds-NP_012242.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:313437-314732:+ gene-YIL022W_MUCL42920 rna-NM_001179372.1_MUCL42920 cds-NP_012242.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:311165-312460:+ gene-YIL022W_NCIM3186 rna-NM_001179372.1_NCIM3186 cds-NP_012242.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:314576-315871:+ gene-YIL022W_NCYC1407 rna-NM_001179372.1_NCYC1407 cds-NP_012242.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:306218-307513:+ gene-YIL022W_PE2H3 rna-NM_001179372.1_PE2H3 cds-NP_012242.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:300924-302219:+ gene-YIL022W_PE2H4 rna-NM_001179372.1_PE2H4 cds-NP_012242.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:311165-312460:+ gene-YIL022W_S288C rna-NM_001179372.1_S288C cds-NP_012242.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:12070-13365:- gene-YIL022W_SA1 rna-NM_001179372.1_SA1 cds-NP_012242.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:309169-310464:+ gene-YIL022W_ThermosaccDry rna-NM_001179372.1_ThermosaccDry cds-NP_012242.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:305806-307101:+ gene-YIL022W_VR1 rna-NM_001179372.1_VR1 cds-NP_012242.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:283589-284884:+ gene-YIL022W_ZTW1 rna-NM_001179372.1_ZTW1 cds-NP_012242.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:304307-305602:+ gene-YIL022W_Sparadoxus rna-NM_001179372.1_Sparadoxus cds-NP_012242.1_Sparadoxus 91.5 100.0 Verified 1 1 1 False True False False False

Additional files