Gene name: TIM22
Reference locus (S288C): YDL217C
Gene biotype: protein_coding
Description: Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane; forms the channel through which proteins are imported; Belongs to the Tim17/Tim22/Tim23 family
Top 10 interactors (score): TIM9 (0.999); TIM10 (0.999); TIM18 (0.999); TIM23 (0.999); TIM54 (0.999); TIM12 (0.999); SDH3 (0.994); TOM40 (0.991); TOM22 (0.987); TOM7 (0.984); TOM70 (0.98); CYT1 (0.97); HSP60 (0.958); TIM13 (0.95); TIM17 (0.948); TIM44 (0.947); AAC1 (0.943); TOM20 (0.941); CYB2 (0.929); TIM8 (0.926)
Homologues (species, bitscore): TIMM22 (Homo sapiens, 89.4); Timm22 (Mus musculus, 93.2); TIMM22 (Danio rerio, 96.7); timm22 (Xenopus tropicalis, 88.6); CG31229 (Drosophila melanogaster, 88.6); tim-22 (Caenorhabditis elegans, 86.7); MEE67 (Arabidopsis thaliana, 89.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:51477-52100:- | gene-YDL217C_AKU4011 | rna-NM_001180277.1_AKU4011 | cds-NP_010064.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:14970-15593:+ | gene-YDL217C_BG1 | rna-NM_001180277.1_BG1 | cds-NP_010064.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:67153-67776:- | gene-YDL217C_Bruggeman | rna-NM_001180277.1_Bruggeman | cds-NP_010064.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:287003-287626:- | gene-YDL217C_CAT1 | rna-NM_001180277.1_CAT1 | cds-NP_010064.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:50352-50975:- | gene-YDL217C_CBS1585 | rna-NM_001180277.1_CBS1585 | cds-NP_010064.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:265234-265857:- | gene-YDL217C_CBS436 | rna-NM_001180277.1_CBS436 | cds-NP_010064.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:50464-51087:- | gene-YDL217C_CBS6412 | rna-NM_001180277.1_CBS6412 | cds-NP_010064.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:67987-68610:- | gene-YDL217C_CBS6413 | rna-NM_001180277.1_CBS6413 | cds-NP_010064.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:66649-67272:- | gene-YDL217C_CENPK1137D | rna-NM_001180277.1_CENPK1137D | cds-NP_010064.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:63925-64548:- | gene-YDL217C_EthanolRed | rna-NM_001180277.1_EthanolRed | cds-NP_010064.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:68252-68875:- | gene-YDL217C_FaliES1 | rna-NM_001180277.1_FaliES1 | cds-NP_010064.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000213.1:22578-23201:- | gene-YDL217C_JAY291 | rna-NM_001180277.1_JAY291 | cds-NP_010064.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:66102-66725:- | gene-YDL217C_MUCL30387 | rna-NM_001180277.1_MUCL30387 | cds-NP_010064.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:273920-274543:- | gene-YDL217C_MUCL30388 | rna-NM_001180277.1_MUCL30388 | cds-NP_010064.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:51195-51818:- | gene-YDL217C_MUCL39482 | rna-NM_001180277.1_MUCL39482 | cds-NP_010064.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:67251-67874:- | gene-YDL217C_MUCL42920 | rna-NM_001180277.1_MUCL42920 | cds-NP_010064.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:67906-68529:- | gene-YDL217C_NCIM3186 | rna-NM_001180277.1_NCIM3186 | cds-NP_010064.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:51151-51774:- | gene-YDL217C_NCYC1407 | rna-NM_001180277.1_NCYC1407 | cds-NP_010064.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:58191-58814:- | gene-YDL217C_PE2H3 | rna-NM_001180277.1_PE2H3 | cds-NP_010064.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:58201-58824:- | gene-YDL217C_PE2H4 | rna-NM_001180277.1_PE2H4 | cds-NP_010064.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:67983-68606:- | gene-YDL217C_S288C | rna-NM_001180277.1_S288C | cds-NP_010064.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000094.1:22386-23009:- | gene-YDL217C_SA1 | rna-NM_001180277.1_SA1 | cds-NP_010064.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:68007-68630:- | gene-YDL217C_ThermosaccDry | rna-NM_001180277.1_ThermosaccDry | cds-NP_010064.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:68958-69581:- | gene-YDL217C_VR1 | rna-NM_001180277.1_VR1 | cds-NP_010064.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:67175-67798:- | gene-YDL217C_ZTW1 | rna-NM_001180277.1_ZTW1 | cds-NP_010064.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:70561-71175:- | gene-YDL217C_Sparadoxus | rna-NM_001180277.1_Sparadoxus | cds-NP_010064.1_Sparadoxus | 88.6 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |