TIF6 (YPR016C)


Gene profile

Gene name: TIF6
Reference locus (S288C): YPR016C
Gene biotype: protein_coding

Description: Eukaryotic translation initiation factor 6; Constituent of 66S pre-ribosomal particles; has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits; Belongs to the eIF-6 family

Top 10 interactors (score): RPL35A (0.999); BRX1 (0.999); NMD3 (0.999); HAS1 (0.999); NOP15 (0.999); LSG1 (0.999); NOP2 (0.999); RPF2 (0.999); RPL2B (0.999); YTM1 (0.999); RPL28 (0.999); NOG1 (0.999); RPP0 (0.999); RPL17A (0.999); RLP7 (0.999); RPL2A (0.999); BUD20 (0.999); RPL19B (0.999); RPL34A (0.999); RPL3 (0.999)

Homologues (species, bitscore): EIF6 (Homo sapiens, 384.8); Eif6 (Mus musculus, 384.8); eif6 (Danio rerio, 382.9); eif6 (Xenopus tropicalis, 229.6); eIF6 (Drosophila melanogaster, 388.3); eif-6 (Caenorhabditis elegans, 323.2); eIF6A (Arabidopsis thaliana, 387.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:563993-564730:- gene-YPR016C_AKU4011 rna-NM_001184113.1_AKU4011 cds-NP_015341.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:332404-333141:+ gene-YPR016C_BG1 rna-NM_001184113.1_BG1 cds-NP_015341.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:641654-642391:- gene-YPR016C_Bruggeman rna-NM_001184113.1_Bruggeman cds-NP_015341.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:685152-685889:- gene-YPR016C_CAT1 rna-NM_001184113.1_CAT1 cds-NP_015341.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:567679-568416:- gene-YPR016C_CBS1585 rna-NM_001184113.1_CBS1585 cds-NP_015341.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:582046-582783:- gene-YPR016C_CBS436 rna-NM_001184113.1_CBS436 cds-NP_015341.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:571428-572165:- gene-YPR016C_CBS6412 rna-NM_001184113.1_CBS6412 cds-NP_015341.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:564142-564879:- gene-YPR016C_CBS6413 rna-NM_001184113.1_CBS6413 cds-NP_015341.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:592305-593042:- gene-YPR016C_CENPK1137D rna-NM_001184113.1_CENPK1137D cds-NP_015341.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:561928-562665:- gene-YPR016C_EthanolRed rna-NM_001184113.1_EthanolRed cds-NP_015341.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:569730-570467:- gene-YPR016C_FaliES1 rna-NM_001184113.1_FaliES1 cds-NP_015341.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000116.1:56976-57713:+ gene-YPR016C_JAY291 rna-NM_001184113.1_JAY291 cds-NP_015341.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:582874-583611:- gene-YPR016C_MUCL30387 rna-NM_001184113.1_MUCL30387 cds-NP_015341.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:581527-582264:- gene-YPR016C_MUCL30388 rna-NM_001184113.1_MUCL30388 cds-NP_015341.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:560920-561657:- gene-YPR016C_MUCL39482 rna-NM_001184113.1_MUCL39482 cds-NP_015341.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:622251-622988:- gene-YPR016C_MUCL42920 rna-NM_001184113.1_MUCL42920 cds-NP_015341.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:592315-593052:- gene-YPR016C_NCIM3186 rna-NM_001184113.1_NCIM3186 cds-NP_015341.1_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:568867-569604:- gene-YPR016C_NCYC1407 rna-NM_001184113.1_NCYC1407 cds-NP_015341.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:575597-576334:- gene-YPR016C_PE2H3 rna-NM_001184113.1_PE2H3 cds-NP_015341.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:575212-575949:- gene-YPR016C_PE2H4 rna-NM_001184113.1_PE2H4 cds-NP_015341.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:592332-593069:- gene-YPR016C_S288C rna-NM_001184113.1_S288C cds-NP_015341.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:107238-107975:+ gene-YPR016C_SA1 rna-NM_001184113.1_SA1 cds-NP_015341.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:569529-570266:- gene-YPR016C_ThermosaccDry rna-NM_001184113.1_ThermosaccDry cds-NP_015341.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:585765-586502:- gene-YPR016C_VR1 rna-NM_001184113.1_VR1 cds-NP_015341.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:568837-569574:- gene-YPR016C_ZTW1 rna-NM_001184113.1_ZTW1 cds-NP_015341.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:568995-569732:- gene-YPR016C_Sparadoxus rna-NM_001184113.1_Sparadoxus cds-NP_015341.1_Sparadoxus 94.7 100.0 Verified 1 1 1 False True False False False

Additional files