Gene name: TIF5
Reference locus (S288C): YPR041W
Gene biotype: protein_coding
Description: Translation initiation factor eIF5; functions both as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP and as a GDP dissociation inhibitor to prevent recycling of eIF2
Top 10 interactors (score): SUI2 (0.999); RPG1 (0.999); PRT1 (0.999); TIF34 (0.999); FUN12 (0.999); SUI1 (0.999); TIF35 (0.999); SUI3 (0.999); TIF11 (0.999); NIP1 (0.999); GCD11 (0.999); GCD6 (0.995); RPS5 (0.993); HCR1 (0.992); RLI1 (0.991); RPS16A (0.986); RPS0A (0.982); TIF4631 (0.981); RPS3 (0.978); RPS13 (0.978)
Homologues (species, bitscore): EIF5 (Homo sapiens, 270.0); Eif5 (Mus musculus, 270.0); eif5 (Danio rerio, 269.2); eif5 (Xenopus tropicalis, 199.5); eIF5 (Drosophila melanogaster, 256.1); C37C3.2 (Caenorhabditis elegans, 235.7); AT1G77840 (Arabidopsis thaliana, 196.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:620389-621606:+ | gene-YPR041W_AKU4011 | rna-NM_001184138.1_AKU4011 | cds-NP_015366.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:276081-277298:- | gene-YPR041W_BG1 | rna-NM_001184138.1_BG1 | cds-NP_015366.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:698026-699243:+ | gene-YPR041W_Bruggeman | rna-NM_001184138.1_Bruggeman | cds-NP_015366.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:740995-742677:+ | gene-YPR041W_CAT1 | rna-NM_001184138.1_CAT1 | cds-NP_015366.1_CAT1 | 72.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:624073-625290:+ | gene-YPR041W_CBS1585 | rna-NM_001184138.1_CBS1585 | cds-NP_015366.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:638437-639654:+ | gene-YPR041W_CBS436 | rna-NM_001184138.1_CBS436 | cds-NP_015366.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:627821-629038:+ | gene-YPR041W_CBS6412 | rna-NM_001184138.1_CBS6412 | cds-NP_015366.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:621022-622239:+ | gene-YPR041W_CBS6413 | rna-NM_001184138.1_CBS6413 | cds-NP_015366.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:648679-649896:+ | gene-YPR041W_CENPK1137D | rna-NM_001184138.1_CENPK1137D | cds-NP_015366.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:618310-619527:+ | gene-YPR041W_EthanolRed | rna-NM_001184138.1_EthanolRed | cds-NP_015366.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:626113-627330:+ | gene-YPR041W_FaliES1 | rna-NM_001184138.1_FaliES1 | cds-NP_015366.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:581-1798:- | gene-YPR041W_JAY291 | rna-NM_001184138.1_JAY291 | cds-NP_015366.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:639238-640455:+ | gene-YPR041W_MUCL30387 | rna-NM_001184138.1_MUCL30387 | cds-NP_015366.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:637933-639150:+ | gene-YPR041W_MUCL30388 | rna-NM_001184138.1_MUCL30388 | cds-NP_015366.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:617330-618547:+ | gene-YPR041W_MUCL39482 | rna-NM_001184138.1_MUCL39482 | cds-NP_015366.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:680129-681346:+ | gene-YPR041W_MUCL42920 | rna-NM_001184138.1_MUCL42920 | cds-NP_015366.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:648687-649904:+ | gene-YPR041W_NCIM3186 | rna-NM_001184138.1_NCIM3186 | cds-NP_015366.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:625262-626479:+ | gene-YPR041W_NCYC1407 | rna-NM_001184138.1_NCYC1407 | cds-NP_015366.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:631468-632685:+ | gene-YPR041W_PE2H3 | rna-NM_001184138.1_PE2H3 | cds-NP_015366.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:631116-632333:+ | gene-YPR041W_PE2H4 | rna-NM_001184138.1_PE2H4 | cds-NP_015366.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:648704-649921:+ | gene-YPR041W_S288C | rna-NM_001184138.1_S288C | cds-NP_015366.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:50849-52066:- | gene-YPR041W_SA1 | rna-NM_001184138.1_SA1 | cds-NP_015366.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:625913-627130:+ | gene-YPR041W_ThermosaccDry | rna-NM_001184138.1_ThermosaccDry | cds-NP_015366.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:642130-643347:+ | gene-YPR041W_VR1 | rna-NM_001184138.1_VR1 | cds-NP_015366.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:625228-626445:+ | gene-YPR041W_ZTW1 | rna-NM_001184138.1_ZTW1 | cds-NP_015366.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:626020-627234:+ | gene-YPR041W_Sparadoxus | rna-NM_001184138.1_Sparadoxus | cds-NP_015366.1_Sparadoxus | 93.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |